ID F1RNN6_PIG Unreviewed; 486 AA.
AC F1RNN6;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Galactose-3-O-sulfotransferase 4 {ECO:0000313|EMBL:HCZ86476.1, ECO:0000313|Ensembl:ENSSSCP00000008169.2};
GN Name=GAL3ST4 {ECO:0000313|Ensembl:ENSSSCP00000008169.2,
GN ECO:0000313|VGNC:VGNC:88323};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000008169.2, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000008169.2, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000008169.2,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:HCZ86476.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=30723633; DOI=.7717/peerj.6374;
RA Gilbert D.G.;
RT "Genes of the pig, Sus scrofa, reconstructed with EvidentialGene.";
RL PeerJ 7:E6374-E6374(2019).
RN [3] {ECO:0000313|Ensembl:ENSSSCP00000008169.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the galactose-3-O-sulfotransferase family.
CC {ECO:0000256|ARBA:ARBA00008124}.
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DR EMBL; DQIR01031001; HCZ86476.1; -; Transcribed_RNA.
DR RefSeq; XP_005661947.1; XM_005661890.2.
DR RefSeq; XP_013850866.1; XM_013995412.1.
DR PaxDb; 9823-ENSSSCP00000008169; -.
DR Ensembl; ENSSSCT00000008388.5; ENSSSCP00000008169.2; ENSSSCG00000007648.5.
DR GeneID; 100511123; -.
DR KEGG; ssc:100511123; -.
DR CTD; 79690; -.
DR VGNC; VGNC:88323; GAL3ST4.
DR eggNOG; ENOG502QSHR; Eukaryota.
DR GeneTree; ENSGT00950000182923; -.
DR HOGENOM; CLU_040616_1_2_1; -.
DR OMA; RTMRLWG; -.
DR OrthoDB; 3032344at2759; -.
DR TreeFam; TF314802; -.
DR Proteomes; UP000008227; Chromosome 3.
DR Bgee; ENSSSCG00000007648; Expressed in forelimb bud and 38 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0001733; F:galactosylceramide sulfotransferase activity; IEA:InterPro.
DR GO; GO:0009247; P:glycolipid biosynthetic process; IEA:InterPro.
DR GO; GO:0009101; P:glycoprotein biosynthetic process; IEA:Ensembl.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR009729; Gal-3-0_sulfotransfrase.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR14647; GALACTOSE-3-O-SULFOTRANSFERASE; 1.
DR PANTHER; PTHR14647:SF57; GALACTOSE-3-O-SULFOTRANSFERASE 4; 1.
DR Pfam; PF06990; Gal-3-0_sulfotr; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW Transferase {ECO:0000313|EMBL:HCZ86476.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 222..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 486 AA; 54279 MW; D58EE2CC36D54873 CRC64;
MGHLSSTRTM RLWGPRSLGV ALGVFMTIGF ALQFWGGPFQ RRLPGLQLRQ SWAPSPGLAL
PSCSPRQRLV FLKTHKSGSS SVLSLLHRYG DRHGLRFALP ARYQFGYPRL FEASRVKGYR
PQGGGTQPPF HILCHHMRFN LKEVLQVMPS DSFFFSIVRD PAALTRSAFS YYKSTSSAFR
KAPSLAAFLA NPRAFYRPGA RGDHYARNLL WFDFGLPFPP EMRTKRGNPR PPRDPKAPQL
RVLPSGAGPP AHTLDPNALF HPVPTLADGH SRTSSPASSD LGSSSFIQWS LAWLDSVFDL
VLVAEYFDES LVLLADALCW GLDDVVGFMH NAQAGGRQSG SAVSDDGLTA EDRQLTARAR
AWNNLDWALY VHFNHSLWER IKQYGQSRLD SAVAELRARR EALAKHCLVG GEALDPKYIT
DRRFRPFQFG SGKVLGYVLR SGLSLQDQEE CERLATPELQ YKDKLDAKQF PPTVSLPLKN
SRLSSP
//
