ID F2U893_SALR5 Unreviewed; 407 AA.
AC F2U893;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=GPN-loop GTPase 3 {ECO:0000256|ARBA:ARBA00014587, ECO:0000256|RuleBase:RU365059};
GN ORFNames=PTSG_04337 {ECO:0000313|EMBL:EGD72601.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Small GTPase required for proper nuclear import of RNA
CC polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly
CC step prior to nuclear import. {ECO:0000256|RuleBase:RU365059}.
CC -!- SUBUNIT: Binds to RNA polymerase II (RNAPII).
CC {ECO:0000256|RuleBase:RU365059}.
CC -!- SIMILARITY: Belongs to the GPN-loop GTPase family.
CC {ECO:0000256|ARBA:ARBA00005290, ECO:0000256|RuleBase:RU365059}.
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DR EMBL; GL832964; EGD72601.1; -; Genomic_DNA.
DR RefSeq; XP_004994424.1; XM_004994367.1.
DR AlphaFoldDB; F2U893; -.
DR STRING; 946362.F2U893; -.
DR EnsemblProtists; EGD72601; EGD72601; PTSG_04337.
DR GeneID; 16075008; -.
DR KEGG; sre:PTSG_04337; -.
DR eggNOG; KOG1534; Eukaryota.
DR InParanoid; F2U893; -.
DR OMA; HTEDDYI; -.
DR OrthoDB; 168004at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd17872; GPN3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004130; Gpn.
DR InterPro; IPR030228; Gpn3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR21231:SF7; GPN-LOOP GTPASE 3; 1.
DR PANTHER; PTHR21231; XPA-BINDING PROTEIN 1-RELATED; 1.
DR Pfam; PF03029; ATP_bind_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|RuleBase:RU365059};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU365059};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU365059};
KW Reference proteome {ECO:0000313|Proteomes:UP000007799}.
SQ SEQUENCE 407 AA; 46972 MW; B2F3D16B0BBF7704 CRC64;
MRYAQLVVGP AGSGKSTYCS TIYSHCQNIK RPCHVVNLDP AAEHFDYDVA VDVRELISVD
DAAEYMNLGP NGALIFCMEY ILKNLEDFGE KLGDFEDDYL LIDCPGQIEL YTHMPLMTRL
TNHLQTLGFR LVVVYLLDSQ FMCDPAKFFS GAIAALSAML QLELPHVNVM SKMDLVPKEV
RPLIESYMNA DTHVLLDELN RTADDKRRRL NLRLAELIEE FGLLQFYPLD KDDEEMITDL
VLHVDMCLQY GEHEEPRDVD RMDMADMHWW RERGVSDEDE DVELLSAARV LTQRRTWFGF
GQTQEYDTSP PKPWYQRHAR DDTDEFDRFS TEERKERIAL RREMMDLQED GADSTNLEAY
AAKVADLCIK YNDRLGAAAL VDNSDFVQLP EVNKAALEEF LEKTKFD
//
