ID F1VX33_9BURK Unreviewed; 78 AA.
AC F1VX33;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=RNA-binding protein Hfq {ECO:0000256|HAMAP-Rule:MF_00436};
GN Name=hfq {ECO:0000256|HAMAP-Rule:MF_00436};
GN ORFNames=IMCC9480_1795 {ECO:0000313|EMBL:EGF32837.1};
OS Oxalobacteraceae bacterium IMCC9480.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae.
OX NCBI_TaxID=937450 {ECO:0000313|EMBL:EGF32837.1, ECO:0000313|Proteomes:UP000004494};
RN [1] {ECO:0000313|EMBL:EGF32837.1, ECO:0000313|Proteomes:UP000004494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMCC9480 {ECO:0000313|EMBL:EGF32837.1,
RC ECO:0000313|Proteomes:UP000004494};
RX PubMed=21572000; DOI=10.1128/JB.05088-11;
RA Oh H.M., Lee K., Jang Y., Kang I., Kim H.J., Kang T.W., Kim S.Y., Cho J.C.;
RT "Genome sequence of strain IMCC9480, a xanthorhodopsin-bearing
RT betaproteobacterium isolated from the Arctic Ocean.";
RL J. Bacteriol. 193:3421-3421(2011).
CC -!- FUNCTION: RNA chaperone that binds small regulatory RNA (sRNAs) and
CC mRNAs to facilitate mRNA translational regulation in response to
CC envelope stress, environmental stress and changes in metabolite
CC concentrations. Also binds with high specificity to tRNAs.
CC {ECO:0000256|HAMAP-Rule:MF_00436}.
CC -!- SUBUNIT: Homohexamer. {ECO:0000256|HAMAP-Rule:MF_00436}.
CC -!- SIMILARITY: Belongs to the Hfq family. {ECO:0000256|HAMAP-
CC Rule:MF_00436}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGF32837.1}.
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DR EMBL; AEPR01000155; EGF32837.1; -; Genomic_DNA.
DR AlphaFoldDB; F1VX33; -.
DR OrthoDB; 9799751at2; -.
DR Proteomes; UP000004494; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01716; Hfq; 1.
DR Gene3D; 2.30.30.100; -; 1.
DR HAMAP; MF_00436; Hfq; 1.
DR InterPro; IPR005001; Hfq.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR047575; Sm.
DR NCBIfam; TIGR02383; Hfq; 1.
DR PANTHER; PTHR34772; RNA-BINDING PROTEIN HFQ; 1.
DR PANTHER; PTHR34772:SF1; RNA-BINDING PROTEIN HFQ; 1.
DR Pfam; PF17209; Hfq; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR PROSITE; PS52002; SM; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000004494};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00436};
KW Stress response {ECO:0000256|ARBA:ARBA00023016, ECO:0000256|HAMAP-
KW Rule:MF_00436}.
FT DOMAIN 10..69
FT /note="Sm"
FT /evidence="ECO:0000259|PROSITE:PS52002"
SQ SEQUENCE 78 AA; 8791 MW; 9925273D2FEC69E4 CRC64;
MSNKGQMLQD PFLNALRKEH VPVSIYLVNG IKLQGHIESF DQYVVLLRNT VTQMVYKHAI
STVVPARAVT LNLEPEAD
//
