ID F2UCX1_SALR5 Unreviewed; 787 AA.
AC F2UCX1;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=LIM zinc-binding domain-containing protein {ECO:0000259|PROSITE:PS50023};
GN ORFNames=PTSG_05830 {ECO:0000313|EMBL:EGD74466.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the costars family.
CC {ECO:0000256|ARBA:ARBA00006126}.
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DR EMBL; GL832969; EGD74466.1; -; Genomic_DNA.
DR RefSeq; XP_004992723.1; XM_004992666.1.
DR AlphaFoldDB; F2UCX1; -.
DR STRING; 946362.F2UCX1; -.
DR EnsemblProtists; EGD74466; EGD74466; PTSG_05830.
DR GeneID; 16073294; -.
DR KEGG; sre:PTSG_05830; -.
DR eggNOG; KOG1700; Eukaryota.
DR eggNOG; KOG3376; Eukaryota.
DR InParanoid; F2UCX1; -.
DR OMA; WCTHTHT; -.
DR OrthoDB; 6059at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd09358; LIM_Mical_like; 1.
DR Gene3D; 1.10.10.1540; Costar domain; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 1.
DR InterPro; IPR044302; Costars.
DR InterPro; IPR027817; Costars_dom.
DR InterPro; IPR038095; Costars_sf.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR46334; COSTARS FAMILY PROTEIN ABRACL; 1.
DR PANTHER; PTHR46334:SF1; COSTARS FAMILY PROTEIN ABRACL; 1.
DR Pfam; PF14705; Costars; 1.
DR Pfam; PF00412; LIM; 1.
DR SMART; SM01283; Costars; 1.
DR SMART; SM00132; LIM; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
PE 3: Inferred from homology;
KW LIM domain {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 715..775
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 82..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..137
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..411
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..443
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..506
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 520..553
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..591
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 787 AA; 89655 MW; 2CB7A407081ED457 CRC64;
MLLKANLQVA LLFVDTPPPP TLHTTSSTSR SLASVRHRAA RVRTHIELHP SPCGEHTKWC
THTHTHLRLT TPRLGAKQAV MGNSKSKGAT SAAMPADAAA NGHAIQGQRR MSRAEKKALK
QSKKQALAEE KQRKKEAKKE ARKSRKNGGA KNKDNNQPQH DAAAAAHASK RNNAGADDAR
EEMERIKDEE VRQQQAEEAR RRDNDRVEAQ EELQHLKRME AKRTEEERAA KAKAAAAAKE
DDRQQEEAQQ RHREEEERRK QREREQAEAA RQKEEEKRRK EEEKEQRKQQ EAAEELQRMK
REQEEAEARR RKKEAEEEEE RKRKQQQQEE EERKRREAEE AERKRKEQEE AERKRKEQEE
EKERQRKEQE EKERQRKEQE EAEARRKQEE LERQAKEAEE KRRKEAEALA AADAKQKAFA
AARQREEQEK KKREEEAKEQ AKQQAAADES VSHVSPFGAR LRKVSKDNVN TDASAQQQQQ
QQQQQQQQQQ QQGGGATDTA ATPAASVSSP FGAKLKPLSS SALVTPTGTP KATSTANTPQ
QAATTSNSST PAGGLRPMKL RNEFPGLKKQ DDSTSSSSKK PAGDDDEYEE LDPRAIEAAK
WVDKEIRKLI GEIQRLGSPN GDGKYTVKFG HLFVETANIF EALTGTLKTA KKYKVVTYEG
EVLYQGSSDH VTVTLLKDTH DGVEIKRRKK RDLKAPGLKA KSKGFSTSSL QHAQQKCYIC
KKTVYPMEFV GAADKAFHKN CFRCKECKTV LKPTEYCTVD DQFYCRTHYT QLFMSGGYTH
AQRGTDE
//
