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Database: UniProt
Entry: F1P435_CHICK
LinkDB: F1P435_CHICK
Original site: F1P435_CHICK 
ID   F1P435_CHICK            Unreviewed;      1770 AA.
AC   F1P435;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 3.
DT   25-OCT-2017, entry version 53.
DE   SubName: Full=Calcium voltage-gated channel subunit alpha1 H {ECO:0000313|Ensembl:ENSGALP00000008367};
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
OC   Phasianidae; Phasianinae; Gallus.
OX   NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00000008367, ECO:0000313|Proteomes:UP000000539};
RN   [1] {ECO:0000313|Ensembl:ENSGALP00000008367, ECO:0000313|Proteomes:UP000000539}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000008367,
RC   ECO:0000313|Proteomes:UP000000539};
RX   PubMed=15592404; DOI=10.1038/nature03154;
RG   International Chicken Genome Sequencing Consortium;
RA   Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C.,
RA   Ponting C.P., Bork P., Burt D.W., Groenen M.A.M., Delany M.E.,
RA   Dodgson J.B., Chinwalla A.T., Cliften P.F., Clifton S.W.,
RA   Delehaunty K.D., Fronick C., Fulton R.S., Graves T.A., Kremitzki C.,
RA   Layman D., Magrini V., McPherson J.D., Miner T.L., Minx P., Nash W.E.,
RA   Nhan M.N., Nelson J.O., Oddy L.G., Pohl C.S., Randall-Maher J.,
RA   Smith S.M., Wallis J.W., Yang S.-P., Romanov M.N., Rondelli C.M.,
RA   Paton B., Smith J., Morrice D., Daniels L., Tempest H.G.,
RA   Robertson L., Masabanda J.S., Griffin D.K., Vignal A., Fillon V.,
RA   Jacobbson L., Kerje S., Andersson L., Crooijmans R.P., Aerts J.,
RA   van der Poel J.J., Ellegren H., Caldwell R.B., Hubbard S.J.,
RA   Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M., Arakawa H.,
RA   Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K.,
RA   Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E.,
RA   Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M.,
RA   Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S.,
RA   Miller M.M., Inoko H., Shiina T., Kaufman J., Salomonsen J.,
RA   Skjoedt K., Wong G.K.-S., Wang J., Liu B., Wang J., Yu J., Yang H.,
RA   Nefedov M., Koriabine M., Dejong P.J., Goodstadt L., Webber C.,
RA   Dickens N.J., Letunic I., Suyama M., Torrents D., von Mering C.,
RA   Zdobnov E.M., Makova K., Nekrutenko A., Elnitski L., Eswara P.,
RA   King D.C., Yang S.-P., Tyekucheva S., Radakrishnan A., Harris R.S.,
RA   Chiaromonte F., Taylor J., He J., Rijnkels M., Griffiths-Jones S.,
RA   Ureta-Vidal A., Hoffman M.M., Severin J., Searle S.M.J., Law A.S.,
RA   Speed D., Waddington D., Cheng Z., Tuzun E., Eichler E., Bao Z.,
RA   Flicek P., Shteynberg D.D., Brent M.R., Bye J.M., Huckle E.J.,
RA   Chatterji S., Dewey C., Pachter L., Kouranov A., Mourelatos Z.,
RA   Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M.,
RA   Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O.,
RA   Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J.,
RA   Betran E., Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G.,
RA   Furey T.S., Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D.,
RA   Eyras E., Castelo R., Abril J.F., Castellano S., Camara F., Parra G.,
RA   Guigo R., Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A.,
RA   Mardis E.R., Wilson R.K.;
RT   "Sequence and comparative analysis of the chicken genome provide
RT   unique perspectives on vertebrate evolution.";
RL   Nature 432:695-716(2004).
RN   [2] {ECO:0000313|Ensembl:ENSGALP00000008367}
RP   IDENTIFICATION.
RC   STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000008367};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSGALP00000008367}.
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DR   EMBL; AADN04000130; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9031.ENSGALP00000008367; -.
DR   Ensembl; ENSGALT00000008381; ENSGALP00000008367; ENSGALG00000005215.
DR   GeneTree; ENSGT00830000128242; -.
DR   InParanoid; F1P435; -.
DR   OrthoDB; EOG091G02L1; -.
DR   TreeFam; TF313555; -.
DR   Proteomes; UP000000539; Chromosome 14.
DR   Bgee; ENSGALG00000005215; -.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR   GO; GO:0008332; F:low voltage-gated calcium channel activity; IEA:Ensembl.
DR   GO; GO:0097110; F:scaffold protein binding; IEA:Ensembl.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IBA:GO_Central.
DR   GO; GO:0032342; P:aldosterone biosynthetic process; IEA:Ensembl.
DR   GO; GO:0070509; P:calcium ion import; IEA:Ensembl.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0035865; P:cellular response to potassium ion; IEA:Ensembl.
DR   GO; GO:0034651; P:cortisol biosynthetic process; IEA:Ensembl.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:GO_Central.
DR   GO; GO:0019228; P:neuronal action potential; IBA:GO_Central.
