ID F1LIV0_PSEPU Unreviewed; 63 AA.
AC F1LIV0;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=2-hydroxymuconate tautomerase {ECO:0000256|ARBA:ARBA00015750, ECO:0000256|RuleBase:RU362032};
DE EC=5.3.2.6 {ECO:0000256|ARBA:ARBA00012667, ECO:0000256|RuleBase:RU362032};
DE AltName: Full=4-oxalocrotonate tautomerase {ECO:0000256|ARBA:ARBA00029674, ECO:0000256|RuleBase:RU362032};
GN Name=xylHI {ECO:0000313|EMBL:BAF02439.1};
GN ORFNames=BGP82_26970 {ECO:0000313|EMBL:POF99508.1};
OS Pseudomonas putida (Arthrobacter siderocapsulatus).
OG Plasmid pWW53 {ECO:0000313|EMBL:BAF02439.1}.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=303 {ECO:0000313|EMBL:BAF02439.1};
RN [1] {ECO:0000313|EMBL:BAF02439.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MT53 {ECO:0000313|EMBL:BAF02439.1};
RC PLASMID=pWW53 {ECO:0000313|EMBL:BAF02439.1};
RX PubMed=2997136;
RA Keil H., Keil S., Pickup R.W., Williams P.A.;
RT "Evolutionary conservation of genes coding for meta pathway enzymes within
RT TOL plasmids pWW0 and pWW53.";
RL J. Bacteriol. 164:887-895(1985).
RN [2] {ECO:0000313|EMBL:BAF02439.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MT53 {ECO:0000313|EMBL:BAF02439.1};
RC PLASMID=pWW53 {ECO:0000313|EMBL:BAF02439.1};
RX PubMed=3027047;
RA Keil H., Saint C.M., Williams P.A.;
RT "Gene organization of the first catabolic operon of TOL plasmid pWW53:
RT production of indigo by the xylA gene product.";
RL J. Bacteriol. 169:764-770(1987).
RN [3] {ECO:0000313|EMBL:BAF02439.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MT53 {ECO:0000313|EMBL:BAF02439.1};
RC PLASMID=pWW53 {ECO:0000313|EMBL:BAF02439.1};
RX PubMed=3309179;
RA Keil H., Keil S., Williams P.A.;
RT "Molecular analysis of regulatory and structural xyl genes of the TOL
RT plasmid pWW53-4.";
RL J. Gen. Microbiol. 133:1149-1158(1987).
RN [4] {ECO:0000313|EMBL:BAF02439.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MT53 {ECO:0000313|EMBL:BAF02439.1};
RC PLASMID=pWW53 {ECO:0000313|EMBL:BAF02439.1};
RX PubMed=3076178;
RA Osborne D.J., Pickup R.W., Williams P.A.;
RT "The presence of two complete homologous meta pathway operons on TOL
RT plasmid pWW53.";
RL J. Gen. Microbiol. 134:2965-2975(1988).
RN [5] {ECO:0000313|EMBL:BAF02439.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MT53 {ECO:0000313|EMBL:BAF02439.1};
RC PLASMID=pWW53 {ECO:0000313|EMBL:BAF02439.1};
RA Assinder S.J., De Marco P., Sayers J.R., Shaw L.E., Winson M.K.,
RA Williams P.A.;
RT "Identical resolvases are encoded by Pseudomonas TOL plasmids pWW53 and
RT pDK1.";
RL Nucleic Acids Res. 20:5476-5476(1992).
RN [6] {ECO:0000313|EMBL:BAF02439.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MT53 {ECO:0000313|EMBL:BAF02439.1};
RC PLASMID=pWW53 {ECO:0000313|EMBL:BAF02439.1};
RX PubMed=8473862; DOI=10.1099/00221287-139-3-557;
RA Assinder S.J., de Marco P., Osborne D.J., Poh C.L., Shaw L.E., Winson M.K.,
RA Williams P.A.;
RT "A comparison of the multiple alleles of xylS carried by TOL plasmids pWW53
RT and pDK1 and its implications for their evolutionary relationship.";
RL J. Gen. Microbiol. 139:557-568(1993).
RN [7] {ECO:0000313|EMBL:BAF02439.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MT53 {ECO:0000313|EMBL:BAF02439.1};
RC PLASMID=pWW53 {ECO:0000313|EMBL:BAF02439.1};
RX PubMed=9260942;
RA Gallegos M.T., Williams P.A., Ramos J.L.;
RT "Transcriptional control of the multiple catabolic pathways encoded on the
RT TOL plasmid pWW53 of Pseudomonas putida MT53.";
RL J. Bacteriol. 179:5024-5029(1997).
RN [8] {ECO:0000313|EMBL:BAF02439.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MT53 {ECO:0000313|EMBL:BAF02439.1};
RC PLASMID=pWW53 {ECO:0000313|EMBL:BAF02439.1};
RX PubMed=10877777; DOI=10.1128/AEM.66.7.2842-2852.2000;
RA Sentchilo V.S., Perebituk A.N., Zehnder A.J.B., van der Meer J.R.;
RT "Molecular diversity of plasmids bearing genes that encode toluene and
RT xylene metabolism in Pseudomonas strains isolated from different
RT contaminated sites in Belarus.";
RL Appl. Environ. Microbiol. 66:2842-2852(2000).
