GenomeNet

Database: UniProt
Entry: F1NDA1_CHICK
LinkDB: F1NDA1_CHICK
Original site: F1NDA1_CHICK 
ID   F1NDA1_CHICK            Unreviewed;       599 AA.
AC   F1NDA1;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 2.
DT   22-NOV-2017, entry version 43.
DE   SubName: Full=Eukaryotic translation initiation factor 2D {ECO:0000313|Ensembl:ENSGALP00000001253};
GN   Name=EIF2D {ECO:0000313|Ensembl:ENSGALP00000001253};
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
OC   Phasianidae; Phasianinae; Gallus.
OX   NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00000001253, ECO:0000313|Proteomes:UP000000539};
RN   [1] {ECO:0000313|Ensembl:ENSGALP00000001253, ECO:0000313|Proteomes:UP000000539}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000001253,
RC   ECO:0000313|Proteomes:UP000000539};
RX   PubMed=15592404; DOI=10.1038/nature03154;
RG   International Chicken Genome Sequencing Consortium;
RA   Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C.,
RA   Ponting C.P., Bork P., Burt D.W., Groenen M.A.M., Delany M.E.,
RA   Dodgson J.B., Chinwalla A.T., Cliften P.F., Clifton S.W.,
RA   Delehaunty K.D., Fronick C., Fulton R.S., Graves T.A., Kremitzki C.,
RA   Layman D., Magrini V., McPherson J.D., Miner T.L., Minx P., Nash W.E.,
RA   Nhan M.N., Nelson J.O., Oddy L.G., Pohl C.S., Randall-Maher J.,
RA   Smith S.M., Wallis J.W., Yang S.-P., Romanov M.N., Rondelli C.M.,
RA   Paton B., Smith J., Morrice D., Daniels L., Tempest H.G.,
RA   Robertson L., Masabanda J.S., Griffin D.K., Vignal A., Fillon V.,
RA   Jacobbson L., Kerje S., Andersson L., Crooijmans R.P., Aerts J.,
RA   van der Poel J.J., Ellegren H., Caldwell R.B., Hubbard S.J.,
RA   Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M., Arakawa H.,
RA   Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K.,
RA   Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E.,
RA   Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M.,
RA   Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S.,
RA   Miller M.M., Inoko H., Shiina T., Kaufman J., Salomonsen J.,
RA   Skjoedt K., Wong G.K.-S., Wang J., Liu B., Wang J., Yu J., Yang H.,
RA   Nefedov M., Koriabine M., Dejong P.J., Goodstadt L., Webber C.,
RA   Dickens N.J., Letunic I., Suyama M., Torrents D., von Mering C.,
RA   Zdobnov E.M., Makova K., Nekrutenko A., Elnitski L., Eswara P.,
RA   King D.C., Yang S.-P., Tyekucheva S., Radakrishnan A., Harris R.S.,
RA   Chiaromonte F., Taylor J., He J., Rijnkels M., Griffiths-Jones S.,
RA   Ureta-Vidal A., Hoffman M.M., Severin J., Searle S.M.J., Law A.S.,
RA   Speed D., Waddington D., Cheng Z., Tuzun E., Eichler E., Bao Z.,
RA   Flicek P., Shteynberg D.D., Brent M.R., Bye J.M., Huckle E.J.,
RA   Chatterji S., Dewey C., Pachter L., Kouranov A., Mourelatos Z.,
RA   Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M.,
RA   Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O.,
RA   Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J.,
RA   Betran E., Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G.,
RA   Furey T.S., Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D.,
RA   Eyras E., Castelo R., Abril J.F., Castellano S., Camara F., Parra G.,
RA   Guigo R., Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A.,
RA   Mardis E.R., Wilson R.K.;
RT   "Sequence and comparative analysis of the chicken genome provide
RT   unique perspectives on vertebrate evolution.";
RL   Nature 432:695-716(2004).
RN   [2] {ECO:0000313|Ensembl:ENSGALP00000001253}
RP   IDENTIFICATION.
RC   STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000001253};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSGALP00000001253}.
