ID F2UQB4_SALR5 Unreviewed; 1092 AA.
AC F2UQB4;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=WD-repeat protein {ECO:0000313|EMBL:EGD79782.1};
GN ORFNames=PTSG_10767 {ECO:0000313|EMBL:EGD79782.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL832988; EGD79782.1; -; Genomic_DNA.
DR RefSeq; XP_004988731.1; XM_004988674.1.
DR AlphaFoldDB; F2UQB4; -.
DR STRING; 946362.F2UQB4; -.
DR EnsemblProtists; EGD79782; EGD79782; PTSG_10767.
DR GeneID; 16069266; -.
DR KEGG; sre:PTSG_10767; -.
DR eggNOG; KOG0266; Eukaryota.
DR InParanoid; F2UQB4; -.
DR OrthoDB; 3385905at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22847:SF637; WD REPEAT DOMAIN 5; 1.
DR PANTHER; PTHR22847; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF00400; WD40; 3.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT TRANSMEM 330..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 713..737
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 774..794
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 806..832
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 844..863
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 946..971
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 172..214
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 215..256
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 257..298
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 773..975
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 1..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 535..569
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..96
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 538..569
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1092 AA; 117782 MW; FDDB06E0708D88D1 CRC64;
MDDDDMPLFK GNAEVKEEES GADALFPTGA ASDHDQQQTT NTVTASANSF HHQQHQQQQQ
QQQSSTDAYA EQARSEAPPN QVPSVTQQQP WQQRHASSGP APKVEDLSPL VISSRTLGLS
GFQTGPANGE YAEPPSSATA VCLVSQTLVA TGHDNGLVSL WNRNSLQLVC TLSGHTGRVT
SLATTDNNGA WLVSGSQDNT LRVWDVNTFR CYTMLQGHTA AITSLTAIPN TNMVASGSED
ATVCIWDIEH RMCVTTLQGH TDTVADVAAM PSGSQVVSLG TRGQCRVWDT PTGEHITLTK
NNTHIHAIAT SVHHPDTIIA LQRTRQTDSA WTVVLASSLI ACVIGIVLMA TDTSFHSAGY
AGAAVCGVGA IGLCLCFILR HFGFGFASGP CTAVHAYSTH APKRQVLVSG KYSQCALTAK
YVVLAGEDGM ALVDAKSLTL RAQFVLPHAH THDHTCSVAV DKGEGELCIL EDGSHLTLFD
LTTAWAGAHN PLILLQLALS GKIPPEYVHK DHTRRAIALL EADRSEAVFE TARDALRSKQ
QHQQGGDQPQ TQAQGDGVHQ PPPEQQQQQQ QVQALPSAQD SLQDSDHLNL LMWHAVVNTD
HAAALDLMKE LLELPPLDVG EWRSPLLAGI RPGDFVVLDE DMLHGDDADL KKELHSKSEP
GVVKVTTQAL RLDTEWFAEL LISLIRTGDP RFFTILPVRA AVKAMWHSQL DLFLVRCLFQ
MGATAMLVYC ALSGSLLGPE RTWQKFTVLV LGIGELWQAG SIVRDYRVSL TSFWYWNSFA
RTISLVCLGL IAVIEQPSLQ GVPTTLALSL LFHWVGLLEF TFAFDGLARA VIAITHVIRR
CASFLLVLAV AAMAAASCMF VLFGDTTSAS SAATGVTIPT TTTPYNPYNR NRYPFTTPSS
ASKSGSSSAL KITGLTLFDT AIHLMFGQLS ASVLDNAGDV PSATRAILLA IITLALIVLL
SMLIAVVFTA YERIQDGVEP HLARTRAIIA SQRHTGPLQL LVWYILQLAR GGNSGGESGG
DGRWRNGVVF IPADTPQQQE PRGSGWRGGV KQRVDALQDT VNVDMAKLHE TIAAFRAEMQ
AMSMMAANES TA
//
