ID   F2TRJ2_AJEDA            Unreviewed;       531 AA.
AC   F2TRJ2;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Cyclohexanone monooxygenase {ECO:0000313|EMBL:EGE85855.1};
GN   ORFNames=BDDG_08800 {ECO:0000313|EMBL:EGE85855.1};
OS   Ajellomyces dermatitidis (strain ATCC 18188 / CBS 674.68) (Blastomyces
OS   dermatitidis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX   NCBI_TaxID=653446 {ECO:0000313|EMBL:EGE85855.1};
RN   [1] {ECO:0000313|EMBL:EGE85855.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 18188 {ECO:0000313|EMBL:EGE85855.1};
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Genome Sequencing Center for Infectious Disease.;
RA   Cuomo C., Klein B., Sullivan T., Heitman J., Young S., Zeng Q., Gargeya S.,
RA   Alvarado L., Berlin A.M., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA   Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA   Birren B.;
RT   "Annotation of Blastomyces dermatitidis strain ATCC 18188.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- SIMILARITY: Belongs to the FAD-binding monooxygenase family.
CC       {ECO:0000256|ARBA:ARBA00010139}.
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DR   EMBL; GG749507; EGE85855.1; -; Genomic_DNA.
DR   AlphaFoldDB; F2TRJ2; -.
DR   HOGENOM; CLU_006937_8_0_1; -.
DR   Proteomes; UP000007802; Unassembled WGS sequence.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   PANTHER; PTHR43098; L-ORNITHINE N(5)-MONOOXYGENASE-RELATED; 1.
DR   PANTHER; PTHR43098:SF3; L-ORNITHINE N(5)-MONOOXYGENASE-RELATED; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   PRINTS; PR00411; PNDRDTASEI.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE   3: Inferred from homology;
KW   Monooxygenase {ECO:0000313|EMBL:EGE85855.1};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          5..219
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
SQ   SEQUENCE   531 AA;  60610 MW;  7E77160437C75353 CRC64;
     MTELDALIVG AGFGGVYQLW KLRNEGYQTK LVESGSDFGG VWYWNCYPGA RVDSDIPHYE
     FSMPEIWKEW TWSERFPGGP ELRKYFAHVD QKLDLRKDCL FDTTIASAIF NDNDNKWHVT
     TQGSETFKAK FLLLNTGFAS KRYTPDLKGL DTFQGQWLHS SFWPQEGLDM TGKQVIIMGT
     GSTGVQITQE AAKVAKEVTV LQRTPNLALP MAQKKYTNGE QKQPRDQYPD LFKIRPTTFG
     GFMWDFKGRN TFDDSPEKRR EFYEELWKQG DFSFWLATYQ DMLFVKESNE EAYNFWREKT
     RQRIKDPRKR DILAPMIQPH AFGCKRVSLE QDYYDVFNQD NVDVLDIKTH PLVEVTSKGI
     KTTEKEVEAD LLILATGFDS CTGGMKQIDI RGPSGISLTD KWVNGSLTYL GMSVSGFPNM
     FFTYGPQAPT ALCNGPTCAE LQGNWIADCM NYMREKNLST IDATLEAEAA WKQDVHDFAH
     ASLLPTAKSW YMGDNIPGKP RESLNYLGGV PRYMKTCRTC AEKGYEGFVL A
//