ID F2R4U7_STRVP Unreviewed; 455 AA.
AC F2R4U7;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Fe-S protein lactate dehydrogenase {ECO:0000313|EMBL:CCA55968.1};
GN OrderedLocusNames=SVEN_2682 {ECO:0000313|EMBL:CCA55968.1};
OS Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM
OS 4526 / NBRC 13096 / PD 04745).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=953739 {ECO:0000313|EMBL:CCA55968.1, ECO:0000313|Proteomes:UP000006854};
RN [1] {ECO:0000313|EMBL:CCA55968.1, ECO:0000313|Proteomes:UP000006854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 /
RC PD 04745 {ECO:0000313|Proteomes:UP000006854};
RX PubMed=21463507; DOI=10.1186/1471-2164-12-175;
RA Pullan S.T., Bibb M.J., Merrick M.;
RT "Genome-wide analysis of the role of GlnR in Streptomyces venezuelae
RT provides new insights into global nitrogen regulation in actinomycetes.";
RL BMC Genomics 12:175-175(2011).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; FR845719; CCA55968.1; -; Genomic_DNA.
DR RefSeq; WP_015033886.1; NZ_JABVZO010000616.1.
DR AlphaFoldDB; F2R4U7; -.
DR STRING; 953739.SVEN_2682; -.
DR GeneID; 69864816; -.
DR KEGG; sve:SVEN_2682; -.
DR PATRIC; fig|953739.5.peg.4872; -.
DR eggNOG; COG0277; Bacteria.
DR HOGENOM; CLU_017779_9_1_11; -.
DR OrthoDB; 9811557at2; -.
DR Proteomes; UP000006854; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.30.70.2740; -; 1.
DR InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR InterPro; IPR006094; Oxid_FAD_bind_N.
DR InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR PANTHER; PTHR42934; GLYCOLATE OXIDASE SUBUNIT GLCD; 1.
DR PANTHER; PTHR42934:SF2; GLYCOLATE OXIDASE SUBUNIT GLCD; 1.
DR Pfam; PF02913; FAD-oxidase_C; 1.
DR Pfam; PF01565; FAD_binding_4; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006854}.
FT DOMAIN 36..215
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
SQ SEQUENCE 455 AA; 47699 MW; 2A400407D2571504 CRC64;
MDDLLTRLRA GLPAEALLTD PDVTASYAND MASFCESGAP AVVVLPRTVE QVRHVMRTAT
ELRVPVVPQG ARTGLSGGAN ASEGCIVLSL VKMDRILEIN PVDRIAVVEP GVINAVLSRA
VAEHGLYYPP DPSSWEMCTI GGNIGTASGG LCCVKYGVTA EYVLGLDVVL ADGRLLTTGR
RTAKGVAGYD LTRLFVGSEG SLGIVVRAVL ALRPQPPAQL ALAAEFPSSA AACEAVCAIM
ERGHTPSLLE LMDRTTVQAV NKLARMGLPD TTEALLLCAF DTPDPAADLA AVGELCKAAG
ATEVVPAADT AESELLLQAR RLSLTALETI KSATMIDDVC VPRTRLAEML DGTAAVARKY
GLTIGVCAHA GDGNTHPVVC FDHTDEDESR RARESFDEIM ALGLALGGTI TGEHGVGVLK
KDWLARELGP VGLELQRGIK ATFDPLGLLN PGKLF
//
