ID F2U4L5_SALR5 Unreviewed; 561 AA.
AC F2U4L5;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=phosphoenolpyruvate carboxykinase (ATP) {ECO:0000256|ARBA:ARBA00012363};
DE EC=4.1.1.49 {ECO:0000256|ARBA:ARBA00012363};
GN ORFNames=PTSG_03233 {ECO:0000313|EMBL:EGD82581.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate;
CC Xref=Rhea:RHEA:18617, ChEBI:CHEBI:16452, ChEBI:CHEBI:16526,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58702, ChEBI:CHEBI:456216;
CC EC=4.1.1.49; Evidence={ECO:0000256|ARBA:ARBA00001389};
CC -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC {ECO:0000256|ARBA:ARBA00004742}.
CC -!- SIMILARITY: Belongs to the phosphoenolpyruvate carboxykinase (ATP)
CC family. {ECO:0000256|ARBA:ARBA00006052}.
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DR EMBL; GL832961; EGD82581.1; -; Genomic_DNA.
DR RefSeq; XP_004995817.1; XM_004995760.1.
DR AlphaFoldDB; F2U4L5; -.
DR STRING; 946362.F2U4L5; -.
DR EnsemblProtists; EGD82581; EGD82581; PTSG_03233.
DR GeneID; 16076404; -.
DR KEGG; sre:PTSG_03233; -.
DR eggNOG; ENOG502QQI5; Eukaryota.
DR InParanoid; F2U4L5; -.
DR OMA; MRYAGEM; -.
DR OrthoDB; 3740611at2759; -.
DR UniPathway; UPA00138; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004612; F:phosphoenolpyruvate carboxykinase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00484; PEPCK_ATP; 1.
DR Gene3D; 3.90.228.20; -; 1.
DR Gene3D; 3.40.449.10; Phosphoenolpyruvate Carboxykinase, domain 1; 1.
DR Gene3D; 2.170.8.10; Phosphoenolpyruvate Carboxykinase, domain 2; 1.
DR HAMAP; MF_00453; PEPCK_ATP; 1.
DR InterPro; IPR001272; PEP_carboxykinase_ATP.
DR InterPro; IPR013035; PEP_carboxykinase_C.
DR InterPro; IPR008210; PEP_carboxykinase_N.
DR InterPro; IPR015994; PEPCK_ATP_CS.
DR NCBIfam; TIGR00224; pckA; 1.
DR PANTHER; PTHR30031:SF0; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); 1.
DR PANTHER; PTHR30031; PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP; 1.
DR Pfam; PF01293; PEPCK_ATP; 1.
DR PIRSF; PIRSF006294; PEP_crbxkin; 1.
DR SUPFAM; SSF68923; PEP carboxykinase N-terminal domain; 1.
DR SUPFAM; SSF53795; PEP carboxykinase-like; 1.
DR PROSITE; PS00532; PEPCK_ATP; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW Gluconeogenesis {ECO:0000256|ARBA:ARBA00022432};
KW Kinase {ECO:0000313|EMBL:EGD82581.1};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Pyruvate {ECO:0000313|EMBL:EGD82581.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW Transferase {ECO:0000313|EMBL:EGD82581.1}.
SQ SEQUENCE 561 AA; 61613 MW; 013EFC484660A5AC CRC64;
MPPVLEPLGP VHAAYRDTQK DAPYETSAVS DCSVNPSNHT LDNHGIGNVH QEHWNLPTAA
LYEHAVHRGE GHIVHLGPLC VRTGKHTGRA AGDKYFVREP TSEKNIAWGD VNQEMSEEAF
NWLHRKCIAY LQNRTVYVMD VLAGHDPKTQ MPVRIVTETA WHALFARTMF VRPTDEALKT
HVPKFTVIHC PGLKADPAHD GTKSSTFISL HMGKGLAVIG GTHYAGEMKK CIFTVMNYYL
PLKGIMTMHA AANVGDDDRT AIFFGLSGTG KTTLSADESR KLIGDDEHIW SDEGVANIEG
GCYAKVIRLS AQAEPTIWHT TRQFGTVLEN VIMHPVTRTL DLSDNSITEN TRAAYPLQFV
PNRQASGCGG HPANVIMLTC DAFGVLPPIS RLTPAQAEYW FLLGYTAKVA GTELGVTKPT
ATFSACFGLP FMPLHPTVYA KLLREKMEKH NVSVWLLNTG WSGGPYGVGE RFSIKHTRSM
LAAALDDKLQ DVPLKKHETF NLNMPTSCPG VPEDVLDPRN TWSDAAAYEK QANELAALCV
EGFKPFVDAV TPDVLETAPR A
//
