ID F1MFI5_BOVIN Unreviewed; 2080 AA.
AC F1MFI5;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 3.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Sidekick cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSBTAP00000005275.6};
GN Name=SDK1 {ECO:0000313|Ensembl:ENSBTAP00000005275.6,
GN ECO:0000313|VGNC:VGNC:34393};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000005275.6, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000005275.6, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000005275.6,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000005275.6}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000005275.6};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR SMR; F1MFI5; -.
DR STRING; 9913.ENSBTAP00000005275; -.
DR Ensembl; ENSBTAT00000005275.6; ENSBTAP00000005275.6; ENSBTAG00000004035.7.
DR VEuPathDB; HostDB:ENSBTAG00000004035; -.
DR VGNC; VGNC:34393; SDK1.
DR eggNOG; KOG3510; Eukaryota.
DR eggNOG; KOG4221; Eukaryota.
DR GeneTree; ENSGT00940000157747; -.
DR HOGENOM; CLU_001875_1_0_1; -.
DR InParanoid; F1MFI5; -.
DR OMA; FMDADQR; -.
DR TreeFam; TF316846; -.
DR Reactome; R-BTA-373756; SDK interactions.
DR Proteomes; UP000009136; Chromosome 25.
DR Bgee; ENSBTAG00000004035; Expressed in fornix of vagina and 98 other cell types or tissues.
DR ExpressionAtlas; F1MFI5; baseline.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0048148; P:behavioral response to cocaine; IEA:Ensembl.
DR GO; GO:0060998; P:regulation of dendritic spine development; IEA:Ensembl.
DR CDD; cd00063; FN3; 12.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 19.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR PANTHER; PTHR44170:SF46; PROTEIN SIDEKICK-1 ISOFORM X1; 1.
DR Pfam; PF00041; fn3; 12.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 3.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 13.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 6.
DR SUPFAM; SSF49265; Fibronectin type III; 7.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 12.
DR PROSITE; PS50835; IG_LIKE; 6.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..2080
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018633524"
FT TRANSMEM 1885..1908
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..105
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 121..199
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 212..300
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 305..395
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 399..488
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 493..582
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 589..685
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 690..786
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 791..889
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 893..987
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 991..1090
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1095..1193
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1198..1295
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1299..1393
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1398..1495
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1500..1618
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1623..1719
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1720..1820
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1952..1974
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2015..2059
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2080 AA; 227112 MW; 82D48A107145D7CE CRC64;
MCFPLSFFSS LSFFFNVSDD VVPYFKTEPG LPQIHLEGNR LVLTCLAEGS WPLEFKWTHN
DSELTTYTSE YKYVIPSLQR LDAGFYRCIV RNRMGALLQR RSEVQVAYMG DFTDADERRV
VSEGRAAVLS LPPISSCPRP QVTWFRDGHK IIPSSRIAIT LENQLVILAA AASDAGAYYV
QAVNERNGEN KTSPPVHLSI ARDTGMPEAV APVIVVPPSN RSVVAGSSET TLECIANARP
AEELSVTWKR NGVRVTTGLH GFGRRLTISN PTSSDTGVYI CEAALPGSAF EPARARAFLS
IIEPPYFIAE PKSRILAEVE ENVDIVCEAM GVPPPALQWF KDAISINKLQ NPRYQVLAGG
GLRVRQLRPE DSGIFQCLAS NAGGEVQTHT YLDVTNVAPA FTQLPVDTTV TDGTTAVLRC
EVSGAPRPAI VWSRGSHILA SGSVRIPRFM LLESGGLQIA PVSIQDAGSY TCHAANSEGS
LDASATLTVW NRTSIVTPPE DLVVIKGTTA TLHCGATHDP RISLRYVWKK DNVVIAPSSS
SRVVVEKDGS LLISQTWSGD IGDYTCGVIS EGGNDSRTAR LEVIELPHSP QNLVASLNPA
HSHAVVLSWV RPFDGNSPVL YYIVELSENN SPWKVHLSDV GPEMTGVTVR GLTPARTYQF
RVCAVNQVGK GQYSAETSRL MLPEEPPSAP PKNIVASGRT NQSIMVQWQP PPEPEHNGVL
RGYILRYRLA GLPGEYQQRN ISSPEVSYCL VTELIIWTQY EIQVAAYNGA GLGVFSRAVT
EYTLQGVPTA PPQNVQVEAV NSTTIQFLWN PPPQQFINGI NQGYKLLAWP DDVPEAVTVV
TIAPDFHGVH HGYITNLKKF TAYFTSVLCF TTPGDGPPST PQLIRTHEDK PGAVGHLSFT
EILDTSLKVS WQEPLEKNGI ITGYQVSWEV YGQSTSRLTL TLNSSTHEYK IQGLSSLTTY
TIDVAAVTAA GAGVPTSSTI SSGVPPELPG APSNLVISNI SPRSATLQFR PGYDGKTAIS
RWIVQGQVGA IGDEEEWVTL CEEENEPDAQ MLEIPDLTPY THYRFRMRQA NVVGAGPFSQ
SSRVIQTLQA PPDVAPTSIT VRTASETSLR LRWVPLPDSQ YNGNPESVGY RIKYWCPDLP
SAVLTQVISD RLEREFTVEG LEEWTEYELQ MQAFNAIGAG PWSAAVRGRT RESVPSAAPE
NVSAEAVSST QILLTWASVP EPDQNGLILG YKILFRAKDL DPEPRSHVVR GNHTQSALLA
GLGKFVLYEL QVLAFTRIGN GVPSVPPILE RTKDDAPGPP VRLVFPEVRL TSVRIVWQPP
EEPNGIILGY QIAYRLASSS PNTFTTVEVG ATVRQFTATE LAPESAYVFR LSAKTRQGWG
EPLEATVITT EKRERPAPPR ELQVPQADVT ARSLCLRWVP GSDGASPIRY FTLQLRELPR
GQWQTYSSSI SHEATACVVE RLRPFTSYKL RLKATNDIGD SDFSAETEAV TTLQDVPGEP
PRSVSVTPRT TSSVLIQWQP PRDESLNGLL QGYRIYYREL EYEAAPATES KTLKTPSALR
AELTAQSSFK TVNSSSTETT YELTHLKKYR RYEVVLTAYN VIGEGPASAP VEVFVGEAAP
AQAPQRVHVN PLTASQLEVA WEPPPPESQN GIIQGYKIYY WEADSQNDTE KMRVLFLPET
TAKLKNLTSH TKYLVSISAF NAAGDGPRSE PQPGCTHQAA PGTPSFLAFS EITSTTLNVS
WGEPVAANGV LQGYRVVYEP LAPVQGVSKV VTVDVKGNWP RWLKVRDLTK GVTYFFRVQA
RTIAYGPELQ ANVTAGPAED EGLWDMFAKD IPRGATAYTV SLDQLRQGVT YEFRVVAVNQ
AGYGEPSSPS AAVSAQVETP FYEQWWFLLV MALSSLLVIL LVVFSLLLHG QSKKYRNCGT
GKSISNTEES VTLDNGGFAA LELNSRHLNV KNTFSKKNGT RSPPRPSPGG LHYSDEDLCN
KYNGAALTES GALQEKPGDA TESEVGARAL LRAAAPPVAP GPCPGLSRVS THTQARSRQS
RDRGRPFPDG EGPCSSLVRE ATSPISPWSR VDFGFANLLA
//
