ID F1RA83_DANRE Unreviewed; 300 AA.
AC F1RA83; A0A8M2BAM2;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Cytokine receptor family member B16 {ECO:0000313|Ensembl:ENSDARP00000090421, ECO:0000313|RefSeq:XP_005163304.1};
GN Name=crfb16 {ECO:0000313|Ensembl:ENSDARP00000090421,
GN ECO:0000313|RefSeq:XP_005163304.1,
GN ECO:0000313|ZFIN:ZDB-GENE-071120-9};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000090421};
RN [1] {ECO:0000313|Ensembl:ENSDARP00000090421}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000090421};
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000090421, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000090421};
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [3] {ECO:0000313|RefSeq:XP_005163304.1}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|RefSeq:XP_005163304.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CU467941; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005163304.1; XM_005163247.4.
DR STRING; 7955.ENSDARP00000090421; -.
DR PaxDb; 7955-ENSDARP00000090421; -.
DR Ensembl; ENSDART00000099647; ENSDARP00000090421; ENSDARG00000075181.
DR Ensembl; ENSDART00000099647.6; ENSDARP00000090421.3; ENSDARG00000075181.6.
DR GeneID; 100174902; -.
DR AGR; ZFIN:ZDB-GENE-071120-9; -.
DR CTD; 100174902; -.
DR ZFIN; ZDB-GENE-071120-9; crfb16.
DR eggNOG; ENOG502S2V6; Eukaryota.
DR OMA; QGEYERY; -.
DR OrthoDB; 5354301at2759; -.
DR Reactome; R-DRE-8854691; Interleukin-20 family signaling.
DR Proteomes; UP000000437; Chromosome 2.
DR Bgee; ENSDARG00000075181; Expressed in zone of skin and 7 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004896; F:cytokine receptor activity; IBA:GO_Central.
DR GO; GO:0042015; F:interleukin-20 binding; IBA:GO_Central.
DR GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:GO_Central.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR PANTHER; PTHR20859:SF48; INTERLEUKIN-20 RECEPTOR SUBUNIT BETA; 1.
DR Pfam; PF01108; Tissue_fac; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_005163304.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..300
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041197072"
FT TRANSMEM 220..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 10..111
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF01108"
SQ SEQUENCE 300 AA; 33776 MW; 025DF82171AAF7E0 CRC64;
MCSGLIDSLF LLLLYFSIHH SASLSTYLNI SMHSVNMKHI LKWSQLQTAC STFNHTVQFQ
GEYELHKLNG SWVDAYDCQE IRENRCDLTH DLASNSDYSI RIKTNCDGQK SWTQLPKTFN
RKDTVLLTPE MIVNVEGDPI QVGFNTTLSA ITVKLKVWTE GDEQNALTDM TRAYPYHFSI
AAHRGKEKMC FRAEALVDAI NKSCSTDTQC VIMHKQTSDM PVIVSVAVVI ALAVAFILGW
SVTRFSPQIK HIICHREPIP SALLNNCPAR APNLFTVSSE PTEPLLVLVP TLVQMETNER
//
