ID F2KC25_PSEBN Unreviewed; 429 AA.
AC F2KC25;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Probable M18 family aminopeptidase 2 {ECO:0000256|HAMAP-Rule:MF_00467};
DE EC=3.4.11.- {ECO:0000256|HAMAP-Rule:MF_00467};
GN Name=apeB {ECO:0000256|HAMAP-Rule:MF_00467};
GN ORFNames=PSEBR_a4195 {ECO:0000313|EMBL:AEA70602.1};
OS Pseudomonas brassicacearum (strain NFM421).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=994484 {ECO:0000313|EMBL:AEA70602.1, ECO:0000313|Proteomes:UP000006692};
RN [1] {ECO:0000313|EMBL:AEA70602.1, ECO:0000313|Proteomes:UP000006692}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NFM421 {ECO:0000313|EMBL:AEA70602.1,
RC ECO:0000313|Proteomes:UP000006692};
RX PubMed=21515771; DOI=10.1128/JB.00411-11;
RA Ortet P., Barakat M., Lalaouna D., Fochesato S., Barbe V., Vacherie B.,
RA Santaella C., Heulin T., Achouak W.;
RT "Complete genome sequence of a beneficial plant root-associated bacterium,
RT Pseudomonas brassicacearum.";
RL J. Bacteriol. 193:3146-3146(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NFM421;
RA Ortet P., Barakat M., Lalaouna D., Fochesato S., Barbe V., Santaella C.,
RA Heulin T., Achouak W.;
RT "Complete Genome Sequence of a beneficial plant roots-associated bacterium
RT Pseudomonas brassicacearum.";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|HAMAP-Rule:MF_00467, ECO:0000256|RuleBase:RU004387};
CC -!- SIMILARITY: Belongs to the peptidase M18 family.
CC {ECO:0000256|ARBA:ARBA00008290, ECO:0000256|HAMAP-Rule:MF_00467,
CC ECO:0000256|RuleBase:RU004386}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002585; AEA70602.1; -; Genomic_DNA.
DR RefSeq; WP_003204544.1; NC_015379.1.
DR AlphaFoldDB; F2KC25; -.
DR STRING; 994484.PSEBR_a4195; -.
DR GeneID; 57261052; -.
DR KEGG; pba:PSEBR_a4195; -.
DR HOGENOM; CLU_019532_2_0_6; -.
DR Proteomes; UP000006692; Chromosome.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-UniRule.
DR CDD; cd05658; M18_DAP; 1.
DR Gene3D; 2.30.250.10; Aminopeptidase i, Domain 2; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR HAMAP; MF_00467; Aminopeptidase_M18_2; 1.
DR InterPro; IPR022984; M18_aminopeptidase_2.
DR InterPro; IPR001948; Peptidase_M18.
DR InterPro; IPR023358; Peptidase_M18_dom2.
DR PANTHER; PTHR28570; ASPARTYL AMINOPEPTIDASE; 1.
DR PANTHER; PTHR28570:SF3; ASPARTYL AMINOPEPTIDASE; 1.
DR Pfam; PF02127; Peptidase_M18; 1.
DR PRINTS; PR00932; AMINO1PTASE.
DR SUPFAM; SSF101821; Aminopeptidase/glucanase lid domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000256|ARBA:ARBA00022438, ECO:0000256|HAMAP-
KW Rule:MF_00467};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_00467};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|HAMAP-
KW Rule:MF_00467};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049, ECO:0000256|HAMAP-
KW Rule:MF_00467};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|HAMAP-Rule:MF_00467};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|HAMAP-Rule:MF_00467}.
FT BINDING 82
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00467"
FT BINDING 156
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00467"
FT BINDING 401
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00467"
SQ SEQUENCE 429 AA; 47046 MW; C45D88B2C27CDEE0 CRC64;
MRAELNQGLI DFLKASPTPF HATASLAKRL EAAGYQRLDE RETWATEANG RYYVTRNDSS
IIAFKLGRNS PLHDGIRLVG AHTDSPCLRV KPQPELQRHG FWQLGVEVYG GALLAPWFDR
DLSLAGRVTF RRDGKVESQL IDFKAPIATI PNLAIHLNRE ANQGWAINPQ NELPPILAQF
AGDERVDFRA VLTDQLAREH GLNADVVLDY ELSFYDTQSA AVIGLHGDFI AGARLDNLLS
CYAGLQALLN TDTEETCVLV CNDHEEVGSC SACGADGPML EQTLRRLLPE GEEFVRTIQK
SLLVSADNAH GVHPNYADKH DANHGPKLNA GPVIKVNSNQ RYATNSETAG FFRHLCMAEE
VPVQSFVVRS DMGCGSTIGP ITASQLGVRT VDIGLPTFAM HSIRELCGSH DLAHLVKVLS
AFYASRELP
//
