ID F2U8E8_SALR5 Unreviewed; 1838 AA.
AC F2U8E8;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGD72656.1};
GN ORFNames=PTSG_04390 {ECO:0000313|EMBL:EGD72656.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL832964; EGD72656.1; -; Genomic_DNA.
DR RefSeq; XP_004994479.1; XM_004994422.1.
DR STRING; 946362.F2U8E8; -.
DR EnsemblProtists; EGD72656; EGD72656; PTSG_04390.
DR GeneID; 16075062; -.
DR KEGG; sre:PTSG_04390; -.
DR eggNOG; KOG1217; Eukaryota.
DR eggNOG; KOG1219; Eukaryota.
DR InParanoid; F2U8E8; -.
DR OrthoDB; 2949885at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 4.
DR CDD; cd00173; SH2; 1.
DR Gene3D; 2.60.40.60; Cadherins; 7.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR039808; Cadherin.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR013111; EGF_extracell.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR001846; VWF_type-D.
DR PANTHER; PTHR24027; CADHERIN-23; 1.
DR PANTHER; PTHR24027:SF445; CADHERIN-87A; 1.
DR Pfam; PF00028; Cadherin; 2.
DR Pfam; PF07974; EGF_2; 1.
DR Pfam; PF00017; SH2; 1.
DR Pfam; PF01833; TIG; 1.
DR Pfam; PF00094; VWD; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 4.
DR SMART; SM00252; SH2; 1.
DR SMART; SM00216; VWD; 1.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50268; CADHERIN_2; 7.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50001; SH2; 1.
DR PROSITE; PS51233; VWFD; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..1838
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003290404"
FT TRANSMEM 1592..1617
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 139..329
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 664..767
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 767..868
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 875..967
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 982..1074
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1075..1182
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1192..1313
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1308..1405
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1673..1773
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 1549..1583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1838 AA; 198575 MW; 8AD5A5E31B031390 CRC64;
MAALRMLGLC VMLLVASAAA QRIHVDKTSL TVSEGFYEVI TFTLDEPIIC TTQDGECAVV
IEVQNPHPNQ VAIDNCIIKW DWQDWHQPRT LVIRAVEDFV DDGTFEGMIV TDPAISRSEY
YKNYNAADIV IKTRPRRSAQ CSGTGDPHYH TFDRKYWHIV DAGRYVLYKT RSRTFEVQVQ
TRAYPARHCA FAAREDNDVV VVWACNGNPV VRRSCGSDEC RRGGFPKLSI RGSSRRANYY
VEFKSGAMVR ADTQPYYMSM YLTAPGRDFN DVEGVCGNFD GNPNNDAPVY YARSVNQLWS
SQRPSYDLFA WYPSPSPPSP PPRSYEECTY EEPPFVRPIL NRPDAEDITS FIKDLNLNDV
IDNEDVVIGG SSVDESLNAM DRNLAVAQCD DVISNSHVVA VCQNNLPGFD FTAYIEDCAD
DLAETSNVDF IEDALEALER DCAERASRDL NTWETDENEN PVEPNKEIQT NICPSQCNNR
GTCDEGICTC DEGFLGFDCS IDTNARPVIT SLVKPFCDTK GINECTGRLS VIGEGFWNSD
KLRCRFGDME TDAFFLGSME VACAVPNKVH SGSDEETAVV QVTVDGDNWS ESQEFVFTWY
DGVCQVCNAH GCGPNPESCT IDGTCYHNTA PNSDNICQQC DPSTSVTEWT WTYQNHEECG
PSFPKGTPTV TVVGGAEAGD VIYTVDASNS KVAADTSNVI TYSLTGGDGL FAISNDGVIT
AAQAFNVLDL DVTFNNFLSI VATDSAGNEA TTGIVIDAVA ENVDPYFSDS YSVEVPEDVQ
VGSVIISVQA QDRNEDDSLT YSWFSTEEGY GDYFLIDETT GDVTVNRELD FEDRDLFTLV
VRARDNGGQT HVTTLEVTVT DVAEAPNGVA IDSDSLEENS APGTVVGTLS TQDPDDVDGT
QSFTYSTSSS VFAIDGDKLV TAPGSSFDFE AGPTEYEVEV TTTDQDGLTF TDTLTVSIVD
VNEKPYNVRL NIPGSEQGNF MIEESAPLDS IVGTIEKQDD DADQTVLCSL ASTDNGHFEI
SGNNLVLIDQ LDYEEDNEHM ITVVCVDDGT PTLASDPVTF VIHVTNVDDG PSDFAFEGTD
VSVPEDAQVG DVVARVVAVD VDGGDSAFDF SIVRGKFAVP NAPDCEAQQD GSVRCVVDLV
LAEALDFETA EEETFTIEAD SNGRVGSARL TIPVANVNEP VSAIQWADGV NTIPEDVDAG
VLVGTLLPVD PDTTTMGVAY NFELLTNTDV FELVPLMASA GSSRRRRAND ADAYGAEVRV
KDPSALDYED ESKRSFTLSL RVTDNADTPV SSVVEATVEV TDAPLRLVTA PDFITVSENA
SVNTQVATVS LEGNDHAGVP YTITLVDDAN GAFRLDGDKI VVNGALNFEV AQAHELTFEV
DTQETPLPTF AVVVGVRNVD DAPVISIDSV MQEVNSDIRV GQTVFSVDAT DEDGTGVDVQ
LEVSAGSLTR ESLLLQVFGY RASTQSVFVR QTPSTAGLPL GTYHMRLVGT SGIGSTSVEF
TITVFDDCRS NQCAATETCV DRFGSYDCCE GATCVNSADA GFDTRFDTTT TTTQAPSTSN
SADTTTDENG NGPNGGNVDL SRTDASNSGA SVGLIVGVVV GAICLIALVA VVVILAMRRR
NDPGRLFLAA EEGSKTYMSN PTYRSPQEPV YAQADGRQTV AFVPGASNPL YEWYQPDMTR
QECTDSLTDA PAGSFIVRDS KATPGWHMIG VRTESAVVHE KIKRGDDGMY ELLPASNAPQ
PAFQDIPSLV YHYSEPRADV PFVLSASSLS NPMYAMSQNA STGQYAYAPG SAIPHDAAAP
AVPIKEKERA AVEQVAAMDD GELYTNTTDA QAALHSSA
//