DR   GO; GO:2000344; P:positive regulation of acrosome reaction; IEA:Ensembl.
DR   GO; GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IBA:GO_Central.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR005445; VDCC_T_a1.
DR   Pfam; PF00520; Ion_trans; 3.
DR   PRINTS; PR01629; TVDCCALPHA1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000539};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000539};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    136    157       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    169    192       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    257    279       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    333    357       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    693    713       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    733    758       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    793    812       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    892    915       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    971    988       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1008   1027       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1106   1126       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1138   1158       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1193   1214       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      135    362       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      653    925       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      971   1224       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED      924    951       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1770 AA;  198527 MW;  63FDB92FE1CB55C6 CRC64;
     MAAMLQGGHG HEELTVHSPI AGLRRTPSRL SGLSVACPLP SPPGGTLSCE LQDCPFCASL
     LEDPEFAFSE SDSCDSDSNG IYEFTQDLRH GDHRDQLQQQ RGRRKRKKKK PKERNKVTRL
     WKAFGSKLKR IVESKYFNRG IMIAILINTL SMGIEYHEQP DELTNALEIS NIVFTSMFAL
     EMLLKLLAFG LFGYIKNPYN IFDGIIVVIS VWEIIGQSDG GLSVLRTFRL LRVLKLVRFM
     PALRRQLVVL MKTMDNVATF CMLLMLFIFI FSILGMHLFG CKFSLKTDTG DTVPDRKNFD
     SLLWAIVTVF QILTQEDWNV VLYNGMASTS SWAALYFVAL MTFGNYVLFN LLVAILVEGF
     QAEGDANRSD TDEDKTSANF DDDFEKLKDL RATEMKMYSL AVTPNGHLEG RGSMPPPIIM
     RTAATPMPTP KCSPHMDSVH TFVDSRRGSN ASLDPLTYDQ KSSSSLRSSP CANWGTNSNW
     GSRRSSWNSL GRAPSLKKKN QSGERESLLS GEGKGSTDDD SDDAKSSTVS RPSLHRRAES
     LDYRSSLDLP ELLQLPPMRH SLSISPMAVL PAEYQDCNGK MVHVPSEFFL HIDGHKEEAV
     DYEDDMEDSY CYRIRKVLEP YKPEWCKSHE DWSLYLFSPQ NRFRVMCQKV IAHKMFDHVV
     LVFIFLNCIT IALERPDIDP HSTERIFLSV SNYIFTAIFV AEMMVKVVAL GFFSGENTYL
     QSSWNVLDGV LVFVSIIDII VSMASAGGAK ILGVLRVLRL LRTLRPLRVI SRAPGLKLVV
     ETLISSLRPI GNIVLICCAF FIIFGILGVQ LFKGKFYYCD GPDVKNITTK TDCTNAHYRW
     VRRKYNFDNL GQALMSLFVL SSKDGWVNIM YDGLDAVGID QQPIQNHNPW MLLYFISFLL
     IVSFFVLNMF VGVVVENFHK CRQHQEAEEA RRREEKRLRR LEKKRRKAQR RPYYADYSPA
     RKYIHTLCTS HYLDLFITFI IGVNVITMSM EHYNQPKSLD EALKYCNYVF TIVFVFEAVL
     KLVAFGFRRF FKDRWNQLDL AIVLLSIVGI TLEEIEMNAA LPINPTIIRI MRVLRIARVL
     KLLKMATGMR ALLDTVVQAL PQVGNLGLLF MLLFFIYAAL GVELFGKLDC SEENPCEGLS
     RHATFTNFGM AFLTLFRVST GDNWNGIMKD TLRECTREDK HCLSYLPVIS PVYFVTFVLI
     AQFVLVNVVV AVLMKHLEES NKEAKEDAEM DAEIELEMSR GASTTSGSRG GAVALESRAS
     CRSQEAMKSE PAAQAKHQAL GGTAIPQPQD SQNMLTVRKI SVSRMHSLPN DSYMFRPVMP
     AKAPFPLHEV EMEAYPCKSQ RGSITSIRSQ PVGTCSSLRV PPESLHVAVR SPGREGWHRW
     KVLPPHVVPR SPTLSKLLCR QEAVRTDSVD GHPPDPKDNL QAERGEMPPS PKHPQRTLTP
     SPLHPAASSL PGSPPRSPPT SPHRHPSLTR KHPCSQRGVP SPTESPPSPQ GCLLEPSDLA
     DEEVRHINSS AKDWGEHSEA GSCSTSPFVS PAASPVPLKN CSTSSLTAGS GKERDLKKFY
     SIDTKGFLTK PSWADDQRRH SIEICPSVRD GDCGFEERAE EKPRSPAHVQ PESEYIHGAR
     RKKKMSPPCI SIDPPMEDDS GAASRTKPSE NSMLRRRTPS CEFPAYREPL EPAEAQPGEP
     GCKAERRAQH LAIPGFSFEQ SDGGGSLSSL SDLLDSGRST PDCELRKPEP LKTQRSNAEK
     SKELLSVAKS PVRMQDLVTV ATEEDIDEPV
//
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