ID F2NZ18_9VIRU Unreviewed; 873 AA.
AC F2NZ18;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
OS Diadromus pulchellus ascovirus 4a.
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC Pimascovirales; Ascoviridae; Toursvirus; Toursvirus dptv1a.
OX NCBI_TaxID=158683 {ECO:0000313|EMBL:CCA61446.1, ECO:0000313|Proteomes:UP000203898};
RN [1] {ECO:0000313|EMBL:CCA61446.1, ECO:0000313|Proteomes:UP000203898}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=19636425; DOI=10.1371/journal.pone.0006397;
RA Bigot Y., Renault S., Nicolas J., Moundras C., Demattei M.V., Samain S.,
RA Bideshi D.K., Federici B.A.;
RT "Symbiotic virus at the evolutionary intersection of three types of large
RT DNA viruses; iridoviruses, ascoviruses, and ichnoviruses.";
RL PLoS ONE 4:e6397-e6397(2009).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550,
CC ECO:0000256|RuleBase:RU004279};
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000256|ARBA:ARBA00006460, ECO:0000256|RuleBase:RU004279}.
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DR EMBL; CU469068; CCA61446.1; -; Genomic_DNA.
DR RefSeq; YP_009220717.1; NC_011335.1.
DR Proteomes; UP000203898; Genome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 4.10.860.120; RNA polymerase II, clamp domain; 1.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR000722; RNA_pol_asu.
DR InterPro; IPR006592; RNA_pol_N.
DR InterPro; IPR007080; RNA_pol_Rpb1_1.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR044893; RNA_pol_Rpb1_clamp_domain.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF37; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1; 1.
DR Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR Pfam; PF00623; RNA_pol_Rpb1_2; 2.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR SMART; SM00663; RPOLA_N; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU004279};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|RuleBase:RU004279};
KW Reference proteome {ECO:0000313|Proteomes:UP000203898};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004279};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004279}.
FT DOMAIN 188..526
FT /note="RNA polymerase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00663"
SQ SEQUENCE 873 AA; 98716 MW; 1E51F0B8C963649A CRC64;
MSYVRELKSI SFAVSSPEDI RNKSVYEVKS IKLGDSKYNT IYDPRGGALF GKACETCKQH
EQACTGHFGH IELNAPVVHP LFFNHVFNIL KVVCSSCSRL LVSRQHLEFS GILKYDGERR
LAEIINKVKK FKECFHCGVL KREYTIKKDP LLNIIQCDGV DVSDIEIKAV FDDIDAETLD
MLNISHPRNC CLEVFPVIPP CCRPYEIVCN TLKEDDLSRQ LVEIVKANLQ LKDNETNEAL
IHNLKLKIET YCRSPKKKGK LVTCNGEQPV GIRERLTGKT GQMRDNLMGK RTEMSSRTVI
GPDPTLRVDE VGVPEEIVNN TTFPEIVYPH NIEYLKQLVK TEKIEKIKRN DKIIRIDLQI
YEDVASFLEI GDVVVRRDGG RFTTSSAKFD LEPTDRILRC GVDVTPENVP VPKEPDVRVG
DSVLRKIRNG DWVLMNRQPT LWKGSMMAFK CRIHKSRTFT FNLAVCKAFN ADFDGDEQNG
HFPQSIEAVV ELMSLSTPKH CLLSSTNGTP VIVVLQDALL GAYLITDDDG FVIDRDDYND
LIMHLTKGYD GVMRRRRQIR ATLKSRGLPC AERDLRRGKN IVSLLFEESF NFKHDDFEID
RGVVVSGRLS KAYLGSSHNS IMSMLVSQYS PDVCMDFLND IQFMTNKWML SRSFSINLSD
FRSVDGVRGV VDDKLAEAKV VEETIINKKL KEAKINGVLP NAKDLGMKIS TQIENNNMVT
TILSGSKGDY FNLGQVKGLL GQQIINSKRI PTKIDNGTRS LPHYPRNELS DRDRYESRGF
IMNGFYDGLN VKEFFFHAMS GRQGVCDTAM TTFMSGYNMR KLVKLTEDIK IQNDRVVADS
SGCVYDFSYG PLGFNPENGV PDVDAVINKI VNS
//
