ID F2S8V1_TRIT1 Unreviewed; 1165 AA.
AC F2S8V1;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Transcriptional corepressor Cyc8 {ECO:0000313|EMBL:EGE00001.1};
GN ORFNames=TESG_07328 {ECO:0000313|EMBL:EGE00001.1};
OS Trichophyton tonsurans (strain CBS 112818) (Scalp ringworm fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=647933;
RN [1] {ECO:0000313|EMBL:EGE00001.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 112818 {ECO:0000313|EMBL:EGE00001.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Henn M., Martinez D., Young S.K., Zeng Q., Gargeya S., Haas B.,
RA Alvarado L., Berlin A., Chapman S., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Howarth C.,
RA Larson L., Mehta T., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., White T.C.,
RA Abdel-Rahman S., Graser Y., Gurr S.J., Kohler G., Martinez-Rossi N.,
RA Oliver B.C., Rossi A., Shelest E., Summerbell R., Lander E., Nusbaum C.,
RA Birren B.;
RT "Annotation of Trichophyton tonsurans strain CBS 112818.";
RL Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; GG698529; EGE00001.1; -; Genomic_DNA.
DR AlphaFoldDB; F2S8V1; -.
DR HOGENOM; CLU_006762_2_1_1; -.
DR OrthoDB; 20251at2759; -.
DR Proteomes; UP000009172; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR14017:SF1; LD02225P; 1.
DR PANTHER; PTHR14017; LYSINE-SPECIFIC DEMETHYLASE; 1.
DR Pfam; PF12895; ANAPC3; 1.
DR Pfam; PF14559; TPR_19; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 10.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 7.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 146..179
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 180..213
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 216..249
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 253..286
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 290..323
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 362..395
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 396..429
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 478..1165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..70
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..95
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..528
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..553
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 594..652
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 653..680
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 777..798
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 811..829
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 837..862
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 882..913
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 931..951
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 957..1061
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1063..1077
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1125..1165
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1165 AA; 129308 MW; E3A4073BE5D43ADE CRC64;
MASHPQPSPP MHPHPSHHPA LANHPQVNGH PPMAQQQAQQ QQAQAQAQQQ AAQQQAAQQQ
AQQAQQQQQP PPGPQQGPQP QLGPPGPPQQ APGQPQKGMP PTISQKIAQL NEGVWLQIGT
LSELMNDPDG AMYAFEQAIR HNQWSIPAMS AISCLLRSRE QFQKAIEYLQ AILKLDPQSG
ESWGSLGHCY LMLDNLQEAY TAYQQALYHL RDPKEPKLWY GIGILYDRYG SLDHAEEAFS
QVMRMQPDFE KANEIYFRLG IIYKQQQKFG QSLDCFRYIV NDPPRPLTEE DIWFQIGHVH
EQQKDFEAAK AAYRRVLERE PNHAKVLQQL GWLYHQQNNN YSSQEQAIEY LEKSVSADNS
DAQSWYLLGR CYMSQAKYPK AYEAYQQAVY RDGRNPTFWC SIGVLYYQIN QYRDALDAYS
RAIRLNPYIS EVWYDLGTLY ESCNNQTSDA LDAYGRAADL DPTNVQIKAR LQLLQSGQAG
GANAGNAPAP QDVHPQAYQQ NVGAPPGPQW GAPAPGPGGL PPQGPAPPAR IAEWGRPSGE
PQNASNAHGP GSQFEQRDNV RGPPPSQPRI QASPRQEQFH EPHPPYRPPH HSISSSRKGG
QSSPSPKFPL SNTHTYTGTQ VLPQLAPPQQ QQQPQQQQQP QQQPQQQHEG PNSGPAPGPP
PFPQPRQGLG PGPGHGPGGP GPNNQGPNGA GPSQYGRPFT PPAEIRPIRE ERPASANGTG
PGNGANNAGG PGPAFAPHQP YHHVPGPGGP GQQGVQQNGG IASGAPAPAS AIAAAEAAAR
ERDERPASSM KRVREWEPEP GPGAGPVKKI ANEETRSRLD GRHDARMEDQ PGPGQVPVQG
QGPPPPPPGP PPPPPQGPSR RGSPGPAGPV SGMGGLNVRL ASPRDLRRRS SSEARREDRE
HARRAHEPYH PSDAAHHPPT LPPIQHMGPK SEPQTPGQAP TGPSGGPQSL PSLSAGLPKD
ERDRDRERER DRERERERER DRDRERERER EQRERERERD RDRERDRERE REREQRDRDR
DRERERERER EQRDRERERE QRERDRDHDA RDQRDRKDHS ALPPVSVSSS VQQSQGPLEP
PARKMDVDED YDDEGDDDAG GSKKPAAMVG KGGSPGSVNG SGSVTGRDRE RERDRDGQGS
QRDRDRDRER ERERGERDGQ TKAEA
//
