ID   F2UNQ1_SALR5            Unreviewed;       553 AA.
AC   F2UNQ1;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=Pre-mRNA-splicing factor 38 {ECO:0000256|RuleBase:RU367025};
GN   ORFNames=PTSG_09980 {ECO:0000313|EMBL:EGD79256.1};
OS   Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC   Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX   NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN   [1] {ECO:0000313|Proteomes:UP000007799}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA   Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA   Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA   Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA   Birren B.;
RT   "Annotation of Salpingoeca rosetta.";
RL   Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for pre-mRNA splicing.
CC       {ECO:0000256|RuleBase:RU367025}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU367025}.
CC   -!- SIMILARITY: Belongs to the PRP38 family.
CC       {ECO:0000256|ARBA:ARBA00006164, ECO:0000256|RuleBase:RU367025}.
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DR   EMBL; GL832984; EGD79256.1; -; Genomic_DNA.
DR   RefSeq; XP_004989341.1; XM_004989284.1.
DR   AlphaFoldDB; F2UNQ1; -.
DR   STRING; 946362.F2UNQ1; -.
DR   EnsemblProtists; EGD79256; EGD79256; PTSG_09980.
DR   GeneID; 16069885; -.
DR   KEGG; sre:PTSG_09980; -.
DR   eggNOG; KOG2889; Eukaryota.
DR   InParanoid; F2UNQ1; -.
DR   OMA; QNRMGAY; -.
DR   OrthoDB; 5485563at2759; -.
DR   Proteomes; UP000007799; Unassembled WGS sequence.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:UniProtKB-UniRule.
DR   InterPro; IPR005037; PRP38.
DR   PANTHER; PTHR23142:SF1; PRE-MRNA-SPLICING FACTOR 38A; 1.
DR   PANTHER; PTHR23142; UNCHARACTERIZED; 1.
DR   Pfam; PF03371; PRP38; 1.
PE   3: Inferred from homology;
KW   mRNA processing {ECO:0000256|ARBA:ARBA00022664,
KW   ECO:0000256|RuleBase:RU367025};
KW   mRNA splicing {ECO:0000256|ARBA:ARBA00023187,
KW   ECO:0000256|RuleBase:RU367025};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367025};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW   Spliceosome {ECO:0000256|ARBA:ARBA00022728, ECO:0000256|RuleBase:RU367025}.
FT   REGION          199..553
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        230..244
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        258..288
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        289..331
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        344..403
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        417..475
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        476..499
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        515..541
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   553 AA;  64982 MW;  07A652A170978E7C CRC64;
     MANRTVKDAR SVHGTNPQFI VDKIIRSRIY ETLYWKEQCF ALTAETVIEK AVELTYVGGV
     YGGNIRPTPF LCLTLKLLQL QPDKDIIIEY IKNEDFKYLR ALGAFYLRLV GTSMDCYRYI
     EPLLNDYRKL KRMSRNGVME LTHMDEFVDE LLREDRVCDI GLPRIQKRYA LEVNDELEPR
     RSLLEDELDD FEGELQAAAA AGTGGGGEED TTGSGGGDGG DAQKRKAEED EEEGEEDEEE
     GRTGGDGSGD ESDRHHHRRR SPSRSPRRSR SRSHSRSRER GGRHRSRSSS RGRDRDRDRD
     RDRDRDRDRD RDRDRDRDRD RDRDRDRSGR SDSRTRRRHR SRSRSHDHDD YDDRDRYSRR
     YHRDRDRDRR SRRHDDDDYD DRRRHRRHRD SRDRSISPSD RTRTRRRSRS RSRSRDRGRR
     YGRERYSRGE RDGSRERESE RRRSRSPSPS RRDGGDDERE RRVVESERRT RDEETAPSSS
     SSARKPAESS ASSGGSGSHR LRFKGQKDSK KKKKKKRDKD SEAEGSKDTA KTPEDEIAEM
     NALRAKLGMA PLK
//