ID F2Q0Q0_TRIEC Unreviewed; 632 AA.
AC F2Q0Q0;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Import receptor {ECO:0000313|EMBL:EGE07718.1};
GN ORFNames=TEQG_06701 {ECO:0000313|EMBL:EGE07718.1};
OS Trichophyton equinum (strain ATCC MYA-4606 / CBS 127.97) (Horse ringworm
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=559882 {ECO:0000313|Proteomes:UP000009169};
RN [1] {ECO:0000313|Proteomes:UP000009169}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4606 / CBS 127.97 {ECO:0000313|Proteomes:UP000009169};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion
CC outer membrane {ECO:0000256|ARBA:ARBA00004572}; Single-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004572}.
CC -!- SIMILARITY: Belongs to the Tom70 family.
CC {ECO:0000256|ARBA:ARBA00038030}.
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DR EMBL; DS995764; EGE07718.1; -; Genomic_DNA.
DR AlphaFoldDB; F2Q0Q0; -.
DR VEuPathDB; FungiDB:TEQG_06701; -.
DR eggNOG; KOG0547; Eukaryota.
DR HOGENOM; CLU_017516_0_1_1; -.
DR Proteomes; UP000009169; Unassembled WGS sequence.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015450; F:protein-transporting ATPase activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR005687; Tom70.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR NCBIfam; TIGR00990; 3a0801s09; 1.
DR PANTHER; PTHR46208; MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70; 1.
DR PANTHER; PTHR46208:SF1; MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70; 1.
DR Pfam; PF13432; TPR_16; 3.
DR Pfam; PF14559; TPR_19; 1.
DR SMART; SM00028; TPR; 10.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 4.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787};
KW Receptor {ECO:0000313|EMBL:EGE07718.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 44..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 377..410
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 411..444
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 479..512
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 554..587
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 68..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..116
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 632 AA; 69561 MW; EB70F4ED0047212E CRC64;
MAPIEPVVPS LPSSTIQQHI ENTAALPSPS VWDRISSWAS ENKALVYTIA GVAVVVTSAG
VVYYLSDTGR PTQVSGQSGE KRKSKKERRK EKKAEQEKKA ATSEKSETKA ATEQAPEELP
DVDESNVDSL PAQTRERYAG ILKAAGNKAF GSKDYNRAIE LYGKAILCKP DPVYYSNRAA
CYNALGEWEK VVEDTTAALA MDDEYIKAMN RRANAYDKLG KYSEALLDYT ASCILDGFAS
DTGKAAVERL LKQVAEEKGR AILEGKGKKL PSATFVSNYL QSFRPKPVPE ELNESVELKE
DSGLGQLRKG LLAVSKSTGD GYDEAARAFE KALELGELGK LEALALNMRA TFTYLAGEAA
AALTDLNKSI ELDPSLVQSY IKRASLYLEM GNRESAQDDF DLAVTQNKDD PDIYYHRAQL
HFILGELGEA AKDYQKSIDL DRDFIYSHIQ LGVTQYKLGS VASAMATFKR TLKNFENVAE
VYNYYGELLL DMQKFSEAIE KFDRAVELEK SNKPWSINVL PLINKALAIF QWKQDFQEAE
NLCQKALIID PDCDIAIATL AQLLLQQGKV SQALKYFERA AELARTEAEV INAVSYAEAT
RAQLEVQEKY PKLAARLAQM GGAAGLGAPG GF
//
