ID   F2RTU7_TRIT1            Unreviewed;       823 AA.
AC   F2RTU7;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=CorA family metal ion transporter {ECO:0000313|EMBL:EGD94746.1};
GN   ORFNames=TESG_02251 {ECO:0000313|EMBL:EGD94746.1};
OS   Trichophyton tonsurans (strain CBS 112818) (Scalp ringworm fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=647933;
RN   [1] {ECO:0000313|EMBL:EGD94746.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 112818 {ECO:0000313|EMBL:EGD94746.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Henn M., Martinez D., Young S.K., Zeng Q., Gargeya S., Haas B.,
RA   Alvarado L., Berlin A., Chapman S., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Howarth C.,
RA   Larson L., Mehta T., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., White J., Yandava C., White T.C.,
RA   Abdel-Rahman S., Graser Y., Gurr S.J., Kohler G., Martinez-Rossi N.,
RA   Oliver B.C., Rossi A., Shelest E., Summerbell R., Lander E., Nusbaum C.,
RA   Birren B.;
RT   "Annotation of Trichophyton tonsurans strain CBS 112818.";
RL   Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC       family. {ECO:0000256|ARBA:ARBA00009765}.
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DR   EMBL; GG698484; EGD94746.1; -; Genomic_DNA.
DR   AlphaFoldDB; F2RTU7; -.
DR   HOGENOM; CLU_007127_10_0_1; -.
DR   OrthoDB; 1358357at2759; -.
DR   Proteomes; UP000009172; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd12829; Alr1p-like; 1.
DR   Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR   Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR   InterPro; IPR044089; Alr1-like.
DR   InterPro; IPR045861; CorA_cytoplasmic_dom.
DR   InterPro; IPR045863; CorA_TM1_TM2.
DR   InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR   PANTHER; PTHR21535; MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8; 1.
DR   PANTHER; PTHR21535:SF51; MANGANESE RESISTANCE PROTEIN MNR2; 1.
DR   Pfam; PF01544; CorA; 1.
DR   SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR   SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        795..816
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..86
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          263..282
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          307..327
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          416..495
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          642..662
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        14..30
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        37..51
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        52..66
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        268..282
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        440..483
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   823 AA;  93203 MW;  1714550C2AC8AA1B CRC64;
     MDPTNSAMGA ERSAPKKRRH RASRKKRNRR PSFAPAGDNS HFQSPLSRVD TQPNEENEDT
     KDASLTETRP RPFYNLGRSG GGNLSETSLE SEALLDHRNQ PMMRPRRESR LAQSFRPDQL
     LVESPSSSRT KIRRHEILPE DEFAITDDRS PLLNSSAQNG GALRGYGSDL ISTFSMPPGM
     GSPTSRRSPQ NSYTPDTFLA SRQGYDVNNP PSMPGSPKIM PNNMGYDETV ITGPEFVRQQ
     SPEALSCHSL PMDAVVNVDA DSRRPGLQSR HGSMSRSPAD LQRRRTLTLP VEEDVCFPAS
     GLSDLGEEDL QSHIPTGGDT RERRRRSRRV WPDLSVLDEW SQHEKEARSG GTRSKRIDEP
     VLIGGRLRTR NLVWKQDEEE EAPYRFTYFN EDFQSTLHSQ TLSELEQPGQ TFRDLFIPEP
     PLLEDDSSDE EDDSSPYSGT TSRDKHPSIS TNANHHTNNL PDLLSDNPDS TSPQPTNGNS
     RVPSPKKEPR YGPRPTFWLD VLSPTDSEMR IIAKAFGIHA LTAEDIMMQE AREKVELFRN
     YYFINYRTFE QDVNSPDFLE PVNMYVVVFR EGLLSFHFSR TPHPANVRRR IRQLKDYLIL
     SADWISYAII DDITDVFGPL IHAIEEEVDE IDDKILRLHS DDKEMGSDQN NEKTAALEES
     GSGTNMLRQV GACRKKVMGL YRLLGNKADV IKGFAKRCNE YWEVAPKSEI GLYLGDIQDH
     ILTMTSNLTH YETLLSRAHS NYLAQINIRM NERQEQTADV LGKLTVLGTI VLPMNIICGM
     WGMNVKVPGQ DVESLNWFWS ITAGLVLFAI VCFYVAKRVY RIV
//