ID F1RRQ0_PIG Unreviewed; 680 AA.
AC F1RRQ0;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2022, sequence version 5.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=MTSS I-BAR domain containing 1 {ECO:0000313|Ensembl:ENSSSCP00000006383.5};
GN Name=MTSS1 {ECO:0000313|Ensembl:ENSSSCP00000006383.5,
GN ECO:0000313|VGNC:VGNC:90474};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000006383.5, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000006383.5, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000006383.5,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000006383.5}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F1RRQ0; -.
DR Ensembl; ENSSSCT00000006558.6; ENSSSCP00000006383.5; ENSSSCG00000005975.6.
DR VGNC; VGNC:90474; MTSS1.
DR GeneTree; ENSGT00950000183156; -.
DR TreeFam; TF320619; -.
DR Proteomes; UP000008227; Chromosome 4.
DR Bgee; ENSSSCG00000005975; Expressed in penis and 42 other cell types or tissues.
DR ExpressionAtlas; F1RRQ0; baseline and differential.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR CDD; cd07643; I-BAR_IMD_MIM; 1.
DR CDD; cd22060; WH2_MTSS1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR013606; I-BAR_dom.
DR InterPro; IPR030127; MTSS1/MTSS2.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR15708; ACTIN BUNDLING/MISSING IN METASTASIS-RELATED; 1.
DR PANTHER; PTHR15708:SF10; PROTEIN MTSS 1; 1.
DR Pfam; PF08397; IMD; 1.
DR Pfam; PF02205; WH2; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS51338; IMD; 1.
DR PROSITE; PS51082; WH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 1..254
FT /note="IMD"
FT /evidence="ECO:0000259|PROSITE:PS51338"
FT DOMAIN 652..669
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 260..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 514..680
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..341
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..559
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 581..596
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 610..626
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 680 AA; 73605 MW; 99DAD640DBC0EC7E CRC64;
MEAVIEKECS ALGGLFQTII SDMKGSYPVW EDFINKAGKL QSQLRTTVVA AAAFLDAFQK
VADMATNTRG GTREIGSALT RMCMRHRSIE AKLRQFSSAL IDCLINPLQE QMEEWKKVAN
QLDKDHAKEY KKARQEIKKK SSDTLKLQKK AKKVDALGRG DIQPQLDSAL QDVNDKYLLL
EETEKQAVRK ALIEERGRFC TFISMLRPVI EEEISMLGEI THLQTISEDL KSLTMDPHKL
PSSSEQVILD LKGSDYSWSY QTPPSSPSTT MSRKSSVCSS LNSVNSSDSR SSGSHGSHSH
SPSSHYRYRG SSLAQQAPVR LSSVSSHDSG FISQDAFQSK SPSPMPPEAP NQRRKEKREP
DSSGGGPTAA GGAPAAAEEA QRPRSMTVSA ATRPGEEMEA CEELALALSR GLQLDTQRSS
RDSLQCSSGY STQTTTPCCS EDTIPSQVSD YDYFSVSGDQ EADQQEFDKS STIPRNSDIS
QSYRRMFQAK RPASTAGLPT TLGPAMVTPG VATIRRTPST KPSVRRGTIG AGPIPIKTPV
IPVKTPTVPD LPGVLPAPPD GPEERGEHSP ESPSAGEGPQ GVTGMPSSTW SGQASVNPPL
PGPKPSIPEE HRQAIPESEA EDQERDPPSA TASPGQTAES DPADLSPREA PQGEDMLNAI
RRGVKLKKTT TNDRSAPRFS
//
