ID F2ULE9_SALR5 Unreviewed; 885 AA.
AC F2ULE9;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
GN ORFNames=PTSG_09581 {ECO:0000313|EMBL:EGD77948.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL832980; EGD77948.1; -; Genomic_DNA.
DR RefSeq; XP_004990011.1; XM_004989954.1.
DR AlphaFoldDB; F2ULE9; -.
DR STRING; 946362.F2ULE9; -.
DR EnsemblProtists; EGD77948; EGD77948; PTSG_09581.
DR GeneID; 16070563; -.
DR KEGG; sre:PTSG_09581; -.
DR eggNOG; KOG2710; Eukaryota.
DR InParanoid; F2ULE9; -.
DR OrthoDB; 25176at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR15228; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR PANTHER; PTHR15228:SF25; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007799}.
FT DOMAIN 75..275
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 340..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 442..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 500..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 569..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 694..871
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..369
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..413
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..463
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..521
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 716..740
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 741..761
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 841..871
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 885 AA; 97136 MW; F7A42BB5FE5B24A3 CRC64;
MSSNDNADRR MEAAALQMLQ TARVGIVFTI HKDKKRKDDL VQGRYFSWLA SQPPSFHMSR
PLADIMADKE LTVQVDLEGV KLTIPRLVYE ICTYLRRSRQ LGTEGLLRKS GNASRVRMLQ
QHLDAYGKLP IKELKENKYT CHDLIQVLKT FLRHLPGGII HSLYKSFVIA QRVKHEEDHV
TRRSDEEIAQ FGLKMTLCLC YLLPTPNQHL LQYLMHFFVD QFGPAQQERQ SQNTMTLDNI
ARILGPTLLP TGGTTSKPGS EDEAEFVIDA VRDMMHGYKR GQLYTSYLKE VCDRAALISP
QEAQRLYKSG FADKYAKPKR RSRASGLGDA LRSAGEEMMK TLQRRGSSRS NIADKSTTAS
RSASTQGTPK MRRKGRRSLG DPETLAAMAK QPELNTTNGG MSTTSSFPST SSSSSATIAT
ATAAATSSSS GVRVAAVTRS RSLKRTSDAA HPELADDNAR QKFKFGDQPP AKAPATKRPG
RIISAAEAKR KAFDIAPVHD PRQQAKVAPK RTSSEPTGLH TTAATTTRTT PITTGSAVAA
FNTTSGTLTA TNSTDSDEPM KPSAVTVSRV STTDISHEQS AVVRRHTKTQ TPRSRRRSFE
GMRRLGDGLT GSAKKVRNFM QRRRSSRAGS MKKKSSSTSS IADTNKENDD DNEGSRDLFL
NLLPQTSQND SDVITLEELN RFSQMCYEAQ EKLDSSKAAS GQTPARLRDA HAVTRAKHAS
SSSSSSSTIA TSGVSMNSDS TRDATKHRVV DAKELQRPPR KTRVGKPLVI RHPAASRFGV
GRLSAGDDTP SRGLLDTPSS TYVRKTRRTP IGRASPPPTL SISPARATDT SDANACKRGK
RTPARSNNSS TKSQRTALGD INNKSPKVSN HRTPLLQQED RFTFV
//