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DR   EMBL; AADN04000216; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001006322.2; NM_001006322.2.
DR   UniGene; Gga.7117; -.
DR   STRING; 9031.ENSGALP00000001253; -.
DR   PaxDb; F1NDA1; -.
DR   Ensembl; ENSGALT00000001255; ENSGALP00000001253; ENSGALG00000000856.
DR   GeneID; 419845; -.
DR   CTD; 1939; -.
DR   eggNOG; KOG2522; Eukaryota.
DR   eggNOG; ENOG410XSAV; LUCA.
DR   GeneTree; ENSGT00550000074865; -.
DR   InParanoid; F1NDA1; -.
DR   OMA; REQPYHP; -.
DR   OrthoDB; EOG091G0DTH; -.
DR   TreeFam; TF105830; -.
DR   Proteomes; UP000000539; Chromosome 26.
DR   Bgee; ENSGALG00000000856; -.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IEA:Ensembl.
DR   GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR   GO; GO:0003743; F:translation initiation factor activity; IBA:GO_Central.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IBA:GO_Central.
DR   GO; GO:0002192; P:IRES-dependent translational initiation of linear mRNA; IBA:GO_Central.
DR   GO; GO:0075522; P:IRES-dependent viral translational initiation; IEA:Ensembl.
DR   GO; GO:0032790; P:ribosome disassembly; IEA:Ensembl.
DR   Gene3D; 1.10.245.10; -; 1.
DR   Gene3D; 2.30.130.10; -; 1.
DR   Gene3D; 3.30.780.10; -; 1.
DR   InterPro; IPR002478; PUA.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR036974; PUA_sf.
DR   InterPro; IPR001950; SUI1.
DR   InterPro; IPR036877; SUI1_dom_sf.
DR   InterPro; IPR036885; SWIB_MDM2_dom_sf.
DR   Pfam; PF01253; SUI1; 1.
DR   SUPFAM; SSF47592; SSF47592; 1.
DR   SUPFAM; SSF55159; SSF55159; 1.
DR   SUPFAM; SSF88697; SSF88697; 1.
DR   PROSITE; PS50890; PUA; 1.
DR   PROSITE; PS50296; SUI1; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000539};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000539}.
FT   DOMAIN       93    173       PUA. {ECO:0000259|PROSITE:PS50890}.
FT   DOMAIN      506    579       SUI1. {ECO:0000259|PROSITE:PS50296}.
SQ   SEQUENCE   599 AA;  66429 MW;  738114A77D483B92 CRC64;
     MFCKAFRVKA STAIKGSDRR KLRADVAAAF PGLSAEQLVE LIPNKEELNV IRIYTHKGEA
     VTVYADSRNP ILFEIEKALY PTVYTLWVYP DLLPAFSTWP PVLQKLAGGA DLMLPGVVVP
     SSGFPQVERG TLCAVTLLGN RAPVAVAAAA MSTAEMLAAG MKGKGFAVLH TYMDHLWEYG
     DKSSPPTLAP LAADPAEKEN AEDEEEVEGK KPGNSFSTDT PQHVDIGDLS LKEQNSCAIV
     MGKEELNENR AAETAEDDST GAQQDAEDSR TPQEQMDVLF NQCFFHALKC KVKKSDLPLL
     TSTFLRSHMF SCCPAGQQLD IKKSSYKKFS KFLQSMQHQK ILQVKELTKG VESIVEVDWK
     HPDIKAFAVP EGFSSASAAQ DSKSEDREQA YRAPEIIPMY GVSAKMVPLF QDSGHRKGSI
     LSSSEVRNII INYVKTNELV DETNKNFVKV NAILCDCLLD KSEQDEVSHL KWDDLVSRCL
     ERLQPLHQVT FFGQEPIVRK GNIEPIDITT AQRSSNKKVT IIKNLELYGL DPQCVANILQ
     QKVQASTTIT PVPGAKDRVQ VQIQGNQVHH LAKMLLEEYQ LPRKYIQGLE KAPKLGRKK
//
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