ID F2CFU1_STRSA Unreviewed; 314 AA.
AC F2CFU1;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=CorA family magnesium transporter {ECO:0000313|EMBL:EGF18210.1};
GN ORFNames=HMPREF9391_1518 {ECO:0000313|EMBL:EGF18210.1};
OS Streptococcus sanguinis SK408.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=888818 {ECO:0000313|EMBL:EGF18210.1, ECO:0000313|Proteomes:UP000004826};
RN [1] {ECO:0000313|EMBL:EGF18210.1, ECO:0000313|Proteomes:UP000004826}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK408 {ECO:0000313|EMBL:EGF18210.1,
RC ECO:0000313|Proteomes:UP000004826};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGF18210.1}.
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DR EMBL; AFBE01000010; EGF18210.1; -; Genomic_DNA.
DR RefSeq; WP_002918085.1; NZ_GL878562.1.
DR AlphaFoldDB; F2CFU1; -.
DR PATRIC; fig|888818.3.peg.1479; -.
DR HOGENOM; CLU_007127_8_1_9; -.
DR Proteomes; UP000004826; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR CDD; cd12827; EcCorA_ZntB-like_u2; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR InterPro; IPR047199; CorA-like.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR PANTHER; PTHR47891:SF2; MAGNESIUM AND COBALT TRANSPORTER; 1.
DR PANTHER; PTHR47891; TRANSPORTER-RELATED; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 254..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..48
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 314 AA; 36213 MW; 8ABD04859A73F04A CRC64;
MKQVFLSTTT EFKEIDALES GTWINLVNPS QSESIEIANA FGIDIADLRA PLDAEEMSRL
TIEDEYTLII VDVPITEERN TQTYYVTIPL GIIITEEAII TTCLEKLPLL DIFIHRRLRN
FYTFMKSRFI FQILYHNAEL YLTALRSIDR KSEQIESQLH KSTRNEELIE LMELEKTIVY
FKASLKTNER VIKKLTSSTS NIKKYLEDED LLEDTLIETQ QAIEMADIYG NILHSMTETF
ASIISNNQNN IMKALALVTI VMSIPTMIFS AYGMNFKNNE LPLNGEPHAF WIIMFIAFAM
SASLMAYLMH KKLF
//
