ID F2USL1_SALR5 Unreviewed; 701 AA.
AC F2USL1;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=protein-serine/threonine phosphatase {ECO:0000256|ARBA:ARBA00013081};
DE EC=3.1.3.16 {ECO:0000256|ARBA:ARBA00013081};
GN ORFNames=PTSG_11157 {ECO:0000313|EMBL:EGD81120.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL832995; EGD81120.1; -; Genomic_DNA.
DR RefSeq; XP_004987805.1; XM_004987748.1.
DR AlphaFoldDB; F2USL1; -.
DR STRING; 946362.F2USL1; -.
DR EnsemblProtists; EGD81120; EGD81120; PTSG_11157.
DR GeneID; 16068327; -.
DR KEGG; sre:PTSG_11157; -.
DR eggNOG; KOG0930; Eukaryota.
DR eggNOG; KOG2283; Eukaryota.
DR InParanoid; F2USL1; -.
DR OrthoDB; 5477362at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR Gene3D; 2.60.450.20; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR047002; Tcp10_C_sf.
DR InterPro; IPR029023; Tensin_phosphatase.
DR PANTHER; PTHR12305; PHOSPHATASE WITH HOMOLOGY TO TENSIN; 1.
DR PANTHER; PTHR12305:SF81; PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS51181; PPASE_TENSIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007799}.
FT DOMAIN 268..374
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 419..601
FT /note="Phosphatase tensin-type"
FT /evidence="ECO:0000259|PROSITE:PS51181"
FT REGION 126..201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 535..701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..185
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 535..582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 654..695
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 701 AA; 75770 MW; 7733EDA4799DA443 CRC64;
MSAPKETTTS SLPVDESREA VEAAIQCADS TRQVAEDEDV TVNRSVNGIL MQYANNTKIE
VLSNEATRVK LSDGTVIEKF PNGAQTISLP NGVVVETKPD GTKMIRSASS DKIVKEFPDG
RKVVLSADSA SEDDRAATTI SQPPPDDLDE DTTSDEEEED ALVEALQSLA EQDDEDDDDA
DDGDDGDRIS ATAASGADGS VAAARTGSVS KHAAAAAATG GVRSVVDGDV VGTGHGDGAA
MAQGHMGERA GSVSRTASKD VDVPIHNSII VCGWLWKEGG QIKSWKKRYF QLTEFNMLEY
YDREPHRGGR FINVIDVFGG QVTPADDARR PHSFHLYVSC EPGTVSNKRS KYKLAALSGA
DREAWMEKLR VSAASKERNL TSVEQRPVVT RKFASRVVSL AKGPSLTNTV RKLVSKKKVR
YQRDGFDLDL TYITPRIIAM GYPAEGTEAV YRNSYEDVYR MLQENHASHY KVYNLCSERA
YPASRFHNRV ADNKLRLTRQ EIDGAHKRKH LKIFNPSFAV TLYFDDVEWA SKDTATTTTQ
DGNDDNDNIN DDATPTTTTA ATNEDDDDAN TTTTTTTAAA TATLKPVHPA SMRVKSGISR
TSRPGSLVPR RGAPHVSPPH AQDTRAAEAD AGEAETEGGA EGIAEGGDDD GAVEEQATAD
KGMVKGEEAE QPQQQEEEME GKEGMQEKEG PAQESSPTDD Q
//
