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Database: UniProt
Entry: F1RD98_DANRE
LinkDB: F1RD98_DANRE
Original site: F1RD98_DANRE 
ID   F1RD98_DANRE            Unreviewed;       803 AA.
AC   F1RD98;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 2.
DT   25-OCT-2017, entry version 55.
DE   SubName: Full=Si:ch73-193i2.2 {ECO:0000313|Ensembl:ENSDARP00000042874};
DE   Flags: Fragment;
GN   Name=si:ch73-193i2.2 {ECO:0000313|Ensembl:ENSDARP00000042874,
GN   ECO:0000313|ZFIN:ZDB-GENE-141215-32};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000042874, ECO:0000313|Proteomes:UP000000437};
RN   [1] {ECO:0000313|Ensembl:ENSDARP00000042874}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000042874};
RG   Ensembl;
RL   Submitted (JUN-2011) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000042874, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000042874,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSDARP00000042874}.
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DR   EMBL; CU570981; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 7955.ENSDARP00000042874; -.
DR   PaxDb; F1RD98; -.
DR   Ensembl; ENSDART00000042875; ENSDARP00000042874; ENSDARG00000031278.
DR   ZFIN; ZDB-GENE-141215-32; si:ch73-193i2.2.
DR   eggNOG; KOG4177; Eukaryota.
DR   eggNOG; COG0666; LUCA.
DR   GeneTree; ENSGT00900000140984; -.
DR   InParanoid; F1RD98; -.
DR   OMA; KHVRAFR; -.
DR   OrthoDB; EOG091G098K; -.
DR   TreeFam; TF332452; -.
DR   Proteomes; UP000000437; Chromosome 13.
DR   Bgee; ENSDARG00000031278; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   CDD; cd00204; ANK; 2.
DR   Gene3D; 1.25.40.20; -; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR024862; TRPV.
DR   PANTHER; PTHR10582; PTHR10582; 3.
DR   Pfam; PF12796; Ank_2; 2.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 5.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 4.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023,
KW   ECO:0000256|SAAS:SAAS00933366}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    364    387       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    399    417       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    477    498       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    510    526       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    550    572       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    611    636       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      114    270       ANK_REP_REGION. {ECO:0000259|PROSITE:
FT                                PS50297}.
FT   REPEAT      134    168       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   REPEAT      169    201       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   REPEAT      205    237       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   REPEAT      238    270       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   COILED      755    782       {ECO:0000256|SAM:Coils}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSDARP00000042874}.
FT   NON_TER     803    803       {ECO:0000313|Ensembl:ENSDARP00000042874}.
SQ   SEQUENCE   803 AA;  91902 MW;  F2AA0763FFB8B8B8 CRC64;
     XKRFGADEPE NLELQLTDGA RQSVVVSPVS VASVKDVGRS VALLASYARG RWKHAARKTV
     RKKPTEEYIG KYKGLATDED AVDGQRNGKM EMNKRLLDHF RVLAASNKDS DEVDLQLLNE
     ALTHGADPNT ADKYGQTALH EVNISRTWNV DVMRFFLERG ADFQRADAFG VTPLHVAAAL
     DYEEMLQFLL ERGGVSDIEA RTYKDKQTPL HFAAKNDAVA SVRMLLQNGA DITVRDYKDR
     TPLQLAANFD RSETARLLLE FGADAGVQDS DGHLCITAMI TKMTPVADLA MNQFHVKDRM
     ARQQFYYLHL MEPQTADKTS PKGSDPSSPL EFIVNLGKLD LIMHPVVLKL ITVKWNLYGR
     MGAWILLLLN FLFIVSWTTV AISVSVRPDG DRYDLPGDWW RVLLVVLALV LTVTEVYREV
     MEIVRSRRKL KHWQRWTVQK INEDLSCSHP MWPEERNYLE GQIKYIRNMK GTYAQDLWNI
     FDWLVYLLLL AVLGIHLADI FLVSDLLRLN SLRLFAVSII FLWLRLMKHV RAFRAMGPFI
     VMLGKIAGDV LRFLFLYIEI YVPFACAFWI IFGGLEDVPS METVPRLLYS LYRITLVDDY
     EFDEMLEVDT VMAYLLCGTF LALSAILCVN LLIALLSDTF QRVYDNALAN AVMQQAAIIL
     QIEESMPCLR RCYDKEHIHR NCAPLGEFYD DDVTINPEKH AEMKKLTEQI KDTLDRHLDI
     QREMISPQFA FAGPRDVTRK RNASHPEKEA HLKTLSRLEK DQQKYSQDLS ELKAEVKELH
     SLLLKLTSVT DDHDDDKKLS VRA
//
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