ID F2USF0_SALR5 Unreviewed; 560 AA.
AC F2USF0;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
GN ORFNames=PTSG_11002 {ECO:0000313|EMBL:EGD81059.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL832994; EGD81059.1; -; Genomic_DNA.
DR RefSeq; XP_004987928.1; XM_004987871.1.
DR AlphaFoldDB; F2USF0; -.
DR STRING; 946362.F2USF0; -.
DR EnsemblProtists; EGD81059; EGD81059; PTSG_11002.
DR GeneID; 16068455; -.
DR KEGG; sre:PTSG_11002; -.
DR eggNOG; KOG4269; Eukaryota.
DR InParanoid; F2USF0; -.
DR OMA; CACKDES; -.
DR OrthoDB; 1333388at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23176:SF129; RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007799}.
FT DOMAIN 128..327
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 335..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..359
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 560 AA; 61410 MW; 7B2DB3FB3F65F8B0 CRC64;
MAEGGSVQLR LLHLKGLRLA LRSSDVAVTC KTDTSFGPHR ARAVITKRTS YEQQPSLTVG
IEGAKFLKVI VADLLTFGRE SVVGTATIDL QQLAIAVGST RTLSLPLSPQ GEVKVWIRFL
GSRPMFGVDL QAITQREGTT VPRIVTRCIR AVEEAGLGVE GIYRVPGSQP AIDALKASFQ
ETQGQFEFKK EHLVSINNVA SLLKQFLNAL PRSLLHSQAA TMLAIFSKGA PSTMNRALFE
SFMAVDEPSR ATALALLTHM RKIAKHSDKN QMTFSNLATC FGPNLISHPS TPTHAPTTAE
EMHRIASQSR ECNAFVSYLL GQDDLLCACA CKDESKLESD GPPSPVSASS SSSSTLSTSS
ASAHRRPLDV FQQHQPVDFT AFRLVCHELG WYVARDEEHV FAEAADGAST ISWRQFKRWW
EESDRSKLSS QKLYALKRAA RFFMLFAIHD AADPVQRSVT ADECAVVQSA VRCSDGCGAH
VRVGVSLENS CSRAHLLVLF VLLHCLVLLC PHLFPVSTPP LSSIHTHTHA HTKVHAHSLL
SSVYVNFPLR LHYRQQPETL
//
