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Database: UniProt
Entry: F1SF76_PIG
LinkDB: F1SF76_PIG
Original site: F1SF76_PIG 
ID   F1SF76_PIG              Unreviewed;       691 AA.
AC   F1SF76;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   30-AUG-2017, entry version 43.
DE   SubName: Full=Potassium voltage-gated channel subfamily Q member 4 {ECO:0000313|Ensembl:ENSSSCP00000004297};
GN   Name=KCNQ4 {ECO:0000313|Ensembl:ENSSSCP00000004297};
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;
OC   Sus.
OX   NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000004297, ECO:0000313|Proteomes:UP000008227};
RN   [1] {ECO:0000313|Ensembl:ENSSSCP00000004297, ECO:0000313|Proteomes:UP000008227}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000004297};
RG   Porcine genome sequencing project;
RL   Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSSCP00000004297}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAY-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSSSCP00000004297}.
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DR   EMBL; CU466467; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9823.ENSSSCP00000004297; -.
DR   PaxDb; F1SF76; -.
DR   Ensembl; ENSSSCT00000004397; ENSSSCP00000004297; ENSSSCG00000003975.
DR   eggNOG; KOG1419; Eukaryota.
DR   eggNOG; COG1226; LUCA.
DR   GeneTree; ENSGT00550000074513; -.
DR   InParanoid; F1SF76; -.
DR   OMA; WAFVYHV; -.
DR   OrthoDB; EOG091G02ZT; -.
DR   TreeFam; TF315186; -.
DR   Reactome; R-SSC-1296072; Voltage gated Potassium channels.
DR   Proteomes; UP000008227; Chromosome 6.
DR   Bgee; ENSSSCG00000003975; -.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:GO_Central.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:GO_Central.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR   InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR   InterPro; IPR015573; KCQN4.
DR   InterPro; IPR028325; VG_K_chnl.
DR   PANTHER; PTHR11537; PTHR11537; 1.
DR   PANTHER; PTHR11537:SF214; PTHR11537:SF214; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF03520; KCNQ_channel; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01459; KCNQCHANNEL.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008227};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00788393, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00793138,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00789957,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268}.
FT   TRANSMEM     95    117       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    129    149       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    170    195       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    235    254       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    295    320       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       96    320       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      460    641       KCNQ_channel. {ECO:0000259|Pfam:PF03520}.
SQ   SEQUENCE   691 AA;  76718 MW;  4FABAED12291CAEF CRC64;
     AEPRGLEGTK GPPPKLEGAG QAPRPSQPER GLQGGTSPRF LGLLGSLLPP GAPLPGPGPG
     PGSACGQRSS AAHKRYRRLQ NWVYNVLERP RGWAFVYHVF IFLLVFSCLV LSVLSTIQEH
     QELANECLLI LEFVMIVVFG LEYIVRVWSA GCCCRYRGWQ GRFRFARKPF CVIDFIVFVA
     SVAVIAAGTQ GNIFATSALR SMRFLQILRM VRMDRRGGTW KLLGSVVYAH SKELITAWYI
     GFLVLIFASF LVYLAEKDAN SDFSSYADSL WWGTITLTTI GYGDKTPHTW LGRVLAAGFA
     LLGISFFALP AGILGSGFAL KVQEQHRQKH FEKRRMPAAN LIQAAWRLYS TDTSRAYLTA
     TWYYYDSILP SFRELALLFE HVQRARNGGL RPLEVRRAPV PDGAPSRYPP VATCHRPGSA
     SFCPGESSRM GIKDRIRMGS SQRRTGPSKQ HLAPPPMPAS PSSEQVGEAS SPTKVQKSWS
     FNDRTRFRAS LRLKPRTSAE EGPSEEAAEE KSYQSELTVD DVMPAVKTVI RSVRILKFLV
     AKRKFKETLR PYDVKDVIEQ YSAGHLDMLG RIKSLQARVD QIVGRGPGDR KAREKSDKGP
     SDMEAVDEIS MMGRVVKVEK QVQSIEHKLD LLLGFYSRCL RPGTSASLGA VQVPLFDPDT
     TSDYHSPVDH EDLSVSAQTL SISRSVSTNM D
//
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