ID   F1LK77_9ROSI            Unreviewed;       406 AA.
AC   F1LK77;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Xanthine dehydrogenase {ECO:0000313|EMBL:ABX45981.1};
DE   Flags: Fragment;
GN   Name=Xdh {ECO:0000313|EMBL:ABX45981.1};
OS   Pilocarpus pennatifolius.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Sapindales; Rutaceae; Amyridoideae; Pilocarpus.
OX   NCBI_TaxID=77017 {ECO:0000313|EMBL:ABX45981.1};
RN   [1] {ECO:0000313|EMBL:ABX45981.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Morton C.M.;
RT   "Newly Sequenced Nuclear Gene (Xdh) for Inferring Angiosperm Phylogeny.";
RL   Ann. Mo. Bot. Gard. 98:63-89(2011).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR   EMBL; EU264408; ABX45981.1; -; Genomic_DNA.
DR   AlphaFoldDB; F1LK77; -.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.30.465.10; -; 1.
DR   Gene3D; 1.10.150.120; [2Fe-2S]-binding domain; 1.
DR   Gene3D; 3.30.390.50; CO dehydrogenase flavoprotein, C-terminal domain; 1.
DR   Gene3D; 3.30.43.10; Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2; 1.
DR   InterPro; IPR002888; 2Fe-2S-bd.
DR   InterPro; IPR036884; 2Fe-2S-bd_dom_sf.
DR   InterPro; IPR016208; Ald_Oxase/xanthine_DH-like.
DR   InterPro; IPR005107; CO_DH_flav_C.
DR   InterPro; IPR036683; CO_DH_flav_C_dom_sf.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016167; FAD-bd_PCMH_sub1.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR002346; Mopterin_DH_FAD-bd.
DR   PANTHER; PTHR45444:SF3; ALDEHYDE OXIDASE_XANTHINE DEHYDROGENASE, MOLYBDOPTERIN BINDING PROTEIN; 1.
DR   PANTHER; PTHR45444; XANTHINE DEHYDROGENASE; 1.
DR   Pfam; PF03450; CO_deh_flav_C; 1.
DR   Pfam; PF00941; FAD_binding_5; 1.
DR   Pfam; PF01799; Fer2_2; 1.
DR   SUPFAM; SSF55447; CO dehydrogenase flavoprotein C-terminal domain-like; 1.
DR   SUPFAM; SSF47741; CO dehydrogenase ISP C-domain like; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   4: Predicted;
FT   DOMAIN          132..317
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51387"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ABX45981.1"
FT   NON_TER         406
FT                   /evidence="ECO:0000313|EMBL:ABX45981.1"
SQ   SEQUENCE   406 AA;  45321 MW;  9539B05C68EED939 CRC64;
     VMSMYVLLRS SQTPPTEELI EESLAGNLCR CTGYRPIVDA FRVFAKTNDA LYTNLYSMSL
     KEGEFVCPST GKPCSCGIKN VSNADTCGKT VTCGKIYEPV SYSEIDGSTY TEKELIFPPE
     LLLRKSTPLS LYGFGGLKWY RPIKLQHVLE LKSKYPDAKL LVGNTEVGIE MRLKRMQYQV
     LISVTHVPEL NMLNVKDDGL EIGAAVRLTE LLRTFRKVVT ERPAHETSSC KAFIEQIKWF
     AGTQIKNVAS VGGNICTASP ISDLNPLWMA SRAKFRIIDC EGNIRMAMAE EFFLGYRKVD
     LASGEILLSV FLPWTRPFEF VKEFKQAHRR DDDIALVNAG MRIFLEEKGE ELVVSGASIV
     YGGVAPLSLS AVKTKAFIIG KSWTQELLQN ALKILQTDII LKEDAP
//