ID F2TWG4_SALR5 Unreviewed; 769 AA.
AC F2TWG4;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=CAP-Gly domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PTSG_00430 {ECO:0000313|EMBL:EGD72410.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL832955; EGD72410.1; -; Genomic_DNA.
DR RefSeq; XP_004998979.1; XM_004998922.1.
DR AlphaFoldDB; F2TWG4; -.
DR STRING; 946362.F2TWG4; -.
DR EnsemblProtists; EGD72410; EGD72410; PTSG_00430.
DR GeneID; 16067378; -.
DR KEGG; sre:PTSG_00430; -.
DR eggNOG; KOG4568; Eukaryota.
DR InParanoid; F2TWG4; -.
DR OMA; DADHIRI; -.
DR OrthoDB; 3830194at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR18916; DYNACTIN 1-RELATED MICROTUBULE-BINDING; 1.
DR PANTHER; PTHR18916:SF6; DYNACTIN SUBUNIT 1; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000007799}.
FT DOMAIN 94..136
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT DOMAIN 528..563
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 573..601
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 155..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 317..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 242..265
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 324..338
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..355
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 384..398
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 399..414
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 417..452
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 460..485
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..516
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 769 AA; 85337 MW; EA5E050DB2CE4612 CRC64;
MTRRLRSTSG SMLPPLDERQ RPSWNFSTDL HNSNGTAQSP CRCSTCRSIH RHSRRLEKKQ
RSMERLPKLP FKVGDRVLVT GDRVGLVRWV GRLDTPYINP NIHVGVHLDD PIGDTDGVLK
GKRYFSCPEQ HGVFVSKDEV ILAKGRHDLN YKMITPPDKA RPAPPLLPPV NNNATTTTTT
TTTTTNGTYA QKPATRTSSA ATRRRLHQTQ RQLAAERAGQ VAQNALKNKP WRGYIPDESD
ADAWTGSEDD ADDGGDGGDD SDSDDDVFVT GVRGPSEDER ATKELLGRVD DQHLKNVQES
VLQRARDAER LLADLELRNN RRSPAASHRQ SPSQPRSRSR SRSRSHSRVH SPHRSRNASA
RTGNGRGAER NSKAPPSPGR LSPHHHQQHQ EKQPQQKQER EASPTPSSSS RARSRSRSPR
PRNDRTTGAG RGDERGTKGA EQPKKVAAER GARAKDSANA PAKTSDDREK HDDGGHADEQ
PKAQGQDAEL RQNVQAPQQQ KQKQQASATT TAQNADGDND KGDDDMVSAD ELVRDLFAAA
DVNNNGYLNA LEFAHAAYTE TLGLALTAGQ EAQMMEAVDT TGNGRVTLDE MQPLFVNLLA
HVYGDAQGDE WQLVYSRPPY EVHFHKPSAS LDIQLPQDVD DYHRQVYAPP QNEIDLTALY
AFHAGDTTAR GSLAPDELVA VLSSPDLGLN LSQEDLDYVV AVTELEAYGE VAWPHFRLAM
RVLMAREWFE ALPPGAEWIR VDSEQFGTVF YHRETGEARY DEPEQYATY
//
