ID   F1SC64_PIG              Unreviewed;       837 AA.
AC   F1SC64;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 2.
DT   27-MAR-2024, entry version 73.
DE   SubName: Full=Lymphoid-specific helicase isoform 1 {ECO:0000313|EMBL:HCZ80548.1};
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823 {ECO:0000313|EMBL:HCZ80548.1};
RN   [1] {ECO:0000313|EMBL:HCZ80548.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=30723633; DOI=.7717/peerj.6374;
RA   Gilbert D.G.;
RT   "Genes of the pig, Sus scrofa, reconstructed with EvidentialGene.";
RL   PeerJ 7:E6374-E6374(2019).
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DR   EMBL; DQIR01025073; HCZ80548.1; -; Transcribed_RNA.
DR   RefSeq; XP_003359348.1; XM_003359300.3.
DR   AlphaFoldDB; F1SC64; -.
DR   SMR; F1SC64; -.
DR   STRING; 9823.ENSSSCP00000011175; -.
DR   PaxDb; 9823-ENSSSCP00000011175; -.
DR   PeptideAtlas; F1SC64; -.
DR   GeneID; 100154547; -.
DR   KEGG; ssc:100154547; -.
DR   CTD; 3070; -.
DR   eggNOG; KOG0385; Eukaryota.
DR   HOGENOM; CLU_000315_17_3_1; -.
DR   InParanoid; F1SC64; -.
DR   OMA; PNIFTDW; -.
DR   OrthoDB; 5482994at2759; -.
DR   Bgee; ENSSSCG00000010486; Expressed in hindlimb bud and 44 other cell types or tissues.
DR   ExpressionAtlas; F1SC64; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005721; C:pericentric heterochromatin; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR   GO; GO:0003682; F:chromatin binding; IBA:GO_Central.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006306; P:DNA methylation; IBA:GO_Central.
DR   GO; GO:0006346; P:DNA methylation-dependent heterochromatin formation; IBA:GO_Central.
DR   GO; GO:0046651; P:lymphocyte proliferation; IBA:GO_Central.
DR   GO; GO:0031508; P:pericentric heterochromatin formation; IBA:GO_Central.
DR   CDD; cd18009; DEXHc_HELLS_SMARCA6; 1.
DR   CDD; cd18793; SF2_C_SNF; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR044753; HELLS_N.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038718; SNF2-like_sf.
DR   InterPro; IPR049730; SNF2/RAD54-like_C.
DR   InterPro; IPR000330; SNF2_N.
DR   PANTHER; PTHR47161; LYMPHOID-SPECIFIC HELICASE; 1.
DR   PANTHER; PTHR47161:SF1; LYMPHOID-SPECIFIC HELICASE; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00176; SNF2-rel_dom; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:HCZ80548.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
SQ   SEQUENCE   837 AA;  97012 MW;  1F44F603EC92B4D4 CRC64;
     MPAQQPASSG GSLAPDMVEQ AETAVITPAM LEEEEQLEAA GLERERKMLE KARMSWDRES
     VDIRYRRLQH LLEKSNIYSK FLLTKMEQQQ LEEQKKKEKL ERKKESLKVT KGKNSIDASE
     ENTVMRKKRG REDESYNISE VMSKEEILSV AKKNKKETEN ESSCSNLCVE DLQKNRDSNS
     IIKDRLSQTV RQNTKFFFDP VRKCNGQPVP FQQPKHFTGG VMRWYQVEGM EWLRMLWENG
     INGILADEMG LGKTVQCIAT IALMIQRGVP GPFLVCGPLS TLPNWMAEFQ RFTPEIPTML
     YHGSQQERRK LVNHIHKRKG TLQIHPVVIT SFEIAMRDRN VLQHCYWKYL IVDEGHRIKN
     MKCRLIRELK RFNADNKLLL TGTPLQNNLS ELWSLLNFLL PDVFDDLKSF ESWFDITSLS
     ETAEDIIAKE REQNVLHMLH QILTPFLLRR LKSDVALEVP PKREVVVYAP LSKKQEVFYT
     AIVNRTITNM FGSSEKETVE LSPTGRPKRR TRKSIDYSKI DDFPNELEKL ISQIQPEVDR
     ERAVVETNIP VESEVNLKLQ NIMMLLRKCC NHPYLIEYPI DPVTQEFKID EELVTNSGKF
     LILDRMLPEL KIRGHKVLLF SQMTRMLDIL MDYCHFRNFN FSRLDGSMSY TEREKNMHSF
     NTDPDVFIFL VSTRAGGLGI NLTAADTVII YDSDWNPQSD LQAQDRCHRI GQTKPVVVYR
     LVTANTIDQK IVERAAAKRK LEKLIIHKNH FKGGQSGLNQ SKNFLDPKEL MELLKSRDYE
     REVKGSREKV ISDKDLELLL DRSDLIDQMN ASGPIKEKMG IFKILENSED SSPDCLF
//