ID F1NG39_CHICK Unreviewed; 1028 AA.
AC F1NG39;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Myosin IC {ECO:0000313|Ensembl:ENSGALP00010043641.1};
GN Name=MYO1C {ECO:0000313|Ensembl:ENSGALP00010043641.1};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010043641.1, ECO:0000313|Proteomes:UP000000539};
RN [1] {ECO:0000313|Ensembl:ENSGALP00010043641.1}
RP IDENTIFICATION.
RC STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010043641.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, stereocilium membrane
CC {ECO:0000256|ARBA:ARBA00004289}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}. Membrane
CC {ECO:0000256|ARBA:ARBA00004370}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR RefSeq; XP_015151229.1; XM_015295743.1.
DR RefSeq; XP_015151230.1; XM_015295744.1.
DR AlphaFoldDB; F1NG39; -.
DR Ensembl; ENSGALT00010070950.1; ENSGALP00010043641.1; ENSGALG00010029337.1.
DR GeneID; 417555; -.
DR CTD; 4641; -.
DR VEuPathDB; HostDB:geneid_417555; -.
DR GeneTree; ENSGT00940000157915; -.
DR Proteomes; UP000000539; Chromosome 19.
DR Bgee; ENSGALG00000002709; Expressed in colon and 14 other cell types or tissues.
DR ExpressionAtlas; F1NG39; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0060171; C:stereocilium membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01378; MYSc_Myo1; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR010926; Myosin_TH1.
DR InterPro; IPR036072; MYSc_Myo1.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF255; UNCONVENTIONAL MYOSIN-IC; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF06017; Myosin_TH1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 2.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 2.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51757; TH1; 1.
PE 1: Evidence at protein level;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Proteomics identification {ECO:0007829|PeptideAtlas:F1NG39};
KW Reference proteome {ECO:0000313|Proteomes:UP000000539}.
FT REGION 573..595
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT BINDING 105..112
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1028 AA; 118877 MW; 060FE2F8F4575C85 CRC64;
MESALTARDR VGVQDFVLLE NFTSEAAFIE NLRKRFKENL IYTYIGSVLV SVNPYKELEI
YSKQNMERYR GVSFYEVSPH LYAIADNSYR SLRTERKDQC ILISGESGAG KTEATKKILQ
YYAVTCPASQ QVETVKDRLL QSNPVLEAFG NAKTLRNDNS SRFGKYMDVQ FDYRGAPVGG
HILNYLLEKS RVVHQNHGER NFHIFYQLLE GGEEDLLRRL GLEKNPQQYH YLVKGHCARV
SSINDKNDWK VVRRALSIIS FNDNEVEDLL SIVASVLHLG NVQFAADEQG NAQVTTENQI
KYLARLLAVE GSVLRDALIH KKIIAKGEEL ISPLNLEQAA YARDALAKAI YGRTFSWLVN
KVNKSLAYKE GEFPGWRSTT VLGLLDIYGF EVFQHNSFEQ FCINYCNEKL QQLFIELTLK
SEQEEYESEG IAWEPVQYFN NKIICDLVEE KFKGIISILD EECLRPGDAT DTTFLEKLEE
TVKNHPHFLT HKLADQKTRK SLGREEFRLL HYAGEVTYSV AGFLDKNNDL LFRNLKETMC
NSENPIINQC FDRTELTDKK RPETAATQFK NSLSKLMEIL MSKEPSYIRC IKPNDAKQAD
RFDEVLIRHQ VKYLGLMENL RVRRAGFAYR RKYEVFLQRY KSLCPETWPT WDGRPHDGVA
VLVKHLGYKQ EEYKMGRTKI FIRFPKTLFA TEDALEVRKQ SLATKMQATW RGFYRRKKFL
HMKHSAIAIQ SWWRGTLGRR KAAKRKWAVQ TIRRFIKGFI YRNHPRCPEN EYFLDYIRFS
FLMNLKRNLP KNVLDKSWPT PPPSLCEASQ LLRQLCMQNM VWTYCKRISP EWKQQLEQKV
IASEIFKGKK DNYPQSVPRL FINTRLGNEE INAKVLQALE NEAIKYAVPV IKYDRKGYKA
RSRQLLLTQN AVIIVEDSKI KQRIDYANLT GISVSSLSDN LFVLHVHCED NKQKGDVVLQ
SDHVIETLTK TAMRADKVNN ININQGSIKF TVGQGKEGII DFISGSELLI AKAKNGHLTV
VAPRLNSR
//
