ID F1L6P8_ASCSU Unreviewed; 486 AA.
AC F1L6P8;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=long-chain-fatty-acid--CoA ligase {ECO:0000256|ARBA:ARBA00026121};
DE EC=6.2.1.3 {ECO:0000256|ARBA:ARBA00026121};
DE Flags: Fragment;
OS Ascaris suum (Pig roundworm) (Ascaris lumbricoides).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX NCBI_TaxID=6253 {ECO:0000313|EMBL:ADY45802.1};
RN [1] {ECO:0000313|EMBL:ADY45802.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=21685128; DOI=10.1101/gr.121426.111;
RA Wang J., Czech B., Crunk A., Wallace A., Mitreva M., Hannon G.J.,
RA Davis R.E.;
RT "Deep small RNA sequencing from the nematode Ascaris reveals conservation,
RT functional diversification, and novel developmental profiles.";
RL Genome Res. 21:1462-1477(2011).
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DR EMBL; JI172528; ADY45802.1; -; mRNA.
DR AlphaFoldDB; F1L6P8; -.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43272:SF89; ARACHIDONATE--COA LIGASE; 1.
DR PANTHER; PTHR43272; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 2: Evidence at transcript level;
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ADY45802.1};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022832}.
FT DOMAIN 33..300
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT NON_TER 486
FT /evidence="ECO:0000313|EMBL:ADY45802.1"
SQ SEQUENCE 486 AA; 54133 MW; 95BAF3929D5446C2 CRC64;
MKTSSDFRNG PHRKCTQVEM YDWDHIMRVG SANLKPVTPP SPSSIYMICH TSGTTGTPKG
VQLSHRALLA SMAGLYVQWC VPPHSMSFDN SDIHLSFLSL AHIYEQLLEL FMIYVGGRVG
VFGGDVRKLL DDMAVFRPTI VALVPRLLNR FHERILQEIA HQNPIKRLLF EIAVKSKLKT
LSKGEMCFDT VWDKLVFSKF HARFGGNLRL LTTGGAPVSK EVMRFSRIAY GCPVFEGYGQ
TECCAAGTIT LPFDVEGGHV GGPAAWAEIK LIDVDELQYC AENDIGEVCF RGAALMNGYF
NDPDLTSKAV DEQGWLHTGD IGEWLPNGSL RIIGRRNNVF KLAQGDFVSP EQVENIYLQH
PIVKQVFVYG SSQRAYLVAI VVVDVTLLRK QYATPSTQQE KTTQSSSTAS LLSDIGVRRK
FLLDLRKLGS CKGLTGIEQI NNLYLTADEF TAESGLLTPT LKIKRTALAD RFAENIEQLY
SRDLLI
//
