ID F2JUB0_MARM1 Unreviewed; 517 AA.
AC F2JUB0;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:ADZ92729.1};
GN OrderedLocusNames=Marme_3515 {ECO:0000313|EMBL:ADZ92729.1};
OS Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 /
OS MMB-1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Marinomonas.
OX NCBI_TaxID=717774 {ECO:0000313|EMBL:ADZ92729.1, ECO:0000313|Proteomes:UP000001062};
RN [1] {ECO:0000313|EMBL:ADZ92729.1, ECO:0000313|Proteomes:UP000001062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1
RC {ECO:0000313|Proteomes:UP000001062};
RX PubMed=22675599; DOI=10.4056/sigs.2545743;
RA Lucas-Elio P., Goodwin L., Woyke T., Pitluck S., Nolan M., Kyrpides N.C.,
RA Detter J.C., Copeland A., Teshima H., Bruce D., Detter C., Tapia R.,
RA Han S., Land M.L., Ivanova N., Mikhailova N., Johnston A.W.,
RA Sanchez-Amat A.;
RT "Complete genome sequence of the melanogenic marine bacterium Marinomonas
RT mediterranea type strain (MMB-1(T)).";
RL Stand. Genomic Sci. 6:63-73(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP002583; ADZ92729.1; -; Genomic_DNA.
DR RefSeq; WP_013662631.1; NZ_CP047696.1.
DR AlphaFoldDB; F2JUB0; -.
DR STRING; 717774.Marme_3515; -.
DR KEGG; mme:Marme_3515; -.
DR PATRIC; fig|717774.3.peg.3619; -.
DR eggNOG; COG0845; Bacteria.
DR eggNOG; COG5569; Bacteria.
DR HOGENOM; CLU_018816_13_1_6; -.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000001062; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 2.40.50.320; Copper binding periplasmic protein CusF; 1.
DR InterPro; IPR021647; CusF_Ec.
DR InterPro; IPR042230; CusF_sf.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR045800; HMBD.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30097; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR PANTHER; PTHR30097:SF15; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR Pfam; PF11604; CusF_Ec; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR Pfam; PF19335; HMBD; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001062}.
FT DOMAIN 50..75
FT /note="Heavy metal binding"
FT /evidence="ECO:0000259|Pfam:PF19335"
FT DOMAIN 113..321
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 517 AA; 57686 MW; 7DB4B2C906D9D05B CRC64;
MKVIGYIGVF VLGGVLSITG YHFSFQAFNV MNGEMNTGAV VTEDEKTPLY WVAPMDPNYR
RDKPGQSPMG MDLIPFYGDD QGSNNQGAGT VSISPEVVNN LGVRTGKVFE DMLKPDIRTV
GYLAYNEDNI IHIHPRVEGW IEKSFIKSNG DSVEKGQPLF DLYSPTLVNA QEEFVFALAR
KDQRMINAGE ERLKALQVSN RFIQALKKTR KVSQTVRFFA PQSGVIDNLG IQDGFYIKPG
TTLMSIADLS EVWLDAEVFE RQAHLVAVGQ PIEAVMDFLP GKTFVSNVDF IYPTLNAKNR
TLRVRIRLDN PEQLLKPDMF AHVRIETTQS GKKRLIPKEA LIRGGEQNRV VLALGEGRYK
SIAVETGAFG DDYVEILDGL VLGDEVVTSA QFLLDSESSK SSDFKRMNID SEKASMPDSS
TEMTETSMSS NEMSAAEPAN NVWVAARINS IDATARKMNV DHDPIADWNW PKMTMDFALA
DWLEVEELPV GKDIQLEITR ESSVKFIVSD YFDADTE
//
