ID F2TWY3_SALR5 Unreviewed; 550 AA.
AC F2TWY3;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN ORFNames=PTSG_00602 {ECO:0000313|EMBL:EGD75892.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL832956; EGD75892.1; -; Genomic_DNA.
DR RefSeq; XP_004998068.1; XM_004998011.1.
DR AlphaFoldDB; F2TWY3; -.
DR STRING; 946362.F2TWY3; -.
DR EnsemblProtists; EGD75892; EGD75892; PTSG_00602.
DR GeneID; 16078659; -.
DR KEGG; sre:PTSG_00602; -.
DR eggNOG; ENOG502S4R6; Eukaryota.
DR InParanoid; F2TWY3; -.
DR OMA; GWNISKP; -.
DR OrthoDB; 5472182at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00051; EFh; 2.
DR Gene3D; 1.20.890.10; cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR003117; cAMP_dep_PK_reg_su_I/II_a/b.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR23064:SF81; SARCOPLASMIC CALCIUM-BINDING PROTEIN, ISOFORM C; 1.
DR PANTHER; PTHR23064; TROPONIN; 1.
DR Pfam; PF13499; EF-hand_7; 2.
DR Pfam; PF02197; RIIa; 1.
DR SMART; SM00054; EFh; 6.
DR SUPFAM; SSF47391; Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit; 1.
DR SUPFAM; SSF47473; EF-hand; 2.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 6.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000007799}.
FT DOMAIN 181..216
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 253..288
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 289..324
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 399..434
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 471..506
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 507..542
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 48..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..87
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..112
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 550 AA; 60602 MW; 797AAF56C08059D0 CRC64;
MSMSYAPHKL RPPEGLEELL WSFAKEVLRD QPKDIVKYGA QYFRAAYNER ENPSAPPPPK
PVTIVRETPT EAETTSSVQT TPAQASAPPM ETKPAQPAPE AAQLPPKPQA PPSQASAQTE
PEKPATPAQT EHEVQKPTAS VLEPESKQSK PSPPPLTFDQ QALLRKIAPN EASKEALAII
KDKDQMKSLW NQVDFNNNGI VSLAELDKLV VEKGWNISKP ALMRAYKKTT LKDGDGDAWV
EKKEFAAFMR NMFFFDRLWD VFDDIDTGDD RRIDVGEFKA GMEKLGSRLS DDEAQAEFAK
IDRNGGGQIL FKEFCHYVAG LVGAALEGDK AAFQEDTDRA AKKPGSAGAT EASKEGAAEG
SEAKPAAAPV AAKDGLNEEG LLARLGLDEA SKEALAIIKD KDQMKSLWNQ VDFNNNGIVS
LAELDKLVVE KGWNISKPAL MRAYKKTTLK DGDGDAWVEK KEFAAFMRNM FFFDRLWDVF
DDIDTGDDRR IDVGEFKAGM EKLGSRLSDD EAQAEFAKID RNGGGQILFV EFCNFIASLV
GVDLEEFTMT
//
