ID F2R196_STRVP Unreviewed; 317 AA.
AC F2R196;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Probable hydrogen peroxide-inducible genes activator {ECO:0000256|ARBA:ARBA00040885};
GN OrderedLocusNames=SVEN_4701 {ECO:0000313|EMBL:CCA57987.1};
OS Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM
OS 4526 / NBRC 13096 / PD 04745).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=953739 {ECO:0000313|EMBL:CCA57987.1, ECO:0000313|Proteomes:UP000006854};
RN [1] {ECO:0000313|EMBL:CCA57987.1, ECO:0000313|Proteomes:UP000006854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10712 {ECO:0000313|EMBL:CCA57987.1};
RX PubMed=21463507; DOI=10.1186/1471-2164-12-175;
RA Pullan S.T., Bibb M.J., Merrick M.;
RT "Genome-wide analysis of the role of GlnR in Streptomyces venezuelae
RT provides new insights into global nitrogen regulation in actinomycetes.";
RL BMC Genomics 12:175-175(2011).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; FR845719; CCA57987.1; -; Genomic_DNA.
DR AlphaFoldDB; F2R196; -.
DR STRING; 953739.SVEN_4701; -.
DR KEGG; sve:SVEN_4701; -.
DR PATRIC; fig|953739.5.peg.7205; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_4_11; -.
DR OrthoDB; 9775392at2; -.
DR Proteomes; UP000006854; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08411; PBP2_OxyR; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30346:SF26; HYDROGEN PEROXIDE-INDUCIBLE GENES ACTIVATOR; 1.
DR PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006854}.
FT DOMAIN 10..67
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 317 AA; 33767 MW; E4A70AA4F93F93CF CRC64;
MIPARRVKQP SLSQLRAFAA VAEQLHFRDA AAAIGMSQPA LSGAVSALEE ALGVQLLERT
TRKVLLSPAG ERLAVRARAV LDAVSELMEE AEAARAPFTG VLRLGVIPTV APYLLPTVLR
LVHRRYPDLD LQVHEEQTSS LLEGLAAGRL DLLLLAVPLG VPGVTELPLF DEDFVLVTPQ
GHPLAGRDDI PRDALKELRL LLLDEGHCLR DQALDICREA GRTDGAEVTT TAAGLATLVQ
LVAGGLGVTL LPRTAVTVET ARNNALWTGL FAEPAPARRI ALAMRTGAAR QAEFEELAEA
LRGAMRGLPV RVLDGGS
//
