ID F2BWM2_9FIRM Unreviewed; 677 AA.
AC F2BWM2;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Type III restriction system methylase {ECO:0000313|EMBL:EGF14889.1};
DE EC=2.1.1.72 {ECO:0000313|EMBL:EGF14889.1};
GN Name=mod {ECO:0000313|EMBL:EGF14889.1};
GN ORFNames=HMPREF9083_0589 {ECO:0000313|EMBL:EGF14889.1};
OS Dialister micraerophilus DSM 19965.
OC Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC Dialister.
OX NCBI_TaxID=888062 {ECO:0000313|EMBL:EGF14889.1, ECO:0000313|Proteomes:UP000003503};
RN [1] {ECO:0000313|EMBL:EGF14889.1, ECO:0000313|Proteomes:UP000003503}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19965 {ECO:0000313|EMBL:EGF14889.1,
RC ECO:0000313|Proteomes:UP000003503};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGF14889.1}.
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DR EMBL; AFBB01000009; EGF14889.1; -; Genomic_DNA.
DR AlphaFoldDB; F2BWM2; -.
DR STRING; 888062.HMPREF9083_0589; -.
DR eggNOG; COG2189; Bacteria.
DR HOGENOM; CLU_020164_2_1_9; -.
DR Proteomes; UP000003503; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-EC.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR002295; N4/N6-MTase_EcoPI_Mod-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR PIRSF; PIRSF015855; TypeIII_Mtase_mKpnI; 1.
DR PRINTS; PR00506; D21N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EGF14889.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003503};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EGF14889.1}.
FT DOMAIN 133..467
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
SQ SEQUENCE 677 AA; 78769 MW; 37E637D0DC9DC7B7 CRC64;
MYKKGIKMEN TNVEQMKMQT KNLADEKLEA LKELFPNAVT EVIDENGEET VAIDKDILMQ
EISAKVVEGN EERYQFTWPD KKKSILAANA PTTKTLRPCK EESVNFDTTE NLYIEGDNLE
VLKLLQETYL GKIKMIYIDP PYNTGNNILY KNDFSIPKEE YIDLSNQKDA YGNFLFQNTE
SNGRFHTDWL NIMYPRLKLA RNLLKDEGYI AIAIDDNEVY NLKKIMDEIF GEKNYIGTII
IRSNPQGRNK DNIDPVHEYH LVYSRNYTKM PLLKIGKRNA KIDSFENLMR TGKNSRKYER
PYRFYPVLVK NEKIEMITDE EYKKIYAENC EFNEEYIEYL REKYEGNGYK FILPLSKNGE
EKVWQREFSR VKKEYRTYRF IGNKVKRPPE QTRTPASLWY DDIYSNVSKG TNSLKKIFND
KIIFDFSKSL YTVRDLISLN SEDEDIILDF FSGSATTAHA TMQLNAEDGG NRKFILVQLP
ENLDESLKKA NDNAKKTIEN AIKFLDSINR PHLLTEIGKE RIRRAGKKIL EENKDKEGIE
NLDTGFRVLK VDSSNMKDVY YAPQELNKKD VFSYVDNIKE DRSSMDLLFQ VMLDLGISLS
SKIEEKDISG KKVFTVDGNF LIACFDSDID DEVINNIAEK KPVFAVFKNK SFTKDSPLAN
LEEIFKTVSP DTVRKVL
//
