ID   F2JKQ6_CELLD            Unreviewed;       700 AA.
AC   F2JKQ6;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Cell wall hydrolase/autolysin {ECO:0000313|EMBL:ADZ83309.1};
GN   OrderedLocusNames=Clole_1584 {ECO:0000313|EMBL:ADZ83309.1};
OS   Cellulosilyticum lentocellum (strain ATCC 49066 / DSM 5427 / NCIMB 11756 /
OS   RHM5) (Clostridium lentocellum).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Cellulosilyticaceae;
OC   Cellulosilyticum.
OX   NCBI_TaxID=642492 {ECO:0000313|EMBL:ADZ83309.1, ECO:0000313|Proteomes:UP000008467};
RN   [1] {ECO:0000313|EMBL:ADZ83309.1, ECO:0000313|Proteomes:UP000008467}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49066 / DSM 5427 / NCIMB 11756 / RHM5
RC   {ECO:0000313|Proteomes:UP000008467};
RX   PubMed=21398547; DOI=10.1128/JB.00239-11;
RG   US DOE Joint Genome Institute;
RA   Miller D.A., Suen G., Bruce D., Copeland A., Cheng J.F., Detter C.,
RA   Goodwin L.A., Han C.S., Hauser L.J., Land M.L., Lapidus A., Lucas S.,
RA   Meincke L., Pitluck S., Tapia R., Teshima H., Woyke T., Fox B.G.,
RA   Angert E.R., Currie C.R.;
RT   "Complete genome sequence of the cellulose-degrading bacterium
RT   Cellulosilyticum lentocellum.";
RL   J. Bacteriol. 193:2357-2358(2011).
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DR   EMBL; CP002582; ADZ83309.1; -; Genomic_DNA.
DR   RefSeq; WP_013656607.1; NC_015275.1.
DR   AlphaFoldDB; F2JKQ6; -.
DR   STRING; 642492.Clole_1584; -.
DR   KEGG; cle:Clole_1584; -.
DR   eggNOG; COG0860; Bacteria.
DR   HOGENOM; CLU_014322_10_0_9; -.
DR   Proteomes; UP000008467; Chromosome.
DR   GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:InterPro.
DR   GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
DR   CDD; cd02696; MurNAc-LAA; 1.
DR   Gene3D; 2.60.40.3500; -; 1.
DR   Gene3D; 3.30.457.10; Copper amine oxidase-like, N-terminal domain; 1.
DR   Gene3D; 3.40.630.40; Zn-dependent exopeptidases; 1.
DR   InterPro; IPR021731; AMIN_dom.
DR   InterPro; IPR012854; Cu_amine_oxidase-like_N.
DR   InterPro; IPR036582; Mao_N_sf.
DR   InterPro; IPR002508; MurNAc-LAA_cat.
DR   PANTHER; PTHR30404; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; 1.
DR   PANTHER; PTHR30404:SF0; N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIC; 1.
DR   Pfam; PF01520; Amidase_3; 1.
DR   Pfam; PF11741; AMIN; 1.
DR   Pfam; PF07833; Cu_amine_oxidN1; 1.
DR   SMART; SM00646; Ami_3; 1.
DR   SUPFAM; SSF55383; Copper amine oxidase, domain N; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ADZ83309.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008467};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..700
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003279017"
FT   DOMAIN          582..694
FT                   /note="MurNAc-LAA"
FT                   /evidence="ECO:0000259|SMART:SM00646"
FT   REGION          148..184
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        160..180
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   700 AA;  77474 MW;  90B725B7107A14B3 CRC64;
     MSKKLGIMLL AATLFCTNAV PTTAATIVYD GRAHEYNLPA ISLYVNGNKI ATTMDPIQLE
     GRVLVPAREV FTPMGAKVSW DAKAKQVTVA YKDTTMLLTV NQKEVWLNGK TVSLDVPAKI
     INDKVMIPVR FISEQLGFIV DWNGSNRQVS ITEPTSPPTE EEKPPVEEEP PVEEEKPSIS
     NEEYIGTSNK HQIELPSASY SQTKVMEVSV NENNGQHTTF ISAASPISNA KIELQAGKVI
     IDIGNSKSQL SNTISPTNNT YIKNIRTSQF TTDTTRVVLD LKSGALVKAG FSEDRSSIMV
     QLSNQKIEQI KYMQKNGADT LYYKGLSKDQ IILDYNEKEN LLNFTVPHTT IETTINWTQL
     NGRYIDKVTI NGEDNQVKGS IWLKGKVDYQ LTSDYQGATL TLSAYTEVPP VEEVTDSLVY
     VSGDNPTIQL FNIPGLNKNA IKVTDDYRNK TLVFDLGKDY SSVLKNNNMV INDTRINKIQ
     VATNGTTKIT VVTQKVYAYN FYESDGKISL QMVRPKEKYN QIVVLDAGHG GSDSGAVGNG
     LTEKGINYKQ AMALYKLLEA DSQIKVYMTR ETDVYPTLQF RTALANDIEA DLFVSIHNNS
     ASASIRGAET LYFPSTTDTR GKQVAQIVQN ALVNKCGMIN RGIKARSDLY VLRTSNMPAI
     LIETGFISNS AEAALLNSTA FTNKWAQAIY ESIVESFRFL
//