ID   F2SRZ5_TRIRC            Unreviewed;       232 AA.
AC   F2SRZ5;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 2.
DT   27-MAR-2024, entry version 54.
DE   RecName: Full=Mitochondrial thiamine pyrophosphate carrier 1 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=TERG_05357 {ECO:0000313|EMBL:EGD89113.2};
OS   Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete's foot
OS   fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=559305 {ECO:0000313|EMBL:EGD89113.2, ECO:0000313|Proteomes:UP000008864};
RN   [1] {ECO:0000313|Proteomes:UP000008864}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4607 / CBS 118892 {ECO:0000313|Proteomes:UP000008864};
RX   PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA   Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA   Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA   Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA   Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA   Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT   "Comparative genome analysis of Trichophyton rubrum and related
RT   dermatophytes reveals candidate genes involved in infection.";
RL   MBio 3:E259-E259(2012).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC       {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR   EMBL; GG700652; EGD89113.2; -; Genomic_DNA.
DR   AlphaFoldDB; F2SRZ5; -.
DR   STRING; 559305.F2SRZ5; -.
DR   VEuPathDB; FungiDB:TERG_05357; -.
DR   eggNOG; KOG0756; Eukaryota.
DR   HOGENOM; CLU_015166_5_3_1; -.
DR   InParanoid; F2SRZ5; -.
DR   OMA; ADVWACH; -.
DR   OrthoDB; 1386779at2759; -.
DR   Proteomes; UP000008864; Unassembled WGS sequence.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR   InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR   InterPro; IPR023395; Mt_carrier_dom_sf.
DR   InterPro; IPR049563; TXTP-like.
DR   PANTHER; PTHR45788; SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED; 1.
DR   PANTHER; PTHR45788:SF2; SUCCINATE_FUMARATE MITOCHONDRIAL TRANSPORTER; 1.
DR   Pfam; PF00153; Mito_carr; 2.
DR   SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR   PROSITE; PS50920; SOLCAR; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW   ProRule:PRU00282}; Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW   Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008864};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW   ProRule:PRU00282}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|RuleBase:RU000488}.
FT   REPEAT          26..117
FT                   /note="Solcar"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT   REPEAT          128..217
FT                   /note="Solcar"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ   SEQUENCE   232 AA;  25576 MW;  5DF112A4935B6AAF CRC64;
     MAIRFTSYGY YKQYLTNPET GKLSSSANML AGLAAGVTEA VAVVTPMEVI KIRLQAQSHS
     LADPLDKPKY RSAPHALFTV IREEGVGAIY RGVSLTALRQ GTNQAANFTA YSELKKLLKD
     WQPQYTELPS YQTMCIGLIS GAMGPFSNAP IDTIKTRLQK TPGEPGQSAI SRITAISKEM
     FKQEGARAFY KGITPRVMRV APGQAVTFTV YEFLREKLEK SSWSIMGGKY EE
//