ID F2LBM0_BURGS Unreviewed; 830 AA.
AC F2LBM0;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=DNA internalization-related competence protein ComEC/Rec {ECO:0000313|EMBL:AEA61395.1};
GN OrderedLocusNames=bgla_1g27800 {ECO:0000313|EMBL:AEA61395.1};
OS Burkholderia gladioli (strain BSR3).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=999541 {ECO:0000313|EMBL:AEA61395.1, ECO:0000313|Proteomes:UP000008316};
RN [1] {ECO:0000313|EMBL:AEA61395.1, ECO:0000313|Proteomes:UP000008316}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BSR3 {ECO:0000313|EMBL:AEA61395.1,
RC ECO:0000313|Proteomes:UP000008316};
RX PubMed=21478339; DOI=10.1128/JB.00420-11;
RA Seo Y.S., Lim J., Choi B.S., Kim H., Goo E., Lee B., Lim J.S., Choi I.Y.,
RA Moon J.S., Kim J., Hwang I.;
RT "Complete genome sequence of Burkholderia gladioli BSR3.";
RL J. Bacteriol. 193:3149-3149(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002599; AEA61395.1; -; Genomic_DNA.
DR RefSeq; WP_013698721.1; NC_015381.1.
DR AlphaFoldDB; F2LBM0; -.
DR STRING; 999541.bgla_1g27800; -.
DR KEGG; bgd:bgla_1g27800; -.
DR eggNOG; COG0658; Bacteria.
DR eggNOG; COG2333; Bacteria.
DR HOGENOM; CLU_010363_3_0_4; -.
DR Proteomes; UP000008316; Chromosome 1.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 461..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 493..513
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 519..535
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 574..770
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 830 AA; 88419 MW; 3AC0BBEA58D4A9D8 CRC64;
MREIWIAFAL GVVMLQRQAR LPGVAEAGAA LGVVALLLAL IVMVRRAAPS RGARWATILI
VLLLAALAGH GYAAIRAHLR LADDLPLEWR RREVLVTGVV RGLPARDAQG QRFLLDVDGQ
DTGLLRFPAR LRLSWIRYDR RDAAPPEVRP GERWRLRVRL KRPHANANAG LRDAEAAWLA
AGIRALGYVS SSRDASRLDE SPRDAAAVVD RLRHRVRERI RAVLDGAPHA GIVIALAIGA
QDDIAEVDRQ VLRATGTSHL VAISGLHIGM VGALAAWLAA AFWRRGSVRG MALPLWLPAP
HAGAWAAIAG AGCYAALAGF NVPAQRAWWM LAVACLAYLS GRSIAPSTTL AAALGCVLLA
DPWAVLMPGF WLSFGAVAVI LFAVSGRAAR PWPADEPAVV EAGGLDPGGT RQRLRRAAAR
LVRIGANGAR VQYAVTLGLA PFTVVWFGQV PLAGALANAF AIPWVGSLVT PIVLAGMALP
APLDVLVLRA AHALLTAMFA LFEAMPAGLA AVAEMPSPSW FALLAALAGT GWALMPRGWP
LRFAAPLAWL PLVLPPSQAP PAGALRLTLL DVGQGLAVLA ETAHHRLLFD AGPGAESTRA
GERIVVPFLR AKGIRSLDTL MISHADADHA GGAAAVLEAL PVRQLTGGLP RDNALWGLAR
AAGVADRLAC RAGQRWTWDG VHFAVLWPRA EPDADAPNAS SCVLHVSAGG QAALLTGDID
TGVERTLVRD ERAALAAEVL VVPHHGSRTS SWEPFVDAVA PRAAWFPLGH ANRFGHPHPT
VWARYAARGI ELARSDRDGA VSMMLNDPSE PSGLLVQRYR ERHRRYWMAP
//
