ID F2UD48_SALR5 Unreviewed; 746 AA.
AC F2UD48;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE RecName: Full=N-acetyltransferase domain-containing protein {ECO:0000259|PROSITE:PS51186};
GN ORFNames=PTSG_05907 {ECO:0000313|EMBL:EGD74543.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
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DR EMBL; GL832969; EGD74543.1; -; Genomic_DNA.
DR RefSeq; XP_004992800.1; XM_004992743.1.
DR AlphaFoldDB; F2UD48; -.
DR STRING; 946362.F2UD48; -.
DR EnsemblProtists; EGD74543; EGD74543; PTSG_05907.
DR GeneID; 16073371; -.
DR KEGG; sre:PTSG_05907; -.
DR eggNOG; KOG2036; Eukaryota.
DR InParanoid; F2UD48; -.
DR OMA; HTCIMLN; -.
DR OrthoDB; 1119820at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR CDD; cd04301; NAT_SF; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR000182; GNAT_dom.
DR InterPro; IPR007807; Helicase_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032672; TmcA/NAT10/Kre33.
DR InterPro; IPR013562; TmcA_N.
DR InterPro; IPR027992; tRNA_bind_dom.
DR PANTHER; PTHR10925; N-ACETYLTRANSFERASE 10; 1.
DR PANTHER; PTHR10925:SF5; RNA CYTIDINE ACETYLTRANSFERASE; 1.
DR Pfam; PF13718; GNAT_acetyltr_2; 1.
DR Pfam; PF05127; Helicase_RecD; 1.
DR Pfam; PF08351; TmcA_N; 1.
DR Pfam; PF13725; tRNA_bind_2; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR PROSITE; PS51186; GNAT; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 232..409
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
FT REGION 616..635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 660..746
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 670..704
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 705..746
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 746 AA; 84055 MW; 33ECE23D9D28A099 CRC64;
MKKRIDRRVR TLIENGVHTR QRTCMVLVGS NAKDQVVNLH FMLEKASLRA KPSVLWCYKK
DLGFTSYVYS FVIDEAAAIP LPLVKDLMGP YIVFMASTIN GYEGTGRSLS LKLIQQLRKQ
AGVAASKGAT HSKLRELTLD IPIRYAANDP VEAWLNGLLC LDSTIAPPSA GACPHPSACD
LYSIDRDTLF SYNKVSEVFL QRMVALYVAS HYRNTPNDLQ LLSDAPAHRV FCLLAPITNP
QELPEILCVI QVALEGEISA KTVRATLKQG IKQAGDLIPW TICQQYQDDD FGQLSGARIV
RIATHPDYQG MGYGKRAIEQ LKAFYDGKLL DLSESGTREK IEAHSLELHE EDHESLTPRK
NLPPLIRKLD ELEPDTLDYL GVSYGATPSL YKFWKKCGFA PFYMRQTAND LTGEHTCIML
NPLETARLNG KWLRSYWLDF QQRYMVLLGS AFRHFPPALG LGVLEPVPCV SLEDDEEEEQ
KHLLTVDELM THFTPHDLKR LQAYVNQMAD FHIILDLVPR AARLFFTQKL PVRISPAQQA
ILLGLGLQHK TIEDLEKGMG LGSAQLLGLF RRAVEQINKA FRRLREKHIE AQLPKTRLEF
AGEAVEENLE EQLEEAGREE MKKLEEEEHT EQVDQERREL LLQTFSKYSI DVDDETFEKA
VSGKTEVSRV SIPRKQELKP AGEDDGAKRR ADDDADEFDM KGKKAKKGKK SNKSTPSKKG
KKGTPSKKDK GTPGKKKKGG KKGGRQ
//
