ID F2I838_AERUA Unreviewed; 513 AA.
AC F2I838;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Putative toxin-antitoxin system toxin component, PIN family {ECO:0000313|EMBL:AEA00693.1};
GN OrderedLocusNames=HMPREF9243_0558 {ECO:0000313|EMBL:AEA00693.1};
OS Aerococcus urinae (strain CCUG 59500 / ACS-120-V-Col10a).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Aerococcaceae; Aerococcus;
OC Aerococcus incertae sedis.
OX NCBI_TaxID=2976812 {ECO:0000313|EMBL:AEA00693.1, ECO:0000313|Proteomes:UP000008129};
RN [1] {ECO:0000313|Proteomes:UP000008129}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACS-120-V-Col10a {ECO:0000313|Proteomes:UP000008129};
RA Durkin A.S., Madupu R., Radune D., Hostetler J., Torralba M., Gillis M.,
RA Methe B., Sutton G., Nelson K.E.;
RT "Complete genome sequence of Aerococcus urinae strain ACS-120-V-Col10a.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363032};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363032}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. {ECO:0000256|RuleBase:RU363032}.
CC -!- SIMILARITY: In the C-terminal section; belongs to the OsmX family.
CC {ECO:0000256|ARBA:ARBA00035642}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the binding-protein-
CC dependent transport system permease family.
CC {ECO:0000256|ARBA:ARBA00035652}.
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DR EMBL; CP002512; AEA00693.1; -; Genomic_DNA.
DR RefSeq; WP_013668944.1; NC_015278.1.
DR AlphaFoldDB; F2I838; -.
DR STRING; 866775.HMPREF9243_0558; -.
DR KEGG; aur:HMPREF9243_0558; -.
DR PATRIC; fig|866775.3.peg.527; -.
DR eggNOG; COG1174; Bacteria.
DR eggNOG; COG1732; Bacteria.
DR HOGENOM; CLU_038355_0_1_9; -.
DR Proteomes; UP000008129; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR CDD; cd13610; PBP2_ChoS; 1.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; MetI-like; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR InterPro; IPR007210; ABC_Gly_betaine_transp_sub-bd.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR PANTHER; PTHR30177; GLYCINE BETAINE/L-PROLINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW; 1.
DR PANTHER; PTHR30177:SF4; OSMOPROTECTANT IMPORT PERMEASE PROTEIN OSMW; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR Pfam; PF04069; OpuAC; 1.
DR SUPFAM; SSF161098; MetI-like; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363032};
KW Reference proteome {ECO:0000313|Proteomes:UP000008129};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363032};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363032}; Transport {ECO:0000256|RuleBase:RU363032}.
FT TRANSMEM 24..47
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 68..95
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 146..172
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 179..202
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 208..227
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT DOMAIN 20..199
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50928"
SQ SEQUENCE 513 AA; 55441 MW; EEA46C71E15463C3 CRC64;
MIAELGSIFQ ERGSDLLAAS WEHLTLSLTA LLIALIIGIP LAIGLRSQPR IAEGALQLTG
VLQTIPSLAL LGLLIPLVGI GTVPALIALV VYALLPIFQN TYVGLTEIDD SIEEAAVAFG
MSAMRRLLKV EIPIALPVIV SGIRQALVLI IGTATLAALI GGGGLGTFIL LGIDRNQPLL
TLVGAIGSAL LALTFSALIK FLQNKSPLVV VTSLLGLFLV IGGVNLYQNA QAPDQKVVIA
GKLGSEPDIL INMYQELIQA EDDQFQVELK PNFGKTSFLF EALNHQEVDI YPEFSGTILG
SLLENPPANH PGELSKGETY DLAKQGLEEE YQLTLLEPMA YENTYAILMR RDQAEAMGIK
KISDLKPYAN NLSAGFTLEF IDREDGYQGI QSLYQLHFGQ VSSMEPALRY QAIAQGEVDL
VDGYSTDSEI KAYDLVALED DLGLFPHYQG APMLRLDYAQ DHPQVVAALN RLAGMITEEE
MIQMNYQVSQ EGQSAKEVAH QFLLDKGLIG GGQ
//