RN [9] {ECO:0000313|EMBL:BAF02439.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MT53 {ECO:0000313|EMBL:BAF02439.1};
RC PLASMID=pWW53 {ECO:0000313|EMBL:BAF02439.1};
RX PubMed=11591664; DOI=10.1128/JB.183.21.6215-6224.2001;
RA Tsuda M., Genka H.;
RT "Identification and characterization of Tn4656, a novel class II transposon
RT carrying a set of toluene-degrading genes from TOL plasmid pWW53.";
RL J. Bacteriol. 183:6215-6224(2001).
RN [10] {ECO:0000313|EMBL:BAF02439.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MT53 {ECO:0000313|EMBL:BAF02439.1};
RC PLASMID=pWW53 {ECO:0000313|EMBL:BAF02439.1};
RX PubMed=17408691; DOI=10.1016/j.jmb.2007.02.098;
RA Yano H., Garruto C.E., Sota M., Ohtsubo Y., Nagata Y., Zylstra G.J.,
RA Williams P.A., Tsuda M.;
RT "Complete sequence determination combined with analysis of
RT transposition/site-specific recombination events to explain genetic
RT organization of IncP-7 TOL plasmid pWW53 and related mobile genetic
RT elements.";
RL J. Mol. Biol. 369:11-26(2007).
RN [11] {ECO:0000313|EMBL:BAF02439.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MT53 {ECO:0000313|EMBL:BAF02439.1};
RC PLASMID=pWW53 {ECO:0000313|EMBL:BAF02439.1};
RX PubMed=22925377; DOI=10.1111/j.1462-2920.2012.02861.x;
RA Miyakoshi M., Shintani M., Inoue K., Terabayashi T., Sai F., Ohkuma M.,
RA Nojiri H., Nagata Y., Tsuda M.;
RT "ParI, an orphan ParA family protein from Pseudomonas putida KT2440-
RT specific genomic island, interferes with the partition system of IncP-7
RT plasmids.";
RL Environ. Microbiol. 14:2946-2959(2012).
RN [12] {ECO:0000313|EMBL:POF99508.1, ECO:0000313|Proteomes:UP000237378}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KH-18-2 {ECO:0000313|EMBL:POF99508.1,
RC ECO:0000313|Proteomes:UP000237378};
RA Seilhamer J.J.;
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
RN [13] {ECO:0000313|EMBL:POF99508.1, ECO:0000313|Proteomes:UP000237378}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KH-18-2 {ECO:0000313|EMBL:POF99508.1,
RC ECO:0000313|Proteomes:UP000237378};
RA Yoshizawa S., Khan N.H., Nishimura M., Chiura H.X., Ogura Y., Hayashi T.,
RA Kogure K.;
RT "Draft genome of Pseudomonas putida strain KH-18-2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the ketonization of 2-hydroxymuconate
CC stereoselectively to yield 2-oxo-3-hexenedioate.
CC {ECO:0000256|ARBA:ARBA00003024}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(2Z,4E)-2-hydroxyhexa-2,4-dienedioate = (3E)-2-oxohex-3-
CC enedioate; Xref=Rhea:RHEA:33431, ChEBI:CHEBI:28080,
CC ChEBI:CHEBI:64908; EC=5.3.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00001379,
CC ECO:0000256|RuleBase:RU362032};
CC -!- SUBUNIT: Homohexamer. {ECO:0000256|ARBA:ARBA00011643,
CC ECO:0000256|RuleBase:RU362032}.
CC -!- SIMILARITY: Belongs to the 4-oxalocrotonate tautomerase family.
CC {ECO:0000256|ARBA:ARBA00006723, ECO:0000256|RuleBase:RU362032}.
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DR EMBL; AB238971; BAF02439.1; -; Genomic_DNA.
DR EMBL; MING01000087; POF99508.1; -; Genomic_DNA.
DR RefSeq; WP_004575912.1; NZ_MING01000087.1.
DR RefSeq; YP_709329.1; NC_008275.1.
DR AlphaFoldDB; F1LIV0; -.
DR Proteomes; UP000237378; Unassembled WGS sequence.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR CDD; cd00491; 4Oxalocrotonate_Tautomerase; 1.
DR Gene3D; 3.30.429.10; Macrophage Migration Inhibitory Factor; 1.
DR InterPro; IPR018191; 4-OT.
DR InterPro; IPR004370; 4-OT-like_dom.
DR InterPro; IPR014347; Tautomerase/MIF_sf.
DR NCBIfam; TIGR00013; taut; 1.
DR PANTHER; PTHR35530:SF1; TAUTOMERASE BSL7456-RELATED; 1.
DR PANTHER; PTHR35530; TAUTOMERASE-RELATED; 1.
DR Pfam; PF01361; Tautomerase; 1.
DR SUPFAM; SSF55331; Tautomerase/MIF; 1.
PE 3: Inferred from homology;
KW Aromatic hydrocarbons catabolism {ECO:0000256|ARBA:ARBA00022797,
KW ECO:0000256|RuleBase:RU362032}; Isomerase {ECO:0000256|RuleBase:RU362032};
KW Plasmid {ECO:0000313|EMBL:BAF02439.1}.
FT DOMAIN 2..58
FT /note="4-oxalocrotonate tautomerase-like"
FT /evidence="ECO:0000259|Pfam:PF01361"
FT ACT_SITE 2
FT /note="Proton acceptor; via imino nitrogen"
FT /evidence="ECO:0000256|PIRSR:PIRSR618191-1"
SQ SEQUENCE 63 AA; 6968 MW; 3FEC3AB94A126802 CRC64;
MPIAQIHILE GRSDEQKETL IREVSEAISR SLDAPLTSVR VIITEMPKGH FGIGGELASK
VRR
//
