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Database: UniProt
Entry: F2N6T4_CORGP
LinkDB: F2N6T4_CORGP
Original site: F2N6T4_CORGP 
ID   F2N6T4_CORGP            Unreviewed;       591 AA.
AC   F2N6T4;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   25-OCT-2017, entry version 49.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577};
GN   OrderedLocusNames=Corgl_0002 {ECO:0000313|EMBL:AEB06133.1};
OS   Coriobacterium glomerans (strain ATCC 49209 / DSM 20642 / JCM 10262 /
OS   PW2).
OC   Bacteria; Actinobacteria; Coriobacteriia; Coriobacteriales;
OC   Coriobacteriaceae; Coriobacterium.
OX   NCBI_TaxID=700015 {ECO:0000313|EMBL:AEB06133.1, ECO:0000313|Proteomes:UP000006851};
RN   [1] {ECO:0000313|Proteomes:UP000006851}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 49209 / DSM 20642 / JCM 10262 / PW2
RC   {ECO:0000313|Proteomes:UP000006851};
RX   PubMed=23961308; DOI=10.4056/sigs.3507020;
RA   Stackebrandt E., Zeytun A., Lapidus A., Nolan M., Lucas S., Hammon N.,
RA   Deshpande S., Cheng J.F., Tapia R., Goodwin L.A., Pitluck S.,
RA   Liolios K., Pagani I., Ivanova N., Mavromatis K., Mikhailova N.,
RA   Huntemann M., Pati A., Chen A., Palaniappan K., Chang Y.J., Land M.,
RA   Hauser L., Rohde M., Pukall R., Goker M., Detter J.C., Woyke T.,
RA   Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C.,
RA   Klenk H.P.;
RT   "Complete genome sequence of Coriobacterium glomerans type strain
RT   (PW2(T)) from the midgut of Pyrrhocoris apterus L. (red soldier
RT   bug).";
RL   Stand. Genomic Sci. 8:15-25(2013).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|RuleBase:RU000577,
CC       ECO:0000256|SAAS:SAAS00747914}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP002628; AEB06133.1; -; Genomic_DNA.
DR   RefSeq; WP_013707876.1; NC_015389.1.
DR   STRING; 700015.Corgl_0002; -.
DR   EnsemblBacteria; AEB06133; AEB06133; Corgl_0002.
DR   KEGG; cgo:Corgl_0002; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   KO; K02313; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000006851; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006851};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006851}.
FT   DOMAIN      257    385       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      497    566       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   591 AA;  64883 MW;  3E112F05837F7750 CRC64;
     MDNEADIILE DTISFCERDE RDARLISMLR QSRADSLTGD KLTIEAPSRF AYSYLMKQRK
     IIERYLEEIA FCPLTLHIGI PRSSSGDADG RSAAPAAASA VPAGAAGDGG RSLEATSGET
     SAAALAADAH GPTAERENAA ADGDPRARET PSGAAAAVLG TQQRDAAETK GVTIKNTLSQ
     DAFRKMMNSI AGQESRQPKP KTMAEGASGR EGADGGDFPS VPVNSKFTFE NFVYGEENKQ
     AYQSSLRFAA FAEEPGSYTS LFIYGNSGLG KTHLLLAIEN YLAETKPYMR VKYANSQAYI
     DDFINEVAIQ KTDGHAILRD YHAADILIID DIQNIIGKTA SIDYFFRLMD EFIRDNKKVV
     IASDRAPKKL GMDERLTSRF NGGMLCLVSE PGFEMKYAIL KRYYENNVLA SDAAPLTRET
     TDVSLLSSIY TGGGHLSDAQ LRHMAEISGT NIRELESFCE RCACDSYEKE QVGEELTGED
     IEAIADEYFD TARKKIHIDT VQSVVEEFYH VTHEEMIGPR RTANIAFARH VAVYLSNDMC
     DTTTPAVGAQ FGGRDHSTVL NSMKVIEKKM KGDRALCEEL QQLRNKIVLK S
//
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