ID F2RHA7_STRVP Unreviewed; 481 AA.
AC F2RHA7;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Xanthine or uracil or thiamine or ascorbate permease family protein {ECO:0000313|EMBL:CCA57435.1};
GN OrderedLocusNames=SVEN_4149 {ECO:0000313|EMBL:CCA57435.1};
OS Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM
OS 4526 / NBRC 13096 / PD 04745).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=953739 {ECO:0000313|EMBL:CCA57435.1, ECO:0000313|Proteomes:UP000006854};
RN [1] {ECO:0000313|EMBL:CCA57435.1, ECO:0000313|Proteomes:UP000006854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10712 {ECO:0000313|EMBL:CCA57435.1};
RX PubMed=21463507; DOI=10.1186/1471-2164-12-175;
RA Pullan S.T., Bibb M.J., Merrick M.;
RT "Genome-wide analysis of the role of GlnR in Streptomyces venezuelae
RT provides new insights into global nitrogen regulation in actinomycetes.";
RL BMC Genomics 12:175-175(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
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DR EMBL; FR845719; CCA57435.1; -; Genomic_DNA.
DR RefSeq; WP_015035346.1; NZ_JABVZO010000370.1.
DR AlphaFoldDB; F2RHA7; -.
DR STRING; 953739.SVEN_4149; -.
DR GeneID; 69866242; -.
DR KEGG; sve:SVEN_4149; -.
DR PATRIC; fig|953739.5.peg.6649; -.
DR eggNOG; COG2252; Bacteria.
DR HOGENOM; CLU_024508_0_0_11; -.
DR OrthoDB; 9808458at2; -.
DR Proteomes; UP000006854; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006854};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 41..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 419..448
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 460..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 481 AA; 49543 MW; AE333A0FC524BEAC CRC64;
MSTTATAKAT SPESPDPSTS GLDRYFKISQ RGSTVAREVR GGFATFFAMA YIIVLNPIIL
GSAKDMYGHQ LDSGQLVTAT VLTAAFSTLL MGVIGNVPIA LAAGLGVNTV VALQLAPKMS
WPDAMGMVVL AGVVVMLLVA TGLRERVMNA VPVGLRKGIA IGIGLFIMLI GLVDSGFVSR
IPDAAHTTVP LQLGGDGHLT GWPVLVFILG TLLTLALIIR KVPGAILISI VVMTIVAMVI
NAVATVPSWG LTTPKWPGNP VASPDFGLVG EVSLFGGFEK VGVLTGVLFV FTVLLSCFFD
AMGTILGVGD EAKLMDKDGN FPGINKVLLV DGLAVASGGA TSSSATTCFV ESTAGVGEGA
RTGLASVVTG GLFSVALFLT PLATMVPSQA ATPALLAVGF LILAGSVKDI DWSDFTIAVP
AFLAMVMMPF TYSITNGIGI GFIAFSVLRL AAGRGREVPV AMYVVSAVFV FYYAMPALGL
T
//
