ID F1SJP2_PIG Unreviewed; 896 AA.
AC F1SJP2;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 4.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Trafficking kinesin protein 1 {ECO:0000313|Ensembl:ENSSSCP00000012024.4};
GN Name=TRAK1 {ECO:0000313|Ensembl:ENSSSCP00000012024.4,
GN ECO:0000313|VGNC:VGNC:94369};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000012024.4, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000012024.4, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000012024.4,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000012024.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC -!- SIMILARITY: Belongs to the milton family.
CC {ECO:0000256|ARBA:ARBA00007007}.
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DR AlphaFoldDB; F1SJP2; -.
DR Ensembl; ENSSSCT00000012347.5; ENSSSCP00000012024.4; ENSSSCG00000011278.5.
DR VGNC; VGNC:94369; TRAK1.
DR GeneTree; ENSGT00940000155697; -.
DR HOGENOM; CLU_013450_0_0_1; -.
DR TreeFam; TF323495; -.
DR Proteomes; UP000008227; Chromosome 13.
DR Bgee; ENSSSCG00000011278; Expressed in heart left ventricle and 41 other cell types or tissues.
DR ExpressionAtlas; F1SJP2; baseline and differential.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR InterPro; IPR006933; HAP1_N.
DR InterPro; IPR022154; TRAK1/2_C.
DR PANTHER; PTHR15751; TRAFFICKING KINESIN-BINDING PROTEIN; 1.
DR PANTHER; PTHR15751:SF11; TRAFFICKING KINESIN-BINDING PROTEIN 1; 1.
DR Pfam; PF04849; HAP1_N; 1.
DR Pfam; PF12448; Milton; 1.
DR SMART; SM01424; HAP1_N; 1.
DR SMART; SM01423; Milton; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 9..295
FT /note="HAP1 N-terminal"
FT /evidence="ECO:0000259|SMART:SM01424"
FT DOMAIN 356..525
FT /note="Trafficking kinesin-binding protein C-terminal"
FT /evidence="ECO:0000259|SMART:SM01423"
FT REGION 413..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 717..740
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 54..109
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 198..295
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 896 AA; 99198 MW; 8E03D6919401EDFF CRC64;
MSLRDLGGEE ECFEYDCQDE ETKPTHEQPE TLDLLEEVLC AERVGQMTKT YNDIDAVTRL
LEEKERDLEL AARIGQSLLK KNKTLTERNE LLEEQVEHIR EEVSQLRHEL SMKDELLQFY
TSAAEESEPE SVCSTPLKRN ESSSSVQNYF HLDSLQKKLK DLEEENVVLR SEACQLKTET
ITYEEKEQQL VNDCVKELRD ANVQIASISE ELAKKTEDAA RQQEEITHLL SQIVDLQKKA
KACAVENEEL VQHLGAAKDA QRQLTAELRE LEDKYAECME MLHEAQEELK NLRNKTMPNT
TSRRYHSLGL FPMDSLAAEI EGTMRKELQL EEPESPDIAH QKRVFETVRN INQVVKQRSL
TPSPMNIPGS NQSSAMNSLL SSCVSTPRSS FYGSDVGNVV LDNKTNSIIL EAESADLGNG
ERSKKPGTPG TPGSHDLETA LRRLSLRREN YLSERRFFEE EQERKLRELA EKGELLSGSL
TPTESIMSLG THSRFSEFTG FSGMSFSSRS YLPEKLQIVK PLEGSATLHH WQQLAQPHLG
GILDPRPGVV TKGFRTLDVD LDEVYCLNDF EEDDTGDHIS LPGLATSTPV QHPETSAHHP
GKCMSQTNST FTFTTCRILH PSDELTRVTP SLNSAPTPAC GSASHLKSTP VATPCTPRRL
SLAESFTNVR ESTTTMSTSL GLVWLLKERG ISAAVYDPQS WDRAGRGSLL RSGTPRMAVI
PSTPPNSPMQ TPTSSSPSFE FKCTSPPYDN FLASKPASSI LREVREKKVV RSSESQTDVS
VSNLNLVDKV RRFGVAKVVN SGRAHVPTLT EDQGPLLCGP PGPAQALVPG GLVPEGLPLG
CPTVTSAIGG LQLNSGIRRN RSFPTMVGSS MQMKAPVTLT SGILMGAKLP KQTSLR
//
