ID   F1ST51_PIG              Unreviewed;      1671 AA.
AC   F1ST51;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2022, sequence version 5.
DT   27-MAR-2024, entry version 75.
DE   SubName: Full=Coiled-coil domain containing 180 {ECO:0000313|Ensembl:ENSSSCP00000005757.5};
GN   Name=CCDC180 {ECO:0000313|Ensembl:ENSSSCP00000005757.5};
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000005757.5, ECO:0000313|Proteomes:UP000008227};
RN   [1] {ECO:0000313|Ensembl:ENSSSCP00000005757.5, ECO:0000313|Proteomes:UP000008227}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000005757.5,
RC   ECO:0000313|Proteomes:UP000008227};
RG   Porcine genome sequencing project;
RL   Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSSCP00000005757.5}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   STRING; 9823.ENSSSCP00000005757; -.
DR   PaxDb; 9823-ENSSSCP00000024046; -.
DR   PeptideAtlas; F1ST51; -.
DR   Ensembl; ENSSSCT00000005904.5; ENSSSCP00000005757.5; ENSSSCG00000045508.2.
DR   eggNOG; KOG2039; Eukaryota.
DR   GeneTree; ENSGT00940000153246; -.
DR   HOGENOM; CLU_283554_0_0_1; -.
DR   InParanoid; F1ST51; -.
DR   Proteomes; UP000008227; Chromosome 1.
DR   Bgee; ENSSSCG00000045508; Expressed in testis and 46 other cell types or tissues.
DR   InterPro; IPR028089; DUF4455.
DR   InterPro; IPR027914; DUF4456.
DR   PANTHER; PTHR21444; COILED-COIL DOMAIN-CONTAINING PROTEIN 180; 1.
DR   PANTHER; PTHR21444:SF14; COILED-COIL DOMAIN-CONTAINING PROTEIN 180; 1.
DR   Pfam; PF14643; DUF4455; 1.
DR   Pfam; PF14644; DUF4456; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT   DOMAIN          175..641
FT                   /note="DUF4455"
FT                   /evidence="ECO:0000259|Pfam:PF14643"
FT   DOMAIN          1361..1562
FT                   /note="DUF4456"
FT                   /evidence="ECO:0000259|Pfam:PF14644"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          649..732
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          744..811
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1220..1244
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          538..578
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1481..1515
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        717..732
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        756..770
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        780..811
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1671 AA;  194645 MW;  367C0530FD295E62 CRC64;
     REGGSRRWVP PRVRAQGPRL GSRPSLNTIP EQWLPCRGVQ PEAKMSSVGK VTQIPSGKVY
     QQIFEAEVQL VRSLASTRKR AAECSMTPKD GRKPLMKKTD IREGEMLSPR QQKWAHSLPN
     DWVTENPVLL REKEIAKKEK AQESENTIAA REVRGLMDTI VPERIRTITL EGRGDYKRRG
     YESALGSFKE EIAQIGMEME PLILEPGALL LKKLAEYDKD INSLFEKVEN NSNLEDYTIQ
     TLLELWDQVA KKFLLQKQEI KDLDKTLHSL EFSRADKLKS VMKKYVQIIE KTSYLMQPDV
     YRLINKEAMI INHALLGNRR ALAQLFVNLM EATLQQELNG HRRWQGLVDA WKSLKMEDLV
     QGFSEFMASE KIQMPPAVKT ELETMLKNQS ALQQKRLDHL CTICDLLPPN YSKAQLTEWH
     SSLDSLNKHL DAYHMDCMMR IHVQYEKTWQ ECLAEVQKCK KQLLDWKAFT EEEAESLVSP
     SFFQMVGSLQ RKVEAELEVL DKSFEALAKQ TEQQSLDLFS YFQEAVQLWE AHQSLLLMQE
     LELEKRIEQQ RQKHSQENQA QEAHLDKLLD QLRQQSSEDT LKFHLEKAKD YLKNMRCRYE
     SFHGLLTKEV MEYPVIILKE LNSYSSTLSR YFCVREVFEQ VWKGTQKTKP HEKQFRERVR
     KLRGKREPKV DVSKGEESVS RGTSSLRPAE ETEEEEDQEI EFPTNQKVAV SPQKESVLSE
     EMDESREDSS PGLEEMWVEA DSFLKSPLSQ ETVTVQEEEK EEDKEEKEEE EKEETKEKVE
     EEREEEEEEE QKEEEEEEEE EEREESLGEV TQEDMEFFTT SSGNTYFVFL PLEQEESITK
     PHCSFSTVLL NDASGAKVLE QVIIPSRLIL EIKKQIRAGF FEHLEKWFDQ CALNAQVTVA
     TKIDQLDSEL ELRLHLHQPR AQRIEKDIHN VRAAELLLHQ ERLDSHCAGV TETLRKERMM
     FCQFQEEQNT RSKNFRRKIY DMEHIFLNAT KSQKLVILSS TLHRELLSYV DVIQVSLRSF
     RQYLEESLGK LRYTNVEFVK HCRLFSEGGN FSSEEIDSLC HRLEKEAARI EFVESLIMIN
     MEKMESEYLD QANEVINKFE SKFHNLSVDL LFIEKIQRLL TNLQVNIKCE VAKSNLQTDG
     LNSSLEQLQS KVQMCRSSRG DKEIVTSEDL LGLVRTWKEK LSQRIQYLNC KLDMVSVTQV
     VFTDILTDVE VESDILVSSE AQEEEAKGDV VTPESLAQPS RMGKSMVEDP AVEVVKRILF
     PDAKCSTQRC DKDPSSPWIH CSCPGCSSAK AFKRHQSRGD HSVKKDLVVA SATSAASTTR
     YLKPNRLERK YQVLGDKPPP LAEAGWRMPA SWARAPTLSD LLQEFYRKEK RAVTRPDCMY
     ETFDQCAENI SKKILEYHSQ TDEYYNSCLI ELRAQMRRFE ELLPQVCWQV TENFKEHHWK
     KFCASTKEIR EQFWTSHEEL ERRKDENARK LRPNLGHPAH LQEMESLCQA EEKRQEDLDT
     LIEATRENLE EFTRKYCRFF IASLATFTEK FLLQLDEVVT IDDVQVAKME PPKQKTSILI
     RRKLAGLSLE EESEKPLIER GSRKWPGLKP TEVTIQNKIL LRKTSSITTA KTTLGHLASV
     EARDAVYLKY LASFEKELKK IQEDNTLQVR EAQRWKDNWK RSVHTIQDLY L
//