ID   F2T762_AJEDA            Unreviewed;       460 AA.
AC   F2T762;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Lysine-specific histone demethylase 1 {ECO:0000313|EMBL:EGE79075.1};
GN   ORFNames=BDDG_02013 {ECO:0000313|EMBL:EGE79075.1};
OS   Ajellomyces dermatitidis (strain ATCC 18188 / CBS 674.68) (Blastomyces
OS   dermatitidis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX   NCBI_TaxID=653446 {ECO:0000313|EMBL:EGE79075.1};
RN   [1] {ECO:0000313|EMBL:EGE79075.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 18188 {ECO:0000313|EMBL:EGE79075.1};
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Genome Sequencing Center for Infectious Disease.;
RA   Cuomo C., Klein B., Sullivan T., Heitman J., Young S., Zeng Q., Gargeya S.,
RA   Alvarado L., Berlin A.M., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA   Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA   Birren B.;
RT   "Annotation of Blastomyces dermatitidis strain ATCC 18188.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the STXBP/unc-18/SEC1 family.
CC       {ECO:0000256|ARBA:ARBA00009884}.
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DR   EMBL; GG749412; EGE79075.1; -; Genomic_DNA.
DR   AlphaFoldDB; F2T762; -.
DR   HOGENOM; CLU_016678_3_0_1; -.
DR   Proteomes; UP000007802; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 1.25.40.850; -; 1.
DR   Gene3D; 3.40.50.2060; -; 1.
DR   InterPro; IPR043154; Sec-1-like_dom1.
DR   InterPro; IPR043127; Sec-1-like_dom3a.
DR   InterPro; IPR001619; Sec1-like.
DR   InterPro; IPR036045; Sec1-like_sf.
DR   InterPro; IPR043155; VPS33_dom3b.
DR   PANTHER; PTHR11679:SF1; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33B; 1.
DR   PANTHER; PTHR11679; VESICLE PROTEIN SORTING-ASSOCIATED; 1.
DR   Pfam; PF00995; Sec1; 1.
DR   SUPFAM; SSF56815; Sec1/munc18-like (SM) proteins; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000313|EMBL:EGE79075.1};
KW   Transferase {ECO:0000313|EMBL:EGE79075.1}.
FT   REGION          275..296
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        278..296
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   460 AA;  51281 MW;  56EA64F7A576E18D CRC64;
     MAPDPGSEAE YIREKARRDL LNLLEGVRGK KNLVISKDLA GPVGLFVKFS VLQEYGVDRV
     FLLENGNVDS SQKNIVFLVH AEKPTQVQST AEQIRKLQRN GAVEHEFFIF WVPRRTLVCN
     QILEDEGIIG DVNIAEFPLY FLPLESDILS LELGNAFPDL YLHKDPGPVY LSAKALMNLQ
     LRHGFFPRIV GKGDNARKVA DQLLRMRKEL DAEETSGLNY GSSRGLMVSS TMESLIIIDR
     DVDFATPLLT QLTYEGLVDE FFEIANNQAE VDSMILGPSA PTPSSSQVTS SSTSSAAAKQ
     GLKRKIQLDS SDQLFGQLRN ANFAIVGGLL NKVARRLESD YESRHVAKSP AELREFVNKL
     PAYQAERTSL QVHANLAEDI MRQTRSDIFR KVLGVQQNVA AGSDPTYQHE IVEELIARDV
     PLNTVLRLLC LESCMTGGLR PRDLENFKNK YCKHTGTSIS
//