ID F2TCE1_AJEDA Unreviewed; 1967 AA.
AC F2TCE1;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=AMP binding domain-containing protein {ECO:0000313|EMBL:EGE80904.1};
GN ORFNames=BDDG_03845 {ECO:0000313|EMBL:EGE80904.1};
OS Ajellomyces dermatitidis (strain ATCC 18188 / CBS 674.68) (Blastomyces
OS dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=653446 {ECO:0000313|EMBL:EGE80904.1};
RN [1] {ECO:0000313|EMBL:EGE80904.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 18188 {ECO:0000313|EMBL:EGE80904.1};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Genome Sequencing Center for Infectious Disease.;
RA Cuomo C., Klein B., Sullivan T., Heitman J., Young S., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A.M., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Blastomyces dermatitidis strain ATCC 18188.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG749423; EGE80904.1; -; Genomic_DNA.
DR HOGENOM; CLU_000737_0_0_1; -.
DR Proteomes; UP000007802; Unassembled WGS sequence.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 4.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR010506; DMAP1-bd.
DR PANTHER; PTHR22754:SF32; DISCO-INTERACTING PROTEIN 2; 1.
DR PANTHER; PTHR22754; DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF06464; DMAP_binding; 1.
DR SMART; SM01137; DMAP_binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR PROSITE; PS51912; DMAP1_BIND; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 1..100
FT /note="DMAP1-binding"
FT /evidence="ECO:0000259|PROSITE:PS51912"
FT REGION 70..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 145..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 230..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 674..718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1667..1760
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1790..1967
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1..32
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 70..85
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..133
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 682..697
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 698..716
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1740..1754
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1794..1809
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1824..1838
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1846..1869
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1877..1941
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1967 AA; 218317 MW; 02ABCB41066CC4C2 CRC64;
MAEENAELQI ALRQLDQELE DGEITQKGYE KRRTLILSHY LSSNNSKRAD RGLRIGSPTV
AGHRVSQLGI YSPPSSSQGS RPASSTLSDE RRHSDSLPAN FIGREQERIA TDSMSARDSI
GSASHSMQSG NQLAQIQERE LGFSFRSERQ PSSASYDSLF LPKGPGQPGN NDSSRSGTLR
SHNYAFNPTD QPDYGDPHAS VYGPPGSSGG PTRQSTMLDS QQAFFSDFAG QQSEEHRDSY
GGGYHRYSSQ TQTEPFSPTA NMAPPFMNAV DMSHGPVVDH LLPLEPRDVT CEVHDPHNPN
VSMSQFDNLP AVVRHRARTH PKQPAYWVLD QRGKEIASIT WEKLGSRAEK VAQVIRDKSS
LYRGDRVALI YRDAEVIEFA VAILGCFIAG VVAVPINNLE DYANLNVILT STQAHLALTT
ENNLKNFQRD ITTQKLTWPR GVEWWKTNEF GSYHPKKKDD TPALVVPDLA YIEFSRAPTG
DLRGVVMSHR TIMHQMTCLS AIVASASPDG TRQAKPHGET LISYLDPRQS IGMILGVLLT
VYGGHTTVWL EARAVETPGL YASLITKYRA TLMAADYPGL KRAAYNYQQD PMATRNFKKG
TEPNFSSLKL CLIDALTVDP EFHEILADRW LRPLRNPRAR ELVAPMLCLP EHGGMVISVR
DWLGGEERMG CPLTHEMDPA GPAESNETKK EEKTETSKPG FGSSLIGGTA VPTQKESKSA
RADLDEVLLD KEALKNNEVV VLAMGEEARK QAETMPNTVR VGAFGYPLPD ATLAIVDPET
GLLCTPNIIG EIWVDSPSLS GGFWALPKHT EAIFHARPYR FQGGSPTPVV VEPEFLRTGL
LGCIIEGKIF VLGLYEDRLR QKVEWVEHGT EATEHRYFFV QHLIISIMKN VPKIHDCSAF
DVFVNDEHLP VVLLESYAAS TAPTTSGGPP RQLDIALLDS LAERCAEVLY QEHHLRVFCI
MITAPNTLPR VTKNGRQEIG NMLCRKEFDN GSLPCVHVKF GVERSVLNLP IGVDPVGGIW
SPTSSAARQG ALVMQDKQYS GVDYRDVVMD DRTSTPLNNF NSIVDLLQWR VAQQAEELSY
CSIDGRGREG KGITWKKFDT KVAGVAMYLK NKVKLKPGDH VILMYTHSEE FVYAVHACFC
LGVVALPMAP IDQNRLSEDA PAFLHLVADF HVRAILVNSD VNDLLKQKAI SQHIKQSANV
LRINLPSTYN TGRPPKQSHG CRHLGLTMKQ EWLQSGKPAM VWTYWTPDQR RMSVHIGHDT
IMGMCKVQKE TCQMTSSRPV LGSVRSTIGL GFIHTCLMGV YVGAPTYLFS PVDYATNPIS
LFLALARYKI KDTYATSQML DYAMGSMAAK GFQLHELKNL MIASDGRPRA DIYQKIRLHF
AAAGLDRTAI NTIYSHVLNP MIVSRSYMCI EPIELWLDTK YLRQGLIYPV DPDSEPNALL
VQDSGMVPVS TQIAIVNPDT SCLAHVGEYG EIWVQSEACA KSFYGTKQEF DLERFRGRVV
DGDPSAVYVR TGDLGFLHTV TRPIGPGGQP VEMQVLFILG GIGETFEING LNHFPVDIES
TIEKCHRNVV PGGSAVFQAG NLVVALIEVT RKAYLASLVP VILNAILNEH QVVADIIAFV
PRGDFPRSRL GEKQRGKILA SWVTRKMQTI AQFNIRDGEG FDSHLIDLPE RTRTAPRVPS
TAETGSRHPT PHQEPEVTAP PRQVESASAV ERPVPAEPAE SFTLPATAAS PEPRAASLRE
NDDNLNTARN SYNPLNYDFP FDDKSKDFFD DYEYDDDEPA ERPTRLAIVN PEEPDDQDNN
NNNNKYTSLP VAGPLAAGDV HYQNDNNGDD DPRTSYDHFD IDAYLSSGTP GQSAGQNHHQ
HSQQHPQGPI PSLDIIPPEN NHSNPNPHPD SRDSLPSQQA RYSYLHHQPQ MAGSTHGYDL
PQNQGHGQRQ GQNQCDTDQY RRQDYLGNDW PEEAILYQNQ SQNQERR
//
