ID   F2SK86_TRIRC            Unreviewed;       406 AA.
AC   F2SK86;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 2.
DT   27-MAR-2024, entry version 38.
DE   RecName: Full=Tryptophan synthase beta chain-like PALP domain-containing protein {ECO:0000259|Pfam:PF00291};
GN   ORFNames=TERG_03439 {ECO:0000313|EMBL:EGD87189.2};
OS   Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete's foot
OS   fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=559305 {ECO:0000313|EMBL:EGD87189.2, ECO:0000313|Proteomes:UP000008864};
RN   [1] {ECO:0000313|Proteomes:UP000008864}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4607 / CBS 118892 {ECO:0000313|Proteomes:UP000008864};
RX   PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA   Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA   Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA   Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA   Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA   Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT   "Comparative genome analysis of Trichophyton rubrum and related
RT   dermatophytes reveals candidate genes involved in infection.";
RL   MBio 3:E259-E259(2012).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR   EMBL; GG700650; EGD87189.2; -; Genomic_DNA.
DR   AlphaFoldDB; F2SK86; -.
DR   STRING; 559305.F2SK86; -.
DR   eggNOG; KOG1251; Eukaryota.
DR   HOGENOM; CLU_021152_4_2_1; -.
DR   InParanoid; F2SK86; -.
DR   OMA; IRHHIYQ; -.
DR   OrthoDB; 5476420at2759; -.
DR   Proteomes; UP000008864; Unassembled WGS sequence.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   InterPro; IPR000634; Ser/Thr_deHydtase_PyrdxlP-BS.
DR   InterPro; IPR001926; TrpB-like_PALP.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   PANTHER; PTHR48078:SF6; ACT DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR48078; THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED; 1.
DR   Pfam; PF00291; PALP; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR   PROSITE; PS00165; DEHYDRATASE_SER_THR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008864}.
FT   DOMAIN          58..360
FT                   /note="Tryptophan synthase beta chain-like PALP"
FT                   /evidence="ECO:0000259|Pfam:PF00291"
SQ   SEQUENCE   406 AA;  43875 MW;  4A9D9FA8097AC51F CRC64;
     MPAVETTPIT GVNYTPEEVI HAYQEIHDFV DCTPLHKVES NSALAKFLNT RISDAVPNVS
     IELYFKLENL QHTNSFKIRG LMCCLSRMSD EKLKRGIVVF STGKFQTLLV CPSDCLRISA
     RSNINIGSYG VGNHAFASGY AASLLSRMRG IQIPVHAFMP PTASKTKVYL AESQGVQVHL
     SGNSVTECMR TAEAFAESLG TSVLAPADDY DIIRGHGSVS IEIIDQMQKQ ENFGATKPDA
     ILVPTSGAAL LAGTAVYCQP HGVNVYGTEP AKGSADLLAG RKSGKRREMV DSSVNTIADG
     LRSCVAPRAW PVVSNKTYVR DVFGVNDEQI RQALKFFVAE TKTLAETSGV VPLAALLFSE
     ECKAELGRLA NNAEHGKLRL VVVVTGGNVS LEAMVEVLML DPRKNQ
//