ID   F2S1A4_TRIT1            Unreviewed;       709 AA.
AC   F2S1A4;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=Protein SDA1 {ECO:0000256|RuleBase:RU365057};
GN   ORFNames=TESG_04764 {ECO:0000313|EMBL:EGD97353.1};
OS   Trichophyton tonsurans (strain CBS 112818) (Scalp ringworm fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=647933;
RN   [1] {ECO:0000313|EMBL:EGD97353.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 112818 {ECO:0000313|EMBL:EGD97353.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Henn M., Martinez D., Young S.K., Zeng Q., Gargeya S., Haas B.,
RA   Alvarado L., Berlin A., Chapman S., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Howarth C.,
RA   Larson L., Mehta T., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., White J., Yandava C., White T.C.,
RA   Abdel-Rahman S., Graser Y., Gurr S.J., Kohler G., Martinez-Rossi N.,
RA   Oliver B.C., Rossi A., Shelest E., Summerbell R., Lander E., Nusbaum C.,
RA   Birren B.;
RT   "Annotation of Trichophyton tonsurans strain CBS 112818.";
RL   Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for 60S pre-ribosomal subunits export to the
CC       cytoplasm. {ECO:0000256|RuleBase:RU365057}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|RuleBase:RU365057}.
CC   -!- SIMILARITY: Belongs to the SDA1 family. {ECO:0000256|ARBA:ARBA00005783,
CC       ECO:0000256|RuleBase:RU365057}.
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DR   EMBL; GG698501; EGD97353.1; -; Genomic_DNA.
DR   AlphaFoldDB; F2S1A4; -.
DR   HOGENOM; CLU_009161_2_1_1; -.
DR   OrthoDB; 5482564at2759; -.
DR   Proteomes; UP000009172; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:UniProtKB-UniRule.
DR   GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:UniProtKB-UniRule.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR027312; Sda1.
DR   InterPro; IPR007949; SDA1_MD.
DR   InterPro; IPR012977; SDA1_N.
DR   PANTHER; PTHR12730; HSDA/SDA1-RELATED; 1.
DR   PANTHER; PTHR12730:SF0; PROTEIN SDA1 HOMOLOG; 1.
DR   Pfam; PF05285; SDA1_dom; 1.
DR   Pfam; PF08158; SDA1_HEAT; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365057};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW   ECO:0000256|RuleBase:RU365057};
KW   Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW   ECO:0000256|RuleBase:RU365057};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365057}.
FT   DOMAIN          69..437
FT                   /note="SDA1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08158"
FT   DOMAIN          546..672
FT                   /note="SDA1 middle"
FT                   /evidence="ECO:0000259|Pfam:PF05285"
FT   REGION          504..527
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          557..591
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          656..709
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        561..591
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        665..709
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   709 AA;  79689 MW;  0D1C7729CC270896 CRC64;
     MGKRKLGALE KVDADLTNLQ YKIRRDPKSY VEDFRSQHLQ YENHREIFMA APSAATDTGI
     ISLIDLIDFV AHVAECYPEI TKDFPQELIE MISLHHAVLS PDLREKIVGS LVLLKRKDII
     DSSTLLQTLF PILVSTPSKT LRAFLFHKIV SDLRSANAKT TNHKLNRTIQ TVLFNLVVAD
     RSSSKALWSV KITRELWKRQ IWTESKAVEI MKEAALADNE KVIIGGVRFF LGGDKEREEL
     EDESSDDDVI DVGKVKHQAT INKGSKKRAK AIEKAKAIVK KKEKKKNAPH PLNFSALHLL
     HDPQGFAENL FQKHLQNTKA KLNIEQRLLV LQLVSRLVGL HKLTIIQLYS YFLKYLTPKQ
     PSVTSFLASL AQSCHSLVPP DTLEPLIQKI ANEFVSEGSA AEVASAGLNA IREICVRQPL
     AMNDTLLQDL VMYRKSKDKG VMMAAKGLLS LYREVGAEKL KRRDRGKDAA MGLKVGERKS
     QRYGEEEIGE IEGLELLEKW KEEERRKNRR ENGLPSDGES DEDEENENDW AAWNMEEDDS
     DDSGGWIDVQ SDVDIVFSDS DDDEPTAKKA KTDEDAIKAG DDKKTEESEA KKISRLATTR
     ILTPADLAKL AELRAAASVN ALLPENKRKR LLQQAAANRH ADDPLTAAEI EGLAALSAGK
     QTRQEKIAHV NETKTDRSEF KSKLARKKET KEKLGKSSTN KEKARKRTS
//