ID F1SJQ3_PIG Unreviewed; 355 AA.
AC F1SJQ3;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2022, sequence version 4.
DT 27-MAR-2024, entry version 85.
DE RecName: Full=Neuronal-specific septin-3 {ECO:0000256|ARBA:ARBA00041105};
GN Name=SEPTIN3 {ECO:0000313|Ensembl:ENSSSCP00000000042.4,
GN ECO:0000313|VGNC:VGNC:92722};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000000042.4, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000000042.4, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000000042.4,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000000042.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. Septin GTPase family.
CC {ECO:0000256|RuleBase:RU004560}.
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DR AlphaFoldDB; F1SJQ3; -.
DR PeptideAtlas; F1SJQ3; -.
DR Ensembl; ENSSSCT00000000042.5; ENSSSCP00000000042.4; ENSSSCG00000000040.5.
DR VGNC; VGNC:92722; SEPTIN3.
DR GeneTree; ENSGT00940000158004; -.
DR HOGENOM; CLU_017718_7_1_1; -.
DR TreeFam; TF101078; -.
DR Proteomes; UP000008227; Chromosome 5.
DR Bgee; ENSSSCG00000000040; Expressed in cerebellum and 38 other cell types or tissues.
DR ExpressionAtlas; F1SJQ3; baseline and differential.
DR Genevisible; F1SJQ3; SS.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd01850; CDC_Septin; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR030379; G_SEPTIN_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016491; Septin.
DR InterPro; IPR008114; Septin3.
DR PANTHER; PTHR18884:SF62; NEURONAL-SPECIFIC SEPTIN-3; 1.
DR PANTHER; PTHR18884; SEPTIN; 1.
DR Pfam; PF00735; Septin; 1.
DR PIRSF; PIRSF006698; Septin; 1.
DR PRINTS; PR01741; SEPTIN3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51719; G_SEPTIN; 1.
PE 1: Evidence at protein level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU004560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004560};
KW Proteomics identification {ECO:0007829|PeptideAtlas:F1SJQ3};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 57..330
FT /note="Septin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51719"
SQ SEQUENCE 355 AA; 40449 MW; D5C35349641DA48D CRC64;
FAGLPEARTD TAMSELVPEP RPKPAVPMKP VSINSSLLGY IGIDTIIEQM RKKTMKTGFD
FNIMVVGQSG LGKSTLVNTL FKSQVSRKAS SWNREEKIPK TVEIKAIGHV IEEGGVKMKL
TVIDTPGFGD QINNENCWEP IEKYINEQYE KFLKEEVNIA RKKRIPDTRV HCCLYFISPT
GHSLRPLDLE FMKHLSKVVN IIPVIAKADT MTLEEKSEFK QRVRKELEVN GIEFYPQKEF
DEDLEDKTEN DKIRQESMPF AVVGSDKEYQ VNGKRVLGRK TPWGIIEVEN LNHCEFALLR
DFVIRTHLQD LKEVTHNIHY ETYRAKRLND NGGLPPCFEA VSGCGSLLPT AARRI
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